DERIVITISATION OF PREGABALIN FOR SIMULTANEOUS ESTIMATION WITH METHYLCOBALAMINE USING ULTRAVIOLET SPECTROSCOPY
Keyword(s):
Accurate, sensitive, and economical procedures for simultaneous estimation of pregabalin and methylcobalamine in tablet dosage form have been developed. The method employed is simultaneous equation method. This method employs the formation and solving of simultaneous equation using 528 nm and 568 nm as the two wavelengths for forming equation. Drugs obey Beer’s law in the concentration range 10-50 µg mL-1 for pregabalin and 10-50 µg mL-1 for methylcobalamine. The proposed spectrophotometric method was validated and successfully applied for the assay of both drug combinations in several laboratory prepared mixtures and commercial tablets
2014 ◽
Vol 2014
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pp. 1-8
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2014 ◽
Vol 2014
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pp. 1-6
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2016 ◽
Vol 1
(02)
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pp. 56-59
2018 ◽
Vol 1
(3)
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pp. 19-23
2017 ◽
Vol 8
(03)
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2019 ◽
Vol 12
(4)
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pp. 35-42