scholarly journals Correlations Between Venous Acid - Base Status and Renal Function i n Neonatal C alves With Acute Diarrhea

2013 ◽  
Vol 6 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Durmuş Fatih BAŞER ◽  
Turan CİVELEK
Keyword(s):  
Renal Function ◽  
Acute Diarrhea ◽  
Acid Base ◽  
Acid Base Status

scholarly journals Metabolic and volume status evaluation of hemodialysis patients with and without residual renal function in the long interdialytic interval

2019 ◽  
Vol 41 (4) ◽  
pp. 481-491 ◽  
Author(s):  
Lenina Ludimila Sampaio de Almeida ◽  
Luís Henrique Bezerra Cavalanti Sette ◽  
Fernando Luiz Affonso Fonseca ◽  
Leila Silveira Vieira da Silva Bezerra ◽  
Francisco Hélio Oliveira Júnior ◽  
...  
Keyword(s):  
Renal Function ◽  
Serum Potassium ◽  
Ph Value ◽  
Residual Renal Function ◽  
Acid Base ◽  
Serum Samples ◽  
Cross Sectional ◽  
Interdialytic Weight Gain ◽  
Base Disorder ◽  
Acid Base Status

Abstract Introduction: It is unclear whether residual renal function (RRF) in dialysis patients can attenuate the metabolic impact of the long 68-hour interdialytic interval, in which water, acid, and electrolyte accumulation occurs. Objective: to evaluate serum electrolyte levels, water balance, and acid-base status in dialytic patients with and without RRF over the long interdialytic interval (LII). Methodology: this was a single-center, cross-sectional, and analytical study that compared patients with and without RRF, defined by diuresis above 200 mL in 24 hours. Patients were weighed and serum samples were collected for biochemical and gasometric analysis at the beginning and at the end of the LII. Results: 27 and 24 patients with and without RRF were evaluated, respectively. Patients without RRF had a higher increase in serum potassium during the LII (2.67 x 1.14 mEq/L, p < 0.001), reaching higher values at the end of the study (6.8 x 5.72 mEq/L, p < 0.001) and lower pH value at the beginning of the interval (7.40 x 7.43, p = 0.018). More patients with serum bicarbonate < 18 mEq/L (50 x 14.8%, p = 0.007) and mixed acid-base disorder (57.7 x 29.2%, p = 0.042), as well as greater interdialytic weight gain (14.67 x 8.87 mL/kg/h, p < 0.001) and lower natremia (137 x 139 mEq/L, p = 0.02) at the end of the interval. Calcemia and phosphatemia were not different between the groups. Conclusion: Patients with RRF had better control of serum potassium, sodium, acid-base status, and volemia throughout the LII.

Influence of Renal Function and Diet on Acid-Base Status in Chronic Kidney Disease Patients

2009 ◽  
Vol 19 (2) ◽  
pp. 178-182 ◽  
Author(s):  
Viviane O. Leal ◽  
Alvimar G. Delgado ◽  
Maurilo Leite ◽  
William E. Mitch ◽  
Denise Mafra
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Acid Base ◽  
Acid Base Status

scholarly journals Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex

2017 ◽  
Vol 42 (12) ◽  
pp. 1330-1340 ◽  
Author(s):  
Enni-Maria Hietavala ◽  
Jeffrey R. Stout ◽  
Lynda A. Frassetto ◽  
Risto Puurtinen ◽  
Hannu Pitkänen ◽  
...  
Keyword(s):  
Renal Function ◽  
Oxygen Uptake ◽  
Exercise Performance ◽  
Maximal Oxygen Uptake ◽  
The Body ◽  
Acid Base ◽  
Dietary Acid Load ◽  
Dietary Acid ◽  
Acid Load ◽  
Acid Base Status

