scholarly journals Urethral dysontogenic metaplasia in cat with bilateral renal dysplasia

2017 ◽  
Vol 38 (5) ◽  
pp. 3383
Author(s):  
Carolina Da Fonseca Sapin ◽  
Luisa Mariano Cerqueira da Silva ◽  
Haide Valeska Scheid ◽  
Ceres Cristina Tempel Nakasu ◽  
Marlete Brum Cleff ◽  
...  

This paper to describe a case of dysontogenic urethral metaplasia in a one month old mongrel feline who also had bilateral renal dysplasia. Dysontogenic metaplasia in cats are scarce and this change may be associated with renal dysplasia and/or lower urinary tract. The animal had history of abdominal enlargement since birth and dysuria, eliminating urine only dropwise. Due to the poor prognosis we opted for euthanasia. At necropsy was observed enlarged and distended bladder, reduced kidneys and dilated and tortuous ureters. The urethra was thickened, hard to cut, and histologically, was replacing the connective tissue, cartilage and endochondral ossification areas, which features dysontogenic metaplasia. Both kidneys presented primitive appearance featuring dysplasia. Dysontogenic metaplasia in urinary tract feline with renal dysplasia, has not been described.

2020 ◽  
Vol 13 (12) ◽  
pp. e236280
Author(s):  
Ayesha Nusrat ◽  
Syed Muhammad Nazim

Malignant lymphomas of the prostate are very rare tumours and are generally not considered in the clinical or pathological diagnosis of prostatic enlargement. We report a case of a 56-year-old man who presented with long-standing history of low back pain and a 2-month history of voiding lower urinary tract symptoms. He denied any history of urinary retention, trauma, catheterisation or any constitutional symptoms. Examination revealed no lymphadenopathy and hepatosplenomegaly. Digital rectal examination showed an irregular, moderately enlarged nodular prostate. His prostate-specific antigen was 1.54 ng/mL. MRI of the pelvis did not show any focal lesion apart from abnormal signal intensity in the central zone. Bone scan was negative. Transrectal ultrasound-guided prostate biopsy revealed diffuse large B cell lymphoma. Bone marrow biopsy and whole body positron emission tomography/CT were unremarkable. The patient achieved complete remission after receiving six cycles of R-CHOP chemotherapy.


2018 ◽  
Vol 315 (5) ◽  
pp. F1422-F1429 ◽  
Author(s):  
Warren G. Hill ◽  
Mark L. Zeidel ◽  
Dale E. Bjorling ◽  
Chad M. Vezina

Investigators have for decades used mouse voiding patterns as end points for studying behavioral biology. It is only recently that mouse voiding patterns were adopted for study of lower urinary tract physiology. The spontaneous void spot assay (VSA), a popular micturition assessment tool, involves placing a mouse in an enclosure lined by filter paper and quantifying the resulting urine spot pattern. The VSA has advantages of being inexpensive and noninvasive, but some investigators challenge its ability to distinguish lower urinary tract function from behavioral voiding. A consensus group of investigators who regularly use the VSA was established by the National Institutes of Health in 2015 to address the strengths and weaknesses of the assay, determine whether it can be standardized across laboratories, and determine whether it can be used as a surrogate for evaluating urinary function. Here we leverage experience from the consensus group to review the history of the VSA and its uses, summarize experiments to optimize assay design for urinary physiology assessment, and make best practice recommendations for performing the assay and analyzing its results.


2019 ◽  
Vol 101 (6) ◽  
pp. e139-e141
Author(s):  
S Chen ◽  
X Su ◽  
M Jiang ◽  
H Mi

Urethral diverticulum is a condition where the urethra or the periurethral glands push into the connective tissue layers that surround it. Patients of urethral diverticulum present with nonspecific symptoms such as incontinence, urinary frequency and urgency, and pain during sexual intercourse and urination. The incidence of this condition is low. We report a case of giant anterior urethra stones combined with a diverticulum with no lower urinary tract symptoms. We believe that this case is extremely rare, and the process of diagnosis and treatment is of great significance in clinical practice.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M Breish ◽  
C Harding ◽  
S Biswas

Abstract Aim Urodynamic studies (UDS) are physiological measurements of voiding and storage function of the lower urinary tract that are commonly performed in clinical practice to investigate bothersome lower urinary tract symptoms. Despite considerable efforts to improve UDS, standardisation of the practice remains to be challenging. This audit thus, presents a review the current UDS referral process and analysis of the clinical details included on urodynamic requests. Method This audit included retrospective data from 112 patients between March and Oct 2020, 98 of which had UDS performed. Patient electronic records, referral forms and clinic letters were all used for data collection. Results Data shows that 47% of patients were females with average age of 56 years, range (16-86) years. The reason of UDS was clearly stated in 8 referrals only and the clinical examination findings were clearly mentioned in 31% only. More than three quarters of patients (i.e., 77%) had assessment of post void residual prior to UDS, but half of the proportion had no history of relevant medications. In 98 patients who had UDS done, the main findings showed that 4 patients had normal studies, 3 with dysfunctional voiding, 7 had bladder outflow obstruction, 32 patients were diagnosed with detrusor overactivity, 12 had stress incontinence and 7 showed detrusor underactivity. Conclusions Finding of this audit clearly suggest a level of unclarity in the great majority of referrals. Evidently, key history of relevant medication is overlooked in half of the referrals. Improvements to the current pathway to UDS is therefore pivotal.


Author(s):  
Michiel F. Schreuder

Posterior urethral valves is the most common congenital cause of lower urinary tract obstruction in males, and a common cause (15–17%) for end-stage renal disease in childhood. Most commonly, posterior urethral valves is suspected on basis of a screening antenatal ultrasound. Ultrasound will not detect posterior urethral valves itself, but recognizes the consequences of lower urinary tract obstruction with a dilated thick-walled bladder and dilation of the prostatic portion of the urethra. After birth, urine drainage has to be secured by placement of a bladder catheter, and imaging is needed to confirm the presence of the urethral valves and estimate the degree of damage to the kidney. Consequences of posterior urethral valves depend on the degree of renal dysplasia and bladder dysfunction. Prevention or minimization of such consequences by intrauterine urine drainage has not definitively shown a benefit of early vesico-amniotic shunting.


2019 ◽  
Vol 201 (1) ◽  
pp. 162-168 ◽  
Author(s):  
Patricio C. Gargollo ◽  
Candace Granberg ◽  
Edward Gong ◽  
Duong Tu ◽  
Benjamin Whittam ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Khalil Chalhoub ◽  
Rawad Abou Zahr ◽  
Elias Mansour ◽  
Mona Aoun ◽  
Michel Jabbour

Primary mature retroperitoneal teratomas are rare tumors most commonly occurring in adult females. These tumors are usually asymptomatic since they have no attachments to specific organs. We present a rare case of a 28-year-old male with 2-month history of lower urinary tract symptoms, who was found to have a primary mature cystic teratoma abutting the prostate.


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