scholarly journals Iodine isotope (131I) therapy for toxic nodular goitre: treatment efficacy parameters

2012 ◽  
Vol 15 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Piotr Szumowski ◽  
Franciszek Rogowski ◽  
Saeid Abdelrazek ◽  
Agnieszka Kociura-Sawicka ◽  
Anna Sokolik-Ostasz
Keyword(s):  
Treatment Efficacy ◽  
131I Therapy ◽  
Nodular Goitre ◽  
Iodine Isotope ◽  
Efficacy Parameters ◽  
Toxic Nodular Goitre

scholarly journals The influence of non-radioactive iodine (127I) on the outcome of radioiodine (131I) therapy in patients with Graves’ disease and toxic nodular goitre

2011 ◽  
Vol 14 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Franciszek Rogowski ◽  
Saeid Abdelrazek ◽  
Piotr Szumowski ◽  
Anna Zonenberg ◽  
Adam Parfienczyk ◽  
...  
Keyword(s):  
Radioactive Iodine ◽  
131I Therapy ◽  
Graves Disease ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre

The efficacy of radioiodine therapy in patients with non-toxic nodular goitre with large cold nodule

2015 ◽  
Author(s):  
Saeid Abdelrazek ◽  
Piotr Szumowski ◽  
Katrzyna Siewko ◽  
Janusz Mysliwiec ◽  
Malgorzata Szelachowska ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre ◽  
Cold Nodule

Enzyme-linked immunosorbent assay of autoantibodies reacting with thyroid plasma membrane antigens in sera of patients with autoimmune thyroid diseases

1986 ◽  
Vol 113 (2) ◽  
pp. 255-260 ◽  
Author(s):  
Andrzej Gardas ◽  
Kathleen L. Rives
Keyword(s):  
Plasma Membrane ◽  
Immunosorbent Assay ◽  
Lupus Erythematosus ◽  
Antithyroid Drug ◽  
Cross Reactivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Autoimmune Thyroid Diseases ◽  
Nodular Goitre ◽  
Membrane Antigens ◽  
Toxic Nodular Goitre

Abstract. A sensitive and specific enzyme-linked immunosorbent assay (ELISA) for the detection of autoantibodies reacting with thyroid plasma membrane antigens has been established. Autoantibodies reacting with thyroid plasma membrane antigens were detected by the ELISA in 95% of untreated hyperthyroid Graves', 68% of antithyroid drug-treated Graves' up to four months of the therapy, in 62% of Hashimoto's thyroiditis and in 8.9% of toxic nodular goitre. The ELISA was negative in 100% healthy blood donors, 100% non-toxic nodular goitre, in 12 patients with rheumatoid arthritis, 18 patients with scleroderma and 94% of patients with systemic lupus erythematosus. The mean value of autoantibodies titre was higher in untreated hyperthyroid Graves' (1:84 000) and lowest in positive patients with autoimmune disease of non-thyroid origin (1:4000). The cross-reactivity of antimicrosomal antigen antibodies was below 10%; there was no influence of antithyroglobulin antibodies on the ELISA; and most of the autoantibodies react with plasma membrane antigens different from the TSH binding sites.

Development of hypothyroidism during long-term follow-up of patients with toxic nodular goitre after radioiodine therapy

2012 ◽  
Vol 76 (2) ◽  
pp. 297-303 ◽  
Author(s):  
Deniz Kahraman ◽  
Christian Keller ◽  
Christina Schneider ◽  
Wolfgang Eschner ◽  
Ferdinand Sudbrock ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Long Term Follow Up ◽  
Toxic Nodular Goitre

Toxic nodular goitre in the cat

1982 ◽  
Vol 23 (1) ◽  
pp. 1-12 ◽  
Author(s):  
MARGARETHE HOENIG ◽  
MICHAEL H. GOLDSCHMIDT ◽  
DUNCAN C. FERGUSON ◽  
KAARON KOCH ◽  
MICHAEL J. EYMONTT
Keyword(s):  
Nodular Goitre ◽  
Toxic Nodular Goitre

Is Paranodular, Grossly Normal Thyroid Tissue from Patients with Non-Toxic Nodular Goitre Really Normal?

