scholarly journals CHALLENGING COVID-19

INDIAN DRUGS ◽  
2020 ◽  
Vol 57 (02) ◽  
pp. 5-6
Author(s):  
Nagaraj N. Rao ◽  
Keyword(s):  
Middle East ◽  
Respiratory Tract ◽  
Large Family ◽  
Upper Respiratory Tract ◽  
Dromedary Camels ◽  
Zoonotic Viruses ◽  
Respiratory Tract Illnesses ◽  
Dear Reader ◽  
Upper Respiratory ◽  
Human Coronaviruses

Dear Reader, Coronaviruses are a large family of zoonotic viruses, that is, the virus is transmitted from animals to humans. Although several common human coronaviruses are known, and usually lead upon infection to mild to moderate upper-respiratory tract illnesses, some coronaviruses cause epidemics. Severe Acute Respratory Syndrome (SARS-CoV) erupted in February 2003 following transmission from civet cats to humans. Middle East Respiratory Syndrome (MERS-CoV) surfaced in April 2012 following transmission from dromedary camels to humans. However, both these epidemics pale into insignificance in the context of the havoc currently being caused by an hitherto unknown coronavirus, now named as COVID-19 and which is first assumed to have started mid-December 2019 in Wuhan, China. It is strongly suspected that COVID-19 was transmitted from bats to humans.

scholarly journals Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels

2016 ◽  
Vol 90 (9) ◽  
pp. 4838-4842 ◽  
Author(s):  
W. Widagdo ◽  
V. Stalin Raj ◽  
Debby Schipper ◽  
Kimberley Kolijn ◽  
Geert J. L. H. van Leenders ◽  
...  
Keyword(s):  
Middle East ◽  
Respiratory Tract ◽  
Differential Expression ◽  
Dipeptidyl Peptidase ◽  
Middle East Respiratory Syndrome ◽  
Upper Respiratory Tract ◽  
Dromedary Camels ◽  
Dipeptidyl Peptidase 4 ◽  
Upper Respiratory

Middle East respiratory syndrome coronavirus (MERS-CoV) is not efficiently transmitted between humans, but it is highly prevalent in dromedary camels. Here we report that the MERS-CoV receptor—dipeptidyl peptidase 4 (DPP4)—is expressed in the upper respiratory tract epithelium of camels but not in that of humans. Lack of DPP4 expression may be the primary cause of limited MERS-CoV replication in the human upper respiratory tract and hence restrict transmission.

Upper respiratory tract illnesses and accidents

1994 ◽  
Vol 44 (3) ◽  
pp. 141-144 ◽  
Author(s):  
A. P. Smith ◽  
I. Harvey ◽  
P. Richmond ◽  
T. J. Peters ◽  
M. Thomas ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Respiratory Tract Illnesses ◽  
Upper Respiratory

Historical Insight, Classification, and Common Features of Coronavirus Family

2022 ◽  
pp. 1-20
Author(s):  
Moulay Abdelmonaim El Hidan ◽  
Soraia El Baz ◽  
Mohamed Merzouki ◽  
Kholoud Kahime ◽  
Moulay Abdeljalil Ait Baamrane ◽  
...  
Keyword(s):  
Large Family ◽  
Upper Respiratory Tract ◽  
Virus Family ◽  
Respiratory Tract Illnesses ◽  
History Of ◽  
The Common ◽  
Upper Respiratory ◽  
Novel Coronavirus ◽  
Viral Surface

Coronaviruses are a large family of viruses that usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. They were named according to the shape of glycoprotein spikes present on the viral surface and resembling to the solar corona. The first coronaviruses identified in human were HCoV 229E and the HCoV OC43, known also as β-coronavirus. This virus family has become increasingly important and received more attention within scientific community in the past two decades because of three new viruses that can cause serious, even fatal, disease. These are SARS coronavirus (SARS-CoV), which emerged in November 2002 and caused severe acute respiratory syndrome (SARS); Middle East respiratory syndrome (MERS) caused by the MERS coronavirus (MERS-CoV), identified in September 2012 and continues to cause sporadic and localized outbreaks. The third novel coronavirus to emerge in this century is called SARS-CoV-2. This chapter will describe the history of the coronavirus family discovery, emergence, and classification of the main coronaviruses.

scholarly journals MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013–2014

2015 ◽  
Vol 21 (7) ◽  
pp. 1153-1158 ◽  
Author(s):  
Abdelmalik I. Khalafalla ◽  
Xiaoyan Lu ◽  
Abdullah I.A. Al-Mubarak ◽  
Abdul Hafeed S. Dalab ◽  
Khalid A.S. Al-Busadah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Dromedary Camels ◽  
Upper Respiratory

scholarly journals Diversity and Evolutionary Histories of Human Coronaviruses NL63 and 229E Associated with Acute Upper Respiratory Tract Symptoms in Kuala Lumpur, Malaysia

2016 ◽  
Vol 94 (5) ◽  
pp. 1058-1064 ◽  
Author(s):  
Maryam Nabiel Al-Khannaq ◽  
Yutaka Takebe ◽  
Yong Kek Pang ◽  
Xiang Yong Oong ◽  
Kok Keng Tee ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Kuala Lumpur ◽  
Upper Respiratory ◽  
Human Coronaviruses
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