Protective effects of anti-oxidant supplementations on contrast-induced nephropathy after coronary angiography: an updated and comprehensive meta-analysis and systematic review

2016 ◽  
pp. 610-626 ◽  
Author(s):  
Sadeq Ali-Hasan-Al-Saegh ◽  
Seyed Jalil Mirhosseini ◽  
Zahra Ghodratipour ◽  
Zahra Sarafan-Chaharsoughi ◽  
Ali Mohammad Dehghan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Angiography ◽  
Meta Analysis ◽  
Protective Effects ◽  
Contrast Induced Nephropathy ◽  
Anti Oxidant

Strategies Preventing Contrast-Induced Nephropathy After Coronary Angiography: A Comprehensive Meta-Analysis and Systematic Review of 125 Randomized Controlled Trials

Angiology ◽  
2016 ◽  
Vol 68 (5) ◽  
pp. 389-413 ◽  
Author(s):  
Sadegh Ali-Hassan-Sayegh ◽  
Seyed Jalil Mirhosseini ◽  
Zahra Ghodratipour ◽  
Zahra Sarrafan-Chaharsoughi ◽  
Elham Rahimizadeh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Angiography ◽  
Vitamin C ◽  
Enzyme Inhibitors ◽  
Meta Analysis ◽  
Angiotensin Converting Enzyme Inhibitors ◽  
Pooled Analysis ◽  
Loop Diuretics ◽  
Contrast Induced Nephropathy ◽  
Converting Enzyme Inhibitors

This systematic review with meta-analysis sought to determine the strength of evidence for the effects of hydration (sodium bicarbonate [SB] and normal saline [NS]), supplementations ( N-acetylcysteine [NAC] and vitamin C), and some common drugs (adenosine antagonists [AAs], statins, loop diuretics, and angiotensin-converting enzyme inhibitors [ACEIs]) on the incidence of contrast-induced nephropathy (CIN) and requirement for hemodialysis after coronary angiography. After screening, a total of 125 trials that reported outcomes were identified. Pooled analysis indicated beneficial effects of SB versus NS (odds ratio [OR] = 0.73; 95% confidence interval [CI]: 0.56-0.94; P = .01), NAC (OR = 0.79; 95% CI: 0.70-0.88; P = .001), vitamin C (OR = 0.64; 95% CI: 0.45-0.89; P = .01), statins (OR = 0.45; 95% CI: 0.35-0.57; P = .001), AA (OR = 0.28; 95% CI: 0.14-0.47; P = .001), loop diuretics (OR = 0.97; 95% CI: 0.33-2.85; P = .9), and ACEI (OR = 1.06; 95% CI: 0.69-1.61; P = .8). Overall, hydration with SB, use of supplements, such as NAC and vitamin C, and administration of statins and AA should always be considered for the prevention of CIN after coronary angiography.

Pre-Procedural Hyperglycemia Increases the Risk of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 21 (11) ◽  
pp. 1377-1385 ◽  
Author(s):  
Jakrin Kewcharoen ◽  
Ruiyang Yi ◽  
Angkawipa Trongtorsak ◽  
Narut Prasitlumkum ◽  
Poemlarp Mekraksakit ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Angiography ◽  
Meta Analysis ◽  
Contrast Induced Nephropathy

Predictive Value of Hepatorenal Status in Contrast-Induced Nephropathy Among Patients Receiving Coronary Angiography and/or Intervention: A Systematic Review and Meta-Analysis

Angiology ◽  
2018 ◽  
Vol 70 (7) ◽  
pp. 633-641 ◽  
Author(s):  
Enyuan Zhang ◽  
Yaru Lu ◽  
Gang Chen ◽  
Lingyu Huang ◽  
Jingkun Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Renal Function ◽  
Coronary Angiography ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Clinical Situation ◽  
Pooled Analysis ◽  
Contrast Induced Nephropathy ◽  
Low Serum

Background: Low serum albumin, high blood urea nitrogen (BUN), and uric acid are regarded closely related to the incidence of contrast-induced nephropathy (CIN), whereas it remains unclear whether they can function as predictors of CIN onset. The objective of this systematic review and meta-analysis was to explore the association between abovementioned indicators and CIN incidence rate in patients receiving coronary angiography (CAG) and/or intervention. Methods: Clinical studies were retrieved from the electronic databases of PubMed, EMBASE, Google Scholar, Clinical Trials, and ScienceDirect from their inception to July 13, 2018. Meta-analysis was performed on pooled eligible studies to determine whether these hepatorenal indicators were associated with CIN. Results: A total of 18 studies involving 16 171 patients were included in the meta-analysis. Pooled analysis results revealed that patients with hypoalbuminemia (odds ratio [OR] = 3.09, 95% confidence interval [CI] = 1.44-6.64, P = .004) and hyperuricemia (OR = 1.32, 95% CI = 1.15-1.50, P < .0001) both exhibited significantly higher CIN rates, regardless of the study design, renal function, and whether urgent clinical situation or not. However, there was no significant association between serum BUN and CIN risk. Conclusion: Hypoalbuminemia and hyperuricemia are independently associated with the occurrence of CIN among the patients undergoing CAG and/or intervention.

Sign in / Sign up

Export Citation Format

Share Document