scholarly journals Exposure Assessment and Human Biological Monitoring in Risk Assessment

2020 ◽  
Vol 25 (11) ◽  
pp. 11_74-11_79
Author(s):  
Hiroshi SATOH
2020 ◽  
Vol 72 (12) ◽  
pp. 62-63
Author(s):  
Chris Carpenter

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 199412, “New Produced-Water Risk-Based-Approach Guidance,” by Mathijs Smit, Shell; Sean Hayes, More Energy; and Oliver Pelz, BP, et al., for the 2020 SPE International Conference and Exhibition on Health, Safety, Environment, and Sustainability, originally scheduled to be held in Bogota, Colombia, 17-19 March. The paper has not been peer reviewed. A global trend has developed toward the application of risk- based assessment (RBA) techniques for managing environmental risks and considering potential effects of produced-water (PW) discharge. The main objective of the complete paper is to achieve harmony in the means by which operators execute RBA for offshore PW discharges. This coordination is likely to enhance broader understanding and acceptance of RBA techniques internationally. RBA Techniques Key Principles. An RBA approach to managing PW begins with an assessment objective (e.g., demonstrating no adverse effect outside an accepted zone). The RBA characterizes the risk (i.e., the likelihood that adverse effects may occur) to the environment of a PW discharge given the exposure resulting from effluent discharge and the sensitivity of the receiving environment to exposure. To assess the risks of discharge, existing international frameworks for ecological risk assessment are available. These frameworks include data collection, hazard assessment, exposure assessment, and risk characterization. The specifics of data collection depend on the form of the hazard assessment and the exposure assessment, which, in turn, are dependent on the risk characterization, which allows compliance with the assessment objective to be evaluated. The purpose of the RBA for PW can be to target no adverse effect beyond an accepted zone or to serve as a management tool to drive continuous improvement. The risk-assessment steps usually are executed through a tiered process. Regulatory Approaches to RBA. At the time of writing, only a handful of regulatory frameworks for offshore PW management include principles of RBA. Table 1 of the complete paper provides a comparison of different assessment objectives and endpoints for regulatory PW RBA approaches used in selected basins. The table makes clear that it is not practical or necessary to meet the required criteria at the end of the pipe. Common practice defines a zone where the defined threshold may still be exceeded. This zone is often referred to as the mixing zone. While the use of a 500-m mixing zone is common practice offshore Brazil, for instance, in the US Gulf of Mexico, a 100-m mixing zone is applied. Different thresholds are applied in the different jurisdictions that justify the mixing zones. Defining the Adverse Effect Threshold. The three regulatory approaches presented in Table 1 of the complete paper apply different methodologies for defining the threshold level of adverse effects that should not be exceeded.


2014 ◽  
Vol 32 (No. 2) ◽  
pp. 122-131 ◽  
Author(s):  
P. Ačai ◽  
Ľ. Valík ◽  
D. Liptáková

Quantitative risk assessment of Bacillus cereus using data from pasteurised milk produced in Slovakia was performed. Monte Carlo simulations were used for probability calculation of B. cereus density at the time of pasteurised milk consumption for several different scenarios. The results of the general case exposure assessment indicated that almost 14% of cartons can contain &gt; 10<sup>4</sup> CFU/ml of B. cereus at the time of pasteurised milk consumption. Despite the absence of a generally applicable dose-response relationship that limits a full risk assessment, the probability of intoxication per serving and the estimated number of cases in the population were calculated for the general exposure assessment scenario using an exponential dose-response model based on Slovak data. The mean number of annual cases provided by the risk assessment model for pasteurised milk produced in Slovakia was 0.054/100 000 population. In comparison, the overall reporting rate of the outbreaks in the EU in which B. cereus toxins were the causative agent was 0.02/100 000 population in 2010. Our assessment is in accordance with a generally accepted fact that reporting data for alimentary intoxication are underestimated, mostly due to the short duration of the illness. &nbsp;


2009 ◽  
Vol 72 (2) ◽  
pp. 425-427 ◽  
Author(s):  
KONSTANTINOS KOUTSOUMANIS

In this study, I describe a systematic approach for modeling food spoilage in microbial risk assessment that is based on the incorporation of kinetic spoilage modeling in exposure assessment by combining data and models for the specific spoilage organisms (SSO: fraction of the total microflora responsible for spoilage) with those for pathogens. The structure of the approach is presented through an exposure assessment application for Escherichia coli O157:H7 in ground beef. The proposed approach allows for identifying spoiled products at the time of consumption by comparing the estimated level of SSO (pseudomonads) with the spoilage level (level of SSO at which spoilage is observed). The results of the application indicate that ignoring spoilage in risk assessment could lead to significant overestimations of risk.


Author(s):  
Morton Lippmann ◽  
Richard B. Schlesinger

This chapter describes the characterization of occupational exposures of workers to chemicals at their job sites, and exposures of general populations to chemicals in the environmental for individuals and population groups. It also discusses: approaches to risk assessment; the determination of whether exposures exceed established exposure limits or standards; and the methodologies used to determine and/or model the concentrations of chemicals in environmental media that are used to determine the nature and extent of exposures, and of biomarkers of exposure, to individuals and populations of humans and other receptors.


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