Diet composition influences acid-base status of the body. This may become more relevant as renal functional capacity declines with aging. We examined the effects of low (LD) versus high dietary acid load (HD) on blood acid-base status and exercise performance. Participants included 22 adolescents, 33 young adults (YA), and 33 elderly (EL), who followed a 7-day LD and HD in a randomized order. At the end of both diet periods the subjects performed a cycle ergometer test (3 × 10 min at 35%, 55%, 75%, and (except EL) until exhaustion at 100% of maximal oxygen uptake). At the beginning of and after the diet periods, blood samples were collected at rest and after all workloads. Oxygen uptake, respiratory exchange ratio (RER), and heart rate (HR) were monitored during cycling. In YA and EL, bicarbonate (HCO3−) and base excess (BE) decreased over the HD period, and HCO3−, BE, and pH were lower at rest after HD compared with LD. In YA and EL women, HCO3− and BE were lower at submaximal workloads after HD compared with LD. In YA women, the maximal workload was 19% shorter and maximal oxygen uptake, RER, and HR were lower after HD compared with LD. Our data uniquely suggests that better renal function is associated with higher availability of bases, which may diminish exercise-induced acidosis and improve maximal aerobic performance. Differences in glomerular filtration rate between the subject groups likely explains the larger effects of dietary acid load in the elderly compared with younger subjects and in women compared with men.

scholarly journals RENAL RISCS IN DETERMINATION OF BRONCHIAL ASTHMA PHENOTYPES

2015 ◽  
pp. 26-29
Author(s):  
Zh.D. Semydotska ◽  
I.A. Cherniacova ◽  
G.V. Eremenko
Keyword(s):  
Renal Function ◽  
Metabolic Acidosis ◽  
Bronchial Asthma ◽  
Respiratory Alkalosis ◽  
Bronchial Obstruction ◽  
Acid Base Balance ◽  
Acid Base ◽  
Asthma Phenotypes ◽  
Base Balance ◽  
Acid Base Status

The aim of this investigation was to study acid - secretory renal function and acid - base balance in patients with bronchial asthma in order to optimize the diagnostics and treatment from the pposition of phenotyping. Materials and methods. In 102 patients with moderate bronchial asthma there was studied the excretion of titratable acids by titration method, excretion ofammonium by Van Slyk - Palmer’s method and acid - base status of the organism in the venous blood by blood gas analyzer 348. Respiratory function was studied on computer spirograph «Microlab 330». Results. Studied patients were divided into 3 groups according to the disorders of acid - base balance and acidsecretory renal function: 62 patients had respiratory acidosis and a significant increase in the excretion of titratable acid and ammonium; in 28 patients metabolic acidosis and a moderate increase in acid - secretory renal function were ascertained; in 12 patients respiratory alkalosis was found, acid - secretory renal function did not differ significantly from that of healthy persons. The most pronounced bronchial obstruction and bronchial hyperreactivity were observed in patients with respiratory alkalosis. The intravenous infusion of buffered 4.2% solution of sodium hydrocarbonate was included in complex therapy in 14patients with metabolic acidosis. After this treatment marked improvement of bronchial obstruction was established, as well as normalization of BE, pCO,, pO,, increased blood pH, improve control over asthma. The possibility to separate asthma phenotypes (subphenotypes) according to the disorders of the acid - base balance and acid - secretory renal function is discussed. Conclusions. Monitoring of acid - base status and acid - secretory renal function can be used in patients with asthma to separate phenotypes (subphenotypes) for disease diagnostics and treatment optimization.

scholarly journals Kidney Function and Net Glucose Production in Normal and Acidotic Sheep

1973 ◽  
Vol 26 (6) ◽  
pp. 1389 ◽  
Author(s):  
GH Mcintosh ◽  
O H Filsell ◽  
IG Jarrett
Keyword(s):  
Blood Flow ◽  
Renal Function ◽  
Body Weight ◽  
Glucose Concentration ◽  
Physiological Response ◽  
Filtration Rate ◽  
Glucose Production ◽  
Acid Base ◽  
Major Site ◽  
Acid Base Status

Net glucose production and renal function were assessed simultaneously in normal sheep which were subsequently made acidotic by ammonium chloride administration. Arteriovenous differences in glucose concentration were measured, together with p-aminohippuric acid and inulin clearances in one kidney. In normal sheep there was a small net output of glucose by the kidney [20 Ilg min- 1 (kg body weight)-l] which was increased threefold during acidosis. The increase was associated with an elevated venous-arterial difference in glucose concentration and a fall in renal blood flow, while glomerular filtration rate did not change. The increase in the proportion of blood being filtered indicates that there is a greater perfusion of the active zone of the cortex, which is the major site of glucose production in the kidney. This suggests that changed intrarenal events are associated with the physiological response of the kidney to altered acid-base status. The contribution by the kidneys to the overall glucose requirements in sheep, even during acidosis, is unlikely to be greater than 6%.

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