scholarly journals Application of a mobile laboratory using a selected-ion flow-tube mass spectrometer (SIFT-MS) for characterisation of volatile organic compounds and atmospheric trace gases

2021 ◽  
Vol 14 (9) ◽  
pp. 6083-6100
Author(s):  
Rebecca L. Wagner ◽  
Naomi J. Farren ◽  
Jack Davison ◽  
Stuart Young ◽  
James R. Hopkins ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Mass Spectrometer ◽  
Temporal Resolution ◽  
Trace Gases ◽  
Mobile Laboratory ◽  
Flow Tube ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube

Abstract. Over the last 2 decades, the importance of emissions source types of atmospheric pollutants in urban areas has undergone significant change. In particular, there has been a considerable reduction in emissions associated with road vehicles. Understanding the role played by different source sectors is important if effective air pollution control is to be achieved. Current atmospheric measurements are made at fixed monitoring sites, most of which do not include the measurement of volatile organic compounds (VOCs), so our understanding of the temporal and spatial variation of pollutants is limited. Here we describe the application of a mobile laboratory using a selected-ion flow-tube mass spectrometer (SIFT-MS) and other trace gas instrumentation to provide on-road, high-spatial- and temporal-resolution measurements of CO2, CH4, VOCs and other trace gases. We then illustrate the potential of this platform for developing source characterisation methods that account for the similarity in correlation between species. Finally, we consider the benefits of high-spatial- and temporal-resolution measurements in characterising different types of sources, which would be difficult or impossible for single-species studies.

scholarly journals Application of a mobile laboratory using a Selected-Ion Flow-Tube Mass Spectrometer (SIFT-MS) for characterisation of volatile organic compounds and atmospheric trace gases

2021 ◽  
Author(s):  
Rebecca L. Wagner ◽  
Naomi J. Farren ◽  
Jack Davison ◽  
Stuart Young ◽  
James R. Hopkins ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Mass Spectrometer ◽  
Temporal Resolution ◽  
Trace Gases ◽  
Mobile Laboratory ◽  
Flow Tube ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube

Abstract. The importance of emissions source types in urban areas has undergone significant changes over the past two decades. In particular, there has been a considerable reduction in emissions associated with road vehicles. Understanding the role played by different source sectors is important if effective air pollution control is to be achieved. Current atmospheric measurements are made at fixed monitoring sites, most of which do not include the measurement of volatile organic compounds (VOCs) and so our understanding of the temporal and spatial variation of pollutants is limited. Here we describe the application of a mobile laboratory using a selected-ion flow tube mass spectrometer (SIFT-MS) and other trace gas instrumentation to provide on-road, high spatial and temporal resolution measurements of CO2, CH4, VOCs and other trace gases. We then present data illustrating the potential of this platform for developing source characterisation methods that account for the similarity in correlation between species. Finally, we consider the benefits of high spatial and temporal resolution measurements in characterising different types of source, which would be difficult or impossible for single species studies.

Reactions of Ar+with Selected Volatile Organic Compounds. A Flowing Afterglow and Selected Ion Flow Tube Study

2000 ◽  
Vol 104 (48) ◽  
pp. 11318-11327 ◽  
Author(s):  
Michael H. Cohen ◽  
Cynthia Barckholtz ◽  
Brian T. Frink ◽  
Joshua J. Bond ◽  
C. Michael Geise ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Flow Tube ◽  
Flowing Afterglow ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube ◽  
Tube Study

COMPOSITION OF VOLATILE ORGANIC COMPOUNDS IN DIATHERMY PLUME AS DETECTED BY SELECTED ION FLOW TUBE MASS SPECTROMETRY

2007 ◽  
Vol 77 (1-2) ◽  
pp. 20-23 ◽  
Author(s):  
Andrew R. Moot ◽  
Katherine M. Ledingham ◽  
Paul F. Wilson ◽  
Senti T. Senthilmohan ◽  
David R. Lewis ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Flow Tube ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube

Selected ion flow tube mass spectrometry for targeted analysis of volatile organic compounds in human breath

2021 ◽  
Author(s):  
Ilaria Belluomo ◽  
Piers R. Boshier ◽  
Antonis Myridakis ◽  
Bhamini Vadhwana ◽  
Sheraz R. Markar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Flow Tube ◽  
Human Breath ◽  
Ion Flow ◽  
Targeted Analysis ◽  
Volatile Organic ◽  
Selected Ion Flow Tube

Release of toxic ammonia and volatile organic compounds by heated cannabis and their relation to tetrahydrocannabinol content

2015 ◽  
Vol 7 (10) ◽  
pp. 4104-4110 ◽  
Author(s):  
David Smith ◽  
Roger Bloor ◽  
Claire George ◽  
Andriy Pysanenko ◽  
Patrik Španěl
Keyword(s):  
Mass Spectrometry ◽  
Volatile Organic Compounds ◽  
Volatile Compounds ◽  
Organic Compounds ◽  
Flow Tube ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube ◽  
Commercial Device

Selected ion flow tube mass spectrometry (SIFT-MS) has been used to analyse the volatile compounds released when “street” cannabis is heated in the commercial device known as the “Volcano”.

scholarly journals The Use of Selected Ion Flow Tube-Mass Spectrometry Technology to Identify Breath Volatile Organic Compounds for the Detection of Head and Neck Squamous Cell Carcinoma: A Pilot Study

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 306 ◽  
Author(s):  
Dhinashini Chandran ◽  
Eng H. Ooi ◽  
David I Watson ◽  
Feruza Kholmurodova ◽  
Simone Jaenisch ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Squamous Cell Carcinoma ◽  
Pilot Study ◽  
Volatile Organic Compounds ◽  
Cell Carcinoma ◽  
Organic Compounds ◽  
Flow Tube ◽  
Ion Flow ◽  
Volatile Organic ◽  
Selected Ion Flow Tube

Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common form of cancer worldwide, with approximately 630,000 new cases diagnosed each year. The development of low-cost and non-invasive tools for the detection of HNSCC using volatile organic compounds (VOCs) in the breath could potentially improve patient care. The aim of this study was to investigate the feasibility of selected ion flow tube mass spectrometry (SIFT-MS) technology to identify breath VOCs for the detection of HNSCC. Materials and Methods: Breath samples were obtained from HNSCC patients (N = 23) and healthy volunteers (N = 21). Exhaled alveolar breath samples were collected into FlexFoil® PLUS (SKC Limited, Dorset, UK) sampling bags from newly diagnosed, histologically confirmed, untreated patients with HNSCC and from non-cancer participants. Breath samples were analyzed by Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS) (Syft Technologies, Christchurch, New Zealand) using Selective Ion Mode (SIM) scans that probed for 91 specific VOCs that had been previously reported as breath biomarkers of HNSCC and other malignancies. Results: Of the 91 compounds analyzed, the median concentration of hydrogen cyanide (HCN) was significantly higher in the HNSCC group (2.5 ppb, 1.6–4.4) compared to the non-cancer group (1.1 ppb, 0.9–1.3; Benjamini–Hochberg adjusted p < 0.05). A receiver operating curve (ROC) analysis showed an area under the curve (AUC) of 0.801 (95% CI, 0.65952–0.94296), suggesting moderate accuracy of HCN in distinguishing HNSCC from non-cancer individuals. There were no statistically significant differences in the concentrations of the other compounds of interest that were analyzed. Conclusions: This pilot study demonstrated the feasibility of SIFT-MS technology to identify VOCs for the detection of HNSCC.

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