scholarly journals Thrombolytic effect of streptokinase infusion assessed by ST-segment resolution between diabetic and non-diabetic myocardial infarction patients

2012 ◽  
Vol 19 (2) ◽  
pp. 168-173 ◽  
Author(s):  
Mohammad Masoomi ◽  
Sadra Samadi ◽  
Mehrdad Sheikhvatan
2021 ◽  
Vol 7 (5) ◽  
pp. 1435-1442
Author(s):  
Yang Yang ◽  
Xiuyu Liang ◽  
Yuzhe Fan ◽  
Gendong Zhou ◽  
Xiaohong Zhang

To explore the relationship between the changes of ECG indexes and the prognosis after PCI in patients with acute ST-elevation myocardial infarction (STEMI), and to develop the evaluation method and analyze the advantages and characteristics. 420 patients with acute myocardial infarction (AMI) were admitted to our hospital from March 2017 to April 2020. They were divided into the observation group (ST segment elevation type) with 220 patients and control group (non-ST segment elevation type) with 200 patients according to whether ST segment elevation was or not. ECG was detected before and 1 hour after operation, evaluation of thrombolytic effect, 6-minute walking test and echocardiography were performed 3 months after operation. Compared with the control group, the ECG of the observation group showed St Compared with the control group, the thrombolytic effect of the observation group was significantly improved, and the difference was statistically significant (P < 0.05); compared with the control group, the thrombolysis effect of the observation group was significantly improved, the difference was statistically significant (P < 0.05); ECG index can effectively reflect the recovery of cardiac function after PCI in patients with acute STEMI, and can effectively indicate the improvement of symptoms in patients with AMI, which is worthy of clinical application.


2013 ◽  
Vol 24 (1) ◽  
pp. 16-19
Author(s):  
Md Faruque Uddin ◽  
AK Fazlul Hoque

A prospective interventional study was carried out to compare  the thrombolytic effect of streptokinase between diabetic and  non-diabetic myocardial infarction patients. Out of 187 study  subjects with acute ST segment elevation myocardial  infarction (STEMI), admitted at coronary care unit, 126  patients were non-diabetic and 61 patients were diabetic.  Streptokinase was administered to all patients. Resolution  (reduction) of elevated ST segment was evaluated after 90 min  of streptokinase administration. Successful reperfusion  (=70% ST-resolution) was significantly higher in  non-diabetic than diabetic (p<0.001), while failed reperfusion  (<30% ST resolution) was significantly higher in diabetic  patients (p<0.001). It may be concluded that diabetes mellitus  might affect the thrombolytic outcome of acute myocardial  infarction patients with diabetes mellitus. DOI: http://dx.doi.org/10.3329/medtoday.v24i1.14108 Medicine TODAY Vol.24(1) 2012 pp.16-19


Sign in / Sign up

Export Citation Format

Share Document