Oxidative stress and serum paraoxonase activity in patients on maintenance hemodialysis

10.5580/8cf ◽  
2010 ◽  
Vol 6 (1) ◽  
Keyword(s):  
Oxidative Stress ◽  
Maintenance Hemodialysis ◽  
Paraoxonase Activity ◽  
Serum Paraoxonase

Vanadyl sulfate treatment improves oxidative stress and increases serum paraoxonase activity in streptozotocin-induced diabetic rats

2006 ◽  
Vol 26 (12) ◽  
pp. 670-676 ◽  
Author(s):  
Sibel Tas ◽  
Emre Sarandol ◽  
Sedef Ziyanok-Ayvalik ◽  
Nihal Ocak ◽  
Zehra Serdar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Rats ◽  
Vanadyl Sulfate ◽  
Paraoxonase Activity ◽  
Serum Paraoxonase

Serum paraoxonase activity and oxidative stress levels in patients with cutaneous anthrax

2016 ◽  
Vol 36 (7) ◽  
pp. 663-669
Author(s):  
S Karadas ◽  
M Aslan ◽  
MR Ceylan ◽  
M Sunnetcioglu ◽  
N Bozan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Paraoxonase 1 ◽  
Pon1 Activity ◽  
Bacterial Disease ◽  
Healthy Controls ◽  
Paraoxonase Activity ◽  
Cutaneous Anthrax ◽  
Bacterium Bacillus ◽  
Serum Paraoxonase ◽  
And Oxidative Stress

Introduction: Anthrax is a bacterial disease caused by the aerobic sporeforming bacterium Bacillus anthracis. It has been suggested that oxidative stress plays an important role in the pathogenesis of B. anthracis. The aim of this study was to investigate serum paraoxonase 1 (PON1) activity, catalase activity, malondialdehyde (MDA) levels, and superoxide dismutase (SOD) levels in patients with cutaneous anthrax. Materials and methods: Fifteen patients with cutaneous anthrax and 15 healthy controls were enrolled in this study. The serum MDA levels, SOD levels, paraoxonase, arylesterase, and catalase activities were measured using a spectrophotometer. Results: The serum SOD levels, paraoxonase, arylesterase, and catalase activities were significantly lower in patients with cutaneous anthrax than in controls (for all, p < 0.001), whereas MDA levels were significantly higher ( p < 0.001). No significant correlation was found between serum paraoxonase activity, arylesterase activity, SOD levels, and MDA levels (all, p > 0.05) in patients with cutaneous anthrax. Conclusions: The current study was the first to show decreased antioxidant levels and increased oxidant levels in patients with cutaneous anthrax. Therefore, decreased PON1 activity may play a role in the pathogenesis of cutaneous anthrax.

Oxidative stress and serum paraoxonase activity in experimental hypothyroidism: effect of vitamin E supplementation

2004 ◽  
Vol 23 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Emre Sarandöl ◽  
Sibel Taş ◽  
Melahat Dirican ◽  
Zehra Serdar
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Paraoxonase Activity ◽  
Serum Paraoxonase ◽  
Vitamin E Supplementation

Serum paraoxonase activity and oxidative stress in patients with adult nephrotic syndrome

2011 ◽  
Vol 218 (1) ◽  
pp. 243-246 ◽  
Author(s):  
Yasemin Usul Soyoral ◽  
Mehmet Aslan ◽  
Habib Emre ◽  
Huseyin Begenik ◽  
Fatih Mehmet Erdur ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nephrotic Syndrome ◽  
Paraoxonase Activity ◽  
Serum Paraoxonase ◽  
And Oxidative Stress

Association between serum paraoxonase activity and oxidative stress in acute coronary syndromes

2004 ◽  
Vol 59 (6) ◽  
pp. 606-611 ◽  
Author(s):  
Ceyda KABAROGLU ◽  
Isil MUTAF ◽  
Bahar BOYDAK ◽  
Dilek ÖZMEN ◽  
Sara HABIF ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Acute Coronary Syndromes ◽  
Paraoxonase Activity ◽  
Coronary Syndromes ◽  
Serum Paraoxonase ◽  
And Oxidative Stress

Association of serum paraoxonase activity with insulin sensitivity and oxidative stress in hyperthyroid and TSH-suppressed nodular goitre patients

2004 ◽  
Vol 61 (4) ◽  
pp. 515-521 ◽  
Author(s):  
Dilek Gogas Yavuz ◽  
Meral Yuksel ◽  
Oguzhan Deyneli ◽  
Yesim Ozen ◽  
Hasan Aydin ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Sensitivity ◽  
Nodular Goitre ◽  
Paraoxonase Activity ◽  
Serum Paraoxonase ◽  
And Oxidative Stress

scholarly journals Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2323
Author(s):  
Kazuhiko Kotani ◽  
Jun Watanabe ◽  
Kouichi Miura ◽  
Alejandro Gugliucci
Keyword(s):  
Oxidative Stress ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Meta Analysis ◽  
Laboratory Data ◽  
Paraoxonase 1 ◽  
Mixed Data ◽  
Alcoholic Fatty Liver ◽  
Paraoxonase Activity

Oxidative stress is involved in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). However, reliable biomarkers of NAFLD in relation to oxidative stress are not available. While paraoxonase 1 (PON1) is an antioxidant biomarker, there appears to be mixed data on PON-1 in patients with NAFLD. The aim of this meta-analysis was to assess the current data on PON1 activity (i.e., paraoxonase and arylesterase) in patients with NAFLD. A PubMed, CENTRAL, and Embase search identified 12 eligible articles. In the meta-analysis, the paraoxonase activity was low in patients with NAFLD (mean difference (MD) −27.17 U/L; 95% confidence interval (CI) −37.31 to −17.03). No difference was noted in the arylesterase activity (MD 2.45 U/L; 95% CI −39.83 to 44.74). In a subgroup analysis, the paraoxonase activity was low in biopsy-proven nonalcoholic steatohepatitis (MD −92.11 U/L; 95% CI −115.11 to −69.11), while the activity in NAFLD as diagnosed by ultrasonography or laboratory data was similar (MD −2.91 U/L; 95% CI −11.63 to 5.80) to that of non-NAFLD. In summary, the PON1, especially paraoxonase, activity could be a useful biomarker of NAFLD. Further studies are warranted to ascertain the relevance of PON1 measurements in patients with NAFLD.

scholarly journals Methylmercury exposure, PON1 gene variants and serum paraoxonase activity in Eastern James Bay Cree adults

2014 ◽  
Vol 24 (6) ◽  
pp. 608-614 ◽  
Author(s):  
Olivia Drescher ◽  
Eric Dewailly ◽  
Caroline Diorio ◽  
Nathalie Ouellet ◽  
Elhadji Anassour Laouan Sidi ◽  
...  
Keyword(s):  
Gene Variants ◽  
James Bay ◽  
Paraoxonase Activity ◽  
Pon1 Gene ◽  
James Bay Cree ◽  
Methylmercury Exposure ◽  
Serum Paraoxonase
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