Loratadine syrup is successfully used to fix Covid-19 induced respiratory distress and chest pain

COVID-19 disease is a highly transmissible viral infection caused by the SARS-CoV-2 coronavirus. This virus can cause lung damage, acute respiratory distress syndrome and death. In this case, How Covid-19 in a pregnant patient which didn’t respond well to Vancomyci + Caftazidime + Dexamethasone + Heparin for 7 days was finally responded to Loratadine syrup, and the patient was cured is going to be presented.

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Nitric oxide and interval hypoxic training in COVID-19 rehabilitation— new research direction

Fizioterapevt (Physiotherapist) ◽

10.33920/med-14-2108-04 ◽

2021 ◽

pp. 30-41

Author(s):

Tatyana Nikolaevna Tsyganova ◽

Egor Egorov ◽

Tamara Nikolaevna Voronina

Keyword(s):

Nitric Oxide ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Viral Infection ◽

Distress Syndrome ◽

The Body ◽

Lung Damage ◽

Specific Method ◽

Hypoxic Training

COVID-19, a disease caused by the novel coronavirus SARS-CoV-2, primarily affects lung tissue and disrupts gas exchange, leading to acute respiratory distress syndrome, systemic hypoxia, and lung damage. The search for methods of prevention and rehabilitation, especially after suffering from pneumonia caused by COVID-19, is on the agenda. This article discusses the possibilities of the interval hypoxic training (IHT) method for preventing infections by initiating nitric oxide production in the body. One of the main effects of IHT is the balanced stimulation of nitric oxide (NO) secretion. Over the past two decades, there has been an increasing interest in the function of nitric oxide (NO) in the human body. Nitric oxide plays a key role in maintaining normal vascular function and regulating inflammatory processes, including those leading to lung damage and the development of acute respiratory distress syndrome (ARDS). Our immune system destroys bacteria and viruses by oxidative burst, i.e. when oxygen accumulates inside the cell. This process also involves nitric oxide, a signaling molecule that has an antibacterial and antiviral effect, as well as regulates vascular tone and affects the permeability of the cell wall. Interval hypoxytherapy enhances endogenous oxidative protection and increases the amount of nitric oxide, thus allowing the body’s cells to resist infection more effectively. Mitochondrial NOS induction and mitochondrial NO synthesis increase under the action of pathogenic factors on the cell. By modulating the activity of mtNOS and the synthesis of mitochondrial NO, it is possible to increase the resistance to hypoxic effects. Interval hypo-hyperoxic training as an effective non-specific method of increasing the body’s defenses is indispensable not only in the prevention of viral infection, but also in rehabilitation after viral pneumonia, as well as as a method that reduces the severity of viral infection in the event of infection.

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Prone ventilation in a pregnant patient with scrub typhus-induced acute respiratory distress syndrome

BMJ Case Reports ◽

10.1136/bcr-2021-242870 ◽

2021 ◽

Vol 14 (4) ◽

pp. e242870

Author(s):

Meenupriya Arasu ◽

Nagalakshmi Swaminathan ◽

Anusha Cherian ◽

Magesh Parthiban

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Scrub Typhus ◽

Febrile Illness ◽

Pregnant Patient ◽

Lung Compliance ◽

Pcr Assay ◽

Oxygenation Indices

A 23-year-old primigravida at 20 weeks of gestation presented to our hospital with undifferentiated febrile illness and severe acute respiratory distress syndrome. She was intubated in the emergency department and transferred to the intensive care unit. Initial treatment included ventilatory care, vasopressor support and broad-spectrum antibiotics. Based on a positive PCR assay for scrub typhus, she was treated with intravenous doxycycline and azithromycin. Despite reduction in fever, her oxygenation further declined. Following a risk–benefits assessment, we decided to ventilate her in prone position for 8 hours a day for three consecutive days using a checklist-based protocol. Her oxygenation indices and lung compliance markedly improved over this period, and she was extubated a day later. She was eventually discharged home after 1 week.

