Abstract
Purpose: We aimed to assess the relationship between lifestyle-related variables, metabolic syndrome, and lower urinary tract symptoms (LUTS) in men ≥40years. We also assessed the impact of these variables on quality of life. Materials and methods: From 2014 to 2020, 5,355 men who underwent health check-ups with I-PSS questionnaires at our institute were included in the analysis. The impact of LUTS on sleep disorders and moderate to severe degrees of stress were assessed. Multivariate analysis was performed to determine the variables associated with LUTS and prostate volume. Results: Moderate and severe LUTS were present in 1,317 (24.6%) and 211 (3.9%) men, respectively. Moderate and severe LUTS were significantly associated with the presence of sleep disorders and stress. On multivariable analysis, age, amount of life-long smoking, marital status, income, job, and decreased HDL-cholesterol were associated with the presence of moderate to severe LUTS. Central obesity and decreased HDL-cholesterol levels were also significantly associated with prostate volume, in addition to age. Conclusions: In men ≥40years, stable socioeconomic status is negatively associated with moderate to severe LUTS, which worsens sleep quality and stress level. In addition, quitting smoking and maintaining HDL-cholesterol over 40mg/dL might be effective for preventing moderate to severe LUTS.