1984 ◽  
Vol 16 (09) ◽  
pp. 504-505
Author(s):  
M. Solter ◽  
D. Tišlarić ◽  
M. Dominis ◽  
M. Sekso ◽  
B. Pegan ◽  
...  
Keyword(s):  
Thyroid Tissue ◽  
Normal Thyroid Tissue ◽  
Nodular Goitre ◽  
Normal Thyroid ◽  
Toxic Nodular Goitre

Thyroid Function after Medical and Surgical Treatment of Thyrotoxicosis and Non-Toxic Nodular Goitre

1975 ◽  
Vol 48 (1) ◽  
pp. 3P-4P
Author(s):  
N. W. Oakley ◽  
R. D. Simpson ◽  
F. M. Brooke ◽  
D. Burnett ◽  
T. F. Woods ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Thyroid Function ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre

IODIDE-PEROXIDASE ACTIVITY IN HUMAN THYROID. I. STUDIES ON NON-TOXIC NODULAR GOITRE

1969 ◽  
Vol 62 (2) ◽  
pp. 193-198 ◽  
Author(s):  
H. Niepomniszcze ◽  
N. Altschuler ◽  
M. H. Korob ◽  
O. J. Degrossi
Keyword(s):  
Enzymatic Activity ◽  
Peroxidase Activity ◽  
Histological Diagnosis ◽  
Human Thyroid ◽  
Enzymatic System ◽  
Iodide Uptake ◽  
Nodular Goitre ◽  
Nodular Tissue ◽  
Toxic Nodular Goitre

ABSTRACT Eighteen nodules from thirteen patients with non-toxic nodular goitre were studied. The nodules were classified, according to the 131I scintiscanner, into »cold« and »warm« types. The histological diagnosis of all the glands was multinodular colloid goitre. An enzymatic system with iodide-peroxidase activity was prepared from nodular tissue obtained by surgical thyroidectomy. The enzymatic activity was determined by spectrophotometry at 287.5 nm by measuring the formation of triiodide ion. The group of »cold« nodules showed an average of 333 units of enzymatic activity and the »warm« nodules 940 units. The significance of the correlation between the capacity for iodide-uptake, the iodide-peroxidase activity and the involution of the metabolic steps in the nodular goitre is discussed.

STATISTICAL EVALUATION OF SYMPTOMS AND CLINICAL SIGNS IN THE DIAGNOSIS OF HYPERTHYROIDISM

1969 ◽  
Vol 62 (4_Suppla) ◽  
pp. S37-S42
Author(s):  
B.-A. Lamberg ◽  
O. P. Heinonen ◽  
A. Aro ◽  
M. Viherkoski ◽  
P. Knekt
Keyword(s):  
Nervous System ◽  
Statistical Evaluation ◽  
Clinical Signs ◽  
Control Group ◽  
Nodular Goitre ◽  
The Difference ◽  
Hyperthyroid Patients ◽  
Symptoms And Signs ◽  
Toxic Nodular Goitre ◽  
Stimulation Of

ABSTRACT The occurrence of 15 symptoms and 11 clinical signs was studied in 101 hyperthyroid patients and 106 euthyroid subjects. The hyperthyroid group comprised 50 patients with toxic diffuse goitre and 51 with toxic nodular goitre. The control group included 31 subjects with non-toxic goitre. The symptoms and signs were registered in a standardised manner. The difference in the frequency of each symptom and sign between the hyperthyroid and the control group was analysed statistically. The most discriminatory were the symptoms and signs related to excessive production of heat and to stimulation of the nervous system. The results were mostly in agreement with those of the few previously existing reports. Lid signs, however, were in both groups less frequent than in a British material. The need for standardisation in registration of symptoms and signs is emphasized.

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