Visible light-triggered drug release for cancer therapy

A multifunctional drug delivery system with AIE character was designed and constructed for simultaneous cellular imaging and pH-triggered drug release.

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Visible-Light-Triggered Drug Release from TiO2 Nanotube Arrays: A Controllable Antibacterial Platform

Angewandte Chemie ◽

10.1002/ange.201508710 ◽

2015 ◽

Vol 128 (2) ◽

pp. 603-607 ◽

Cited By ~ 17

Author(s):

Jingwen Xu ◽

Xuemei Zhou ◽

Zhida Gao ◽

Yan-Yan Song ◽

Patrik Schmuki

Keyword(s):

Drug Release ◽

Visible Light ◽

Tio2 Nanotube Arrays ◽

Tio2 Nanotube ◽

Nanotube Arrays ◽

Triggered Drug Release

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Click and photo-unclick chemistry of aminoacrylate for visible light-triggered drug release

Chemical Communications ◽

10.1039/c2cc32373g ◽

2012 ◽

Vol 48 (52) ◽

pp. 6517 ◽

Cited By ~ 57

Author(s):

Moses Bio ◽

Gregory Nkepang ◽

Youngjae You

Keyword(s):

Drug Release ◽

Visible Light ◽

Triggered Drug Release

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Dual-triggered drug-release vehicles for synergistic cancer therapy

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2018.10.043 ◽

2019 ◽

Vol 173 ◽

pp. 788-797 ◽

Cited By ~ 6

Author(s):

Ting-Yu Tu ◽

Shu-Jyuan Yang ◽

Ming-Hsien Tsai ◽

Chung-Hao Wang ◽

Shin-Yu Lee ◽

...

Keyword(s):

Cancer Therapy ◽

Drug Release ◽

Triggered Drug Release

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Near-infrared laser-triggered drug release in tellurium nanosystem for simultaneous chemo-photothermal cancer therapy

Biomaterials Science ◽

10.1039/d0bm01811b ◽

2021 ◽

Author(s):

Linqi Duan ◽

Ting Liu ◽

Tianfeng Chen

Keyword(s):

Cancer Therapy ◽

Drug Release ◽

Tumor Cells ◽

Clinical Application ◽

Near Infrared ◽

Infrared Laser ◽

Normal Cells ◽

Triggered Drug Release

Tumor cells can be selectively killed by the different tolerance of normal cells and tumor cells to temperature. However, the limited clinical application of PTT is mainly due to various...

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Gold Nanocage-Incorporated Poly(ε-Caprolactone) (PCL) Fibers for Chemophotothermal Synergistic Cancer Therapy

Pharmaceutics ◽

10.3390/pharmaceutics11020060 ◽

2019 ◽

Vol 11 (2) ◽

pp. 60 ◽

Cited By ~ 5

Author(s):

Ju Park ◽

Hojun Seo ◽

Da Kim ◽

Ji Choi ◽

Jin Son ◽

...

Keyword(s):

Fatty Acid ◽

Cancer Therapy ◽

Drug Release ◽

Near Infrared ◽

Hyperthermia Treatment ◽

Anticancer Efficacy ◽

Drug Molecules ◽

Nir Light ◽

Rapid Release ◽

Triggered Drug Release

This paper introduces a new fibrous system for synergistic cancer therapy, which consists of gold nanocage (AuNC)-loaded poly(ε-caprolactone) (PCL) fibers with encapsulation of a chemotherapeutic anticancer drug in their core and loading of a phase-changeable fatty acid in their sheath. Under on–off switching of near-infrared (NIR) light irradiation, the excellent photothermal ability and photostability of AuNCs allows repeated, significant heating of the fibers to a temperature available to hyperthermia. Simultaneously, the NIR light-induced heat generation enables the melting out of the loaded fatty acid, leading to a rapid release of the drug molecules from the fibers. The combination of this NIR light-triggered drug release with the repeated hyperthermia treatment exhibits excellent anticancer efficacy.

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Reduction-active polymeric prodrug micelles based on α-cyclodextrin polyrotaxanes for triggered drug release and enhanced cancer therapy

Carbohydrate Polymers ◽

10.1016/j.carbpol.2018.03.097 ◽

2018 ◽

Vol 193 ◽

pp. 153-162 ◽

Cited By ~ 18

Author(s):

Shuang Bai ◽

Meili Hou ◽

Xiaoxiao Shi ◽

Jiucun Chen ◽

Xiaoqian Ma ◽

...

Keyword(s):

Cancer Therapy ◽

Drug Release ◽

Polymeric Prodrug ◽

Triggered Drug Release

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Comb-like poly(l-cysteine) derivatives with different side groups: synthesis via photochemistry and click chemistry, multi-responsive nanostructures, triggered drug release and cytotoxicity

Polymer Chemistry ◽

10.1039/c5py01113b ◽

2015 ◽

Vol 6 (38) ◽

pp. 6857-6869 ◽

Cited By ~ 23

Author(s):

Xingjie Wu ◽

Linzhu Zhou ◽

Yue Su ◽

Chang-Ming Dong

Keyword(s):

Cancer Therapy ◽

Drug Release ◽

Click Chemistry ◽

On Demand ◽

Triggered Drug Release ◽

Ene Addition

A series of comb-like graft polypeptides having different side groups and tunable grafting ratios were prepared by sequential photocleavage reactions and Michael-type thiol–ene addition, which provides a promising platform for on-demand nanomedicine and cancer therapy.

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