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Acute respiratory distress syndrome: An unusual presentation of chikungunya fever viral infection

Journal of Global Infectious Diseases ◽

10.4103/0974-777x.194374 ◽

2017 ◽

Vol 9 (1) ◽

pp. 33 ◽

Cited By ~ 1

Author(s):

Abhijeet Singh

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Viral Infection ◽

Distress Syndrome ◽

Unusual Presentation ◽

Chikungunya Fever

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Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

Cannabis and Cannabinoid Research ◽

10.1089/can.2020.0043 ◽

2020 ◽

Vol 5 (3) ◽

pp. 197-201 ◽

Cited By ~ 3

Author(s):

Hesam Khodadadi ◽

Évila Lopes Salles ◽

Abbas Jarrahi ◽

Fairouz Chibane ◽

Vincenzo Costigliola ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Viral Infection ◽

Distress Syndrome ◽

Cytokine Storm

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Sevoflurane, Compared With Isoflurane, Minimizes Lung Damage in Pulmonary but Not in Extrapulmonary Acute Respiratory Distress Syndrome in Rats

Anesthesia & Analgesia ◽

10.1213/ane.0000000000001927 ◽

2017 ◽

Vol 125 (2) ◽

pp. 491-498 ◽

Cited By ~ 1

Author(s):

Mariana N. Araújo ◽

Cíntia L. Santos ◽

Cynthia S. Samary ◽

Luciana B. B. Heil ◽

Vinicius C. M. Cavalcanti ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Lung Damage

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Protective - ventilation strategy in the acute respiratory distress syndrome

Acta chirurgica iugoslavica ◽

10.2298/aci0403045b ◽

2004 ◽

Vol 51 (3) ◽

pp. 45-49 ◽

Cited By ~ 1

Author(s):

Vladimir Bumbasirevic ◽

V. Bukumirovic ◽

Nada Popovic ◽

V. Nikolic ◽

Nevena Kalezic ◽

...

Keyword(s):

Mechanical Ventilation ◽

Acute Respiratory Distress Syndrome ◽

Lung Injury ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Pulmonary Ventilation ◽

Lung Damage ◽

Ventilatory Strategy ◽

Protective Ventilation Strategy

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) contribute to progressive hypoxemia in critically ill patients. It has been proved that conventional mechanical ventilation with physiological respiratory volume contributes to further lung damage. In this respect, application of protective ventilatory strategy - pulmonary ventilation with limited volume and pressure can avoid mentioned consequences. The aim of this paper is to discuss mechanims by which elements contained in protective mechanical ventilation of patients with ALI/ARDS prevent further progrssive lung injury, to argue the effects of positive end - expiratory pressure and present insturctions for its application.

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Impact of Ventilator-Subject Asynchrony on the Work of Breathing and Lung Damage in Experimental Acute Respiratory Distress Syndrome

10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1136 ◽

2019 ◽

Author(s):

J.J.M. Wittenstein ◽

M. Scharffenberg ◽

R. Huhle ◽

T. Bluth ◽

M. Leidermann ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Work Of Breathing ◽

Lung Damage

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EXTRACORPOREAL MEMBRANE OXYGENATION APPLICATION IN PREGNANT PATIENT WITH UROSEPSIS ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME - A CASE REPORT

Respirology ◽

10.1111/resp.13420_156 ◽

2018 ◽

Vol 23 ◽

pp. 147-147

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Case Report ◽

Extracorporeal Membrane Oxygenation ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Pregnant Patient ◽

Membrane Oxygenation

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Recovery of COVID-19 acute respiratory distress syndrome with tocilizumab: successful outcome in two critically ill patients

Immunotherapy ◽

10.2217/imt-2020-0154 ◽

2020 ◽

Vol 12 (15) ◽

pp. 1127-1132 ◽

Cited By ~ 4

Author(s):

Juan David Cala-García ◽

Juan David Sierra-Bretón ◽

Jorge Eduardo Cavelier-Baiz ◽

Álvaro A Faccini-Martínez ◽

Carlos Eduardo Pérez-Díaz

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Severe Pneumonia ◽

Lung Damage ◽

Successful Outcome ◽

Cytokine Storm ◽

Principal Mechanism ◽

Prior Administration

Background: Severe pneumonia and acute respiratory distress syndrome (ARDS) due to COVID-19 is a challenge for nowadays medical practice. Although there is no clarity in the principal mechanism of lung damage and ARDS development, it has been suggested that one of the main reasons of this pathology is the hyperactivation of the immune system, better known as cytokine storm syndrome. Tocilizumab has been proposed to treat COVID-19 severe cases associated to ARDS. Results & methodology: Here we present two successful cases of tocilizumab administration in two COVID-19 patients with prior administration of antiviral therapy (hydroxychloroquine, azithromycin, lopinavir and ritonavir) with adequate response and resolution of ARDS, septic shock and severe pneumonia within the first 72 h. Discussion & conclusion: This case supports the usage of tocilizumab as an effective therapy in COVID-19 associated cytokine storm syndrome. Further studies should be done in order to assess its effectiveness and security.

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