scholarly journals Statin Therapy in HIGH-Risk Individuals with NORMal Coronary Arteries: The HIGH-NORM Study

2021 ◽  
Author(s):  
Kyeong-Hyeon Chun ◽  
Jung Mi Park ◽  
Chan Joo Lee ◽  
Jaewon Oh ◽  
Sungha Park ◽  
...  
Keyword(s):  
High Risk ◽  
Statin Therapy ◽  
Coronary Arteries ◽  
Normal Coronary Arteries

scholarly journals Predicting Locations of High-Risk Plaques in Coronary Arteries in Patients Receiving Statin Therapy

2018 ◽  
Vol 37 (1) ◽  
pp. 151-161 ◽  
Author(s):  
Ling Zhang ◽  
Andreas Wahle ◽  
Zhi Chen ◽  
John J. Lopez ◽  
Tomas Kovarnik ◽  
...  
Keyword(s):  
High Risk ◽  
Statin Therapy ◽  
Coronary Arteries

Coronary artery embolism in a patient with mechanical heart valve and normal coronary arteries (clinical case)

2019 ◽  
Vol 17 (2) ◽  
pp. 153-157
Author(s):  
A. Z. Sharafeev ◽  
◽  
A. F. Khalirakhmanov ◽  
A. I. Alkhazurov ◽  
E. A. Gaziev ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Heart Valve ◽  
Coronary Arteries ◽  
Clinical Case ◽  
Mechanical Heart Valve ◽  
Normal Coronary Arteries ◽  
Artery Embolism ◽  
Coronary Artery Embolism

Angina Pectoris in Patients With Aortic Stenosis and Normal Coronary Arteries

Circulation ◽  
1997 ◽  
Vol 95 (4) ◽  
pp. 892-898 ◽  
Author(s):  
Barbara K. Julius ◽  
Martin Spillmann ◽  
Giuseppe Vassalli ◽  
Bruno Villari ◽  
Franz R. Eberli ◽  
...  
Keyword(s):  
Angina Pectoris ◽  
Aortic Stenosis ◽  
Coronary Arteries ◽  
Normal Coronary Arteries

scholarly journals P6454Myocardial infarction with normal coronary arteries (MINCA): risk factors and 1-year prognosis

2017 ◽  
Vol 38 (suppl_1) ◽  
Author(s):  
P.M. Azevedo ◽  
J. Guedes ◽  
J. Bispo ◽  
D. Bento ◽  
D. Carvalho ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Arteries ◽  
Normal Coronary Arteries

scholarly journals Increased Circulating Malondialdehyde-Modified Low-Density Lipoprotein Level Is Associated with High-Risk Plaque in Coronary Computed Tomography Angiography in Patients Receiving Statin Therapy

2021 ◽  
Vol 10 (7) ◽  
pp. 1480
Author(s):  
Keishi Ichikawa ◽  
Toru Miyoshi ◽  
Kazuhiro Osawa ◽  
Takashi Miki ◽  
Hiroshi Ito
Keyword(s):  
Computed Tomography ◽  
High Risk ◽  
Statin Therapy ◽  
Computed Tomography Angiography ◽  
Coronary Computed Tomography Angiography ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Coronary Cta ◽  
Coronary Computed Tomography

Objective: To evaluate the association of serum malondialdehyde low-density lipoprotein (MDA-LDL), an oxidatively modified LDL, with the prevalence of high-risk plaques (HRP) determined with coronary computed tomography angiography (CTA) in statin-treated patients. Methods: This study was a single-center retrospective cohort comprising 268 patients (mean age 67 years, 58% men) with statin therapy and who underwent coronary CTA for suspected stable coronary artery disease. Patients were classified into two groups according to median MDA-LDL level or median LDL-C level. Coronary CTA-verified HRP was defined when two or more characteristics, including positive remodeling, low-density plaques, and spotty calcification, were present. Results: Patients with HRP had higher MDA-LDL (p = 0.011), but not LDL-C (p = 0.867) than those without HRP. High MDA-LDL was independently associated with HRP (odds ratio 1.883, 95% confidential interval 1.082–3.279) after adjustment for traditional risk factors. Regarding incremental value of MDA-LDL for predicting CTA-verified HRP, addition of serum MDA-LDL levels to the baseline model significantly increased global chi-square score from 26.1 to 32.8 (p = 0.010). Conclusions: A high serum MDA-LDL level is an independent predictor of CTA-verified HRP, which can lead to cardiovascular events in statin-treated patients.

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