Melatonin Does Not Improve Sleep Quality in a Randomized Placebo-controlled Trial After Primary Total Joint Arthroplasty

Objective To compare the efficacy of transcutaneous electrical acupoint stimulation (TEAS) combined with diazepam against diazepam alone for treatment of acute alcohol withdrawal syndrome (AWS). Methods In this double-blind randomized sham-controlled trial, men with acute AWS were randomly allocated to either a group treated with TEAS combined with diazepam (n = 57) or a control group treated with sham TEAS combined with diazepam (n = 60). Treatment was performed at four acupoints twice a day for 14 days. The Clinical Institute Withdrawal Assessment for Alcohol Scale (CIWA-Ar), visual analogue scale (VAS), Pittsburgh Sleep Quality Index (PSQI) and modified Epworth Sleepiness Scale (mESS) were used to evaluate treatment efficacy. Results All scores improved significantly in both groups during the trial. CIWA-Ar scores were lower in the TEAS group than in the control group from day 3 until the end of observation. VAS and mESS scores were also lower in the TEAS group than in the control group on day 7. VAS and PSQI scores were lower in the TEAS group on day 14. Conclusion Combining diazepam with TEAS may result in milder AWS symptoms than diazepam alone, improve sleep quality and reduce sleepiness.

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Efficacy of an m-Health Physical Activity and Sleep Intervention to Improve Sleep Quality in Middle-Aged Adults: The Refresh Study Randomized Controlled Trial

Annals of Behavioral Medicine ◽

10.1093/abm/kaz064 ◽

2020 ◽

Vol 54 (7) ◽

pp. 470-483 ◽

Cited By ~ 3

Author(s):

Anna T Rayward ◽

Beatrice Murawski ◽

Mitch J Duncan ◽

Elizabeth G Holliday ◽

Corneel Vandelanotte ◽

...

Keyword(s):

Physical Activity ◽

Sleep Quality ◽

Controlled Trial ◽

Poor Sleep ◽

Middle Aged ◽

Poor Sleep Quality ◽

Sleep Health ◽

Wait List Control ◽

Improve Sleep Quality ◽

Middle Aged Adults

Abstract Background Poor sleep health is highly prevalent. Physical activity is known to improve sleep quality but not specifically targeted in sleep interventions. Purpose To compare the efficacy of a combined physical activity and sleep intervention with a sleep-only intervention and a wait-list control, for improving sleep quality in middle-aged adults without a diagnosed sleep disorder. Methods Three-arm randomized controlled trial (Physical Activity and Sleep Health (PAS), Sleep Health Only (SO), Wait-list Control (CON) groups; 3-month primary time-point, 6-month follow-up) of 275 (PAS = 110, SO = 110, CON = 55) inactive adults (40–65 years) reporting poor sleep quality. The main intervention component was a smartphone/tablet “app” to aid goal setting and self-monitoring physical activity and/or sleep hygiene behaviors (including stress management), and a pedometer for PAS group. Primary outcome was Pittsburgh Sleep Quality Index (PSQI) global score. Secondary outcomes included several self-reported physical activity measures and PSQI subcomponents. Group differences were examined stepwise, first between pooled intervention (PI = PAS + SO) and CON groups, then between PAS and SO groups. Results Compared with CON, PI groups significantly improved PSQI global and subcomponents scores at 3 and 6 months. There were no differences in sleep quality between PAS and SO groups. The PAS group reported significantly less daily sitting time at 3 months and was significantly more likely to report ≥2 days/week resistance training and meeting physical activity guidelines at 6 months than the SO group. Conclusions PIs had statistically significantly improved sleep quality among middle-aged adults with poor sleep quality without a diagnosed sleep disorder. The adjunctive physical activity intervention did not additionally improve sleep quality. Clinical Trial information Australian New Zealand Clinical Trial Registry: ACTRN12617000680369; Universal Trial number: U1111-1194-2680; Human Research Ethics Committee, Blinded by request of journal: H-2016-0267.

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Acupressure to improve sleep quality of older people in residential aged care: a randomised controlled trial protocol

Trials ◽

10.1186/s13063-020-04286-2 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Nant Thin Thin Hmwe ◽

Graeme Browne ◽

Lyndall Mollart ◽

Viv Allanson ◽

Sally Wai-Chi Chan

Keyword(s):

Randomised Controlled Trial ◽

Sleep Quality ◽

Older People ◽

Controlled Trial ◽

Aged Care ◽

Residential Aged Care ◽

Trial Protocol ◽

Improve Sleep Quality ◽

Randomised Controlled

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The Effect of Psychosensory Therapy on Short-term Outcomes of Total Joint Arthroplasty: A Randomized Controlled Trial

Orthopedics ◽

10.3928/01477447-20181010-04 ◽

2018 ◽

Vol 41 (6) ◽

pp. e848-e853

Author(s):

Zlatan Cizmic ◽

Emmanuel Edusei ◽

Afshin A. Anoushiravani ◽

Joseph Zuckerman ◽

Ronald Ruden ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Total Joint Arthroplasty ◽

Controlled Trial ◽

Joint Arthroplasty ◽

Short Term ◽

Randomized Controlled

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Randomized controlled trial of exercise interventions to improve sleep quality and daytime sleepiness in individuals with multiple sclerosis: A pilot study

Multiple Sclerosis Journal - Experimental Translational and Clinical ◽

10.1177/2055217316680639 ◽

2016 ◽

Vol 2 ◽

pp. 205521731668063 ◽

Cited By ~ 4

Author(s):

Catherine F Siengsukon ◽

Mayis Aldughmi ◽

Melike Kahya ◽

Jared Bruce ◽

Sharon Lynch ◽

...

Keyword(s):

Multiple Sclerosis ◽

Randomized Controlled Trial ◽

Sleep Quality ◽

Daytime Sleepiness ◽

Controlled Trial ◽

Moderate Intensity ◽

Exercise Interventions ◽

Moderate Improvement ◽

Randomized Controlled ◽

Improve Sleep Quality

Background Nearly 70% of individuals with multiple sclerosis (MS) experience sleep disturbances. Increasing physical activity in people with MS has been shown to produce a moderate improvement in sleep quality, and exercise has been shown to improve sleep quality in non-neurologically impaired adults. Objective The purpose of this pilot randomized controlled trial study was to examine the effect of two exercise interventions on sleep quality and daytime sleepiness in individuals with MS. Methods Twenty-eight individuals with relapsing–remitting or secondary progressive MS were randomized into one of two 12-week exercise interventions: a supervised, moderate-intensity aerobic exercise (AE) program or an unsupervised, low-intensity walking and stretching (WS) program. Only individuals who were ≥ 70% compliant with the programs were included in analysis ( n = 12 AE; n = 10 WS). Results Both groups demonstrated a moderate improvement in sleep quality, although only the improvement by the WS group was statistically significant. Only the AE group demonstrated a significant improvement in daytime sleepiness. Change in sleep quality and daytime sleepiness was not correlated with disease severity or with change in cardiovascular fitness, depression, or fatigue. Conclusion The mechanisms for improvement in sleep quality and daytime sleepiness need further investigation, but may be due to introduction of zeitgebers to improve circadian rhythm.

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