scholarly journals Increase in the incidence of parotid gland tumors in the years 2005–2014

2017 ◽  
Vol 71 (2) ◽  
pp. 29-34 ◽  
Author(s):  
Grażyna Stryjewska-Makuch ◽  
Bogdan Kolebacz ◽  
Małgorzata A. Janik ◽  
Agnieszka Wolnik

Introduction: Salivary gland tumours account for 3-6% of tumours of the head and neck. About 80% of salivary gland tumors occur in parotid glands, 10-17% of which are malignant The aim of the study was to assess whether there is an upward trend in cancer incidence within the parotid glands, with particular emphasis on cancers. Materials and methods: 322 patients underwent surgery and 328 parotid gland tumours were removed in the years 2005-2014 at the Department of Laryngology and Laryngological Oncology of the Upper Silesian Medical Centre in Katowice-Ochojec. Clinical, histopathological and statistical analyses of the removed parotid gland tumours were performed. Results and discussion: A significant increase in the incidence of benign tumours, especially mixed and Warthin tumours, was demonstrated. There was no significant increase in the number of malignant tumours over the analysed period of time.

1987 ◽  
Vol 101 (11) ◽  
pp. 1175-1181 ◽  
Author(s):  
Jae Y. Ro ◽  
Bruce Mackay ◽  
John G. Batsakis ◽  
Joiner Cartwright

AbstractThe ultrastructural, X-ray microanalytical, histochemical and immunocytochemi-cal features of intraluminal crystalloids found in adenocarcinomas of the parotid gland have been studied. The crystalloids, putatively derived from an abnormal crystalization of salivary duct proteins, are considerably different from the crystalloids found in normal parotid glands, pleomorphic adenomas, and sialocysts.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Victor Shing Howe To ◽  
Jimmy Yu Wai Chan ◽  
Raymond K. Y. Tsang ◽  
William I. Wei

Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a means of coming to a definitive diagnosis. Benign tumours and early low-grade malignancies can be adequately treated with surgery alone, while more advanced and high-grade tumours with regional lymph node metastasis will require postoperative radiotherapy. The role of chemotherapy remains largely palliative. This paper highlights some of the more important aspects in the management of salivary gland tumours.


Author(s):  
M. Zulfath Nihara ◽  
K. Udhaya Chandrika ◽  
R. Vijaya Sundari ◽  
Tan Shi Yi ◽  
Maya Ramesh

Salivary gland pathology is diverse in nature and mainly inflammatory or neoplastic. Salivary gland tumours present as painless enlarging masses. Most of the tumours are located in parotid glands and many of them are benign. The management of these tumours is difficult just like the diagnosis of benign and malignant tumours. Fine Needle Aspiration Cytology (FNAC) and Magnetic Resonance Imaging (MRI) scans provide some useful information in diagnosis, but most of the tumours will require surgical excision as a means of coming to a definitive diagnosis. Surgical approach is adequate for benign tumours and early low grade malignancies whereas post operative radiotherapy is needed for more advanced and high grade tumours with regional lymph node metastasis. The role of chemotherapy remains largely palliative. This article throws light on some of the more important aspects in the investigations of salivary gland pathologies.


2017 ◽  
Vol 24 (09) ◽  
pp. 1327-1330
Author(s):  
Arifullah - ◽  
Irfan Ul Islam Nasir ◽  
Syed Zafar Hassan ◽  
Ghulam Muhammad

Objectives: The objective of the study was to find the frequency of salivarygland tumours. Study Design: A descriptive study. Period: 1st Jan 2008 to 31st Dec 2010 (of 3years duration). Setting: ENT department Khyber Teaching Hospital and Surgical departmentHayatabad Medical Complex, Peshawar. Material and methods: Total number of 108 patientshaving salivary gland tumours enrolled from admitted patients in ENT department KhyberTeaching Hospital and Surgical department Hayatabad Medical Complex Peshawar. Thestudy was designed to find the frequency of salivary gland tumours. Results: In our studymost of the patients were having benign tumours (80.6%) with malignant counterpart in about19.4%. Overall the most common tumour was pleomorphic adenoma about 71.3% followed byMucoepidermoid 6.5%, adenoid cystic carcinoma 4.6% and Warthin’s tumour 4.6%. The mostcommonly involved salivary gland is parotid gland about 78.7% (85/108) with pleomorphicadenoma being the most common benign tumour and Mucoepidermoid the malignant variety.In submandibular gland/ sublingual glands the most common was pleomorphic adenomaand in minor salivary gland majority were malignant. Conclusion: Most of the salivary glandtumours are benign with majority of them are pleomorphic adenomas and parotid gland is themost common involved salivary gland.


2019 ◽  
Vol 57 (215) ◽  
Author(s):  
Prakash Khanal

Salivary gland tumours are relatively rare and constitute about 3-4 % of head and neck tumours. Most of the tumours arise from parotid glands. Submandibular gland tumours are very rare. Pleomorphic adenoma of the submandibular gland is exceedingly rare tumour. Very few studies have been reported in the literature that is exclusively conducted on pleomorphic adenoma affecting submandibular gland. Patients usually present with a slow growing, painless and mobile mass without any other associated symptoms. Radiologic studies are usually unable to differentiate benign from malignant tumours in most cases. Recurrence is rare with complete en bloc excision of the tumour along with submandibular gland. Prognosis is excellent except for the rare cases of malignant transformation. This paper describes a case of pleomorphic adenoma affecting submandibular gland with brief review of current literature on submandibular gland tumours. Keywords: pleomorphic adenoma; salivary gland; submandibular gland tumours.


Author(s