HIV Viral Dynamic under Treatment with Intracellular Delay and Virus Decay as Interactive Parameters
2021 ◽
Vol 22
(2)
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pp. 291-306
Keyword(s):
A Cell
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Treatment with antiviral drugs for human immunodeficiency virus type 1 (HIV-1) infection causes a rapid reduction in plasma viral load. Viral decline occurs in several stages and provides information on important kinetic constants of virus replication in vivo and pharmacodynamic properties. We present a mathematical model that not only considers the intracellular phase of the viral life cycle, defined as the time between the infection of a cell and the production of new viral particles, but we also consider that this parameter together with the virus decay are interactive fuzzy numbers.
2005 ◽
Vol 86
(12)
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pp. 3369-3373
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2000 ◽
Vol 74
(15)
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pp. 7039-7047
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Keyword(s):
2003 ◽
Vol 84
(10)
◽
pp. 2715-2722
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2001 ◽
Vol 75
(10)
◽
pp. 4832-4842
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Keyword(s):