scholarly journals Multifocal Toxoplasma Retinochoroiditis in a Nonimmunosuppressed Elderly Patient: Case Report and Brief Review of the Literature

2017 ◽  
Vol 1 (1) ◽  
pp. oapoc.0000023
Author(s):  
David A. Kilgore ◽  
Sami Uwaydat ◽  
Stephen Davis ◽  
Harry Brown ◽  
Ahmed B. Sallam
Keyword(s):  
Case Report ◽  
Elderly Patients ◽  
Review Of The Literature ◽  
Chain Reaction ◽  
Patient Case ◽  
Diagnostic Challenge ◽  
Chorioretinal Biopsy ◽  
Polymerase Chain ◽  
Fundus Photographs ◽  
Vitreous Haze

Purpose To raise awareness of ophthalmologists that toxoplasmosis should be considered in the differential diagnosis of multifocal or diffuse necrotizing retinitis in nonimmunosuppressed elderly patients. Methods Interventional case report with serial color fundus photographs, indocyanine green angiography, fluorescein angiography, optical coherence tomography, and chorioretinal biopsy histology. Results A 77-year-old, nonimmunosuppressed man developed extensive multifocal retinochoroiditis with scattered focal hemorrhages and significant vitreous haze. This case posed a significant diagnostic challenge mimicking viral retinitis. Vitreous polymerase chain reaction and chorioretinal biopsy confirmed the diagnosis of toxoplasma retinochoroiditis. Conclusions As demonstrated in this case, toxoplasmosis should be considered as a cause of multifocal and/or diffuse necrotizing retinitis in elderly patients even in the absence of obvious systemic immunosuppression.

scholarly journals Plague in a Pediatric Patient: Case Report and Use of Polymerase Chain Reaction as a Diagnostic Aid

2014 ◽  
Vol 3 (4) ◽  
pp. e38-e41 ◽  
Author(s):  
W. K. Drummond ◽  
C. A. Nelson ◽  
J. Fowler ◽  
E. E. Epson ◽  
P. S. Mead ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Case Report ◽  
Pediatric Patient ◽  
Chain Reaction ◽  
Patient Case ◽  
Diagnostic Aid ◽  
Polymerase Chain

Angiocentric Glioma in an Elderly Patient: Case Report and Review of the Literature

2017 ◽  
Vol 97 ◽  
pp. 755.e5-755.e10 ◽  
Author(s):  
Lain Hermes Gonzalez-Quarante ◽  
Carlos Fernández Carballal ◽  
Vijay Agarwal ◽  
Antonio J. Vargas Lopez ◽  
Oscar Lucas Gil de Sagredo del Corral ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Review Of The Literature ◽  
Patient Case ◽  
Angiocentric Glioma

scholarly journals Chronic Invasive Fungal Sinusitis With Negative Histopathology: A Diagnostic Challenge

2021 ◽  
pp. 014556132097377
Author(s):  
Anne Ning ◽  
Arminé Kocharyan ◽  
W Colby Brown ◽  
Brian D’Anza
Keyword(s):  
Definitive Diagnosis ◽  
Fungal Sinusitis ◽  
Chain Reaction ◽  
Diagnostic Challenge ◽  
Invasive Fungal Sinusitis ◽  
Fungal Organisms ◽  
Fungal Dna ◽  
Polymerase Chain ◽  
Histopathologic Findings ◽  
Chronic Invasive

Although the diagnosis of chronic invasive fungal sinusitis relies chiefly on identification of invasive fungi on histology, the insidious nature of the disease can preclude detection of fungal organisms. Here, we present a case of chronic invasive fungal sinusitis with negative histopathologic findings and a definitive diagnosis made through fungal DNA detection. Clinicians should consider polymerase chain reaction an important complement to histology and culture in the diagnosis of chronic invasive fungal sinusitis.

Case Report: Progressive Dysphonia and Dysphagia due to Laryngeal Leishmaniasis

2021 ◽  
Author(s):  
Laura Renard ◽  
Adrien Lemaignen ◽  
Guillaume Desoubeaux ◽  
David Bakhos
Keyword(s):  
Polymerase Chain Reaction ◽  
Weight Loss ◽  
Case Report ◽  
Amphotericin B ◽  
Laryngeal Cancer ◽  
Complete Resolution ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Histopathology Examination

Laryngeal leishmaniasis is an unusual form of the disease. We report the case of a patient who consulted for dysphonia and dysphagia in a context of asthenia and weight loss. The patient had lesions that were suggestive of laryngeal cancer but were revealed to be leishmaniasis by histopathology examination and polymerase chain reaction. Treatment with amphotericin B and miltefosine permitted complete resolution of the lesions and no recurrence during the 18-month follow-up period.

scholarly journals Near-fatal presentation of bilateral pneumothorax in cutis laxa patient: Case report, and review of the literature

2018 ◽  
Vol 13 (4) ◽  
pp. 254 ◽  
Author(s):  
WaseemM Hajjar ◽  
AreejS Alrajeh ◽  
LulwahS Alturki ◽  
SamiA Al-Nassar ◽  
AdnanW Hajjar
Keyword(s):  
Case Report ◽  
Cutis Laxa ◽  
Review Of The Literature ◽  
Patient Case ◽  
Bilateral Pneumothorax

scholarly journals Urachal yolk sac tumor penetrating the bladder as a diagnostic challenge: a case report and review of the literature

2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Vladimír Šámal ◽  
Tomáš Jirásek ◽  
Vít Paldus ◽  
Igor Richter ◽  
Ondřej Hes
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Review Of The Literature ◽  
Diagnostic Challenge ◽  
Macroscopic Hematuria ◽  
Rare Case Report

Abstract Background Yolk sac tumor (YST) is a germ cell tumor. It is primarily located in the gonads but can also occur extragonadally (extragonadal yolk sac tumor - EGYST), most commonly in the pelvis, retroperitoneum or mediastinum. Only a few YSTs of the urachus have been described. Case report We present a rare case report of a 37-year-old male with episodes of macroscopic hematuria. The histological specimen obtained by transurethral resection showed a solid, and in some parts papillary infiltrative, high-grade tumor with numerous areas of marked nuclear atypia and clear invasion between the detrusor bundles. Glandular pattern has been observed in only minority of the tumor. Immunohistochemistry showed significant positivity for GPC3, SALL4 and cytokeratins AE1/AE3, while KRT7 and GATA3 were negative. We concluded that the biopsy findings were consistent with urothelial carcinoma with infrequent YST differentiation. In definitive surgical specimens we found a malignant epithelial, glandular and cystically arranged tumor of germinal appearance arising from urachus. The surrounding urothelium was free of invasive or in situ tumor changes. We reclassified the tumor as a urachal YST. Conclusion EGYST was suspected because glandular and hepatoid structures were found, but the presence of these structures should be verified by immunohistochemistry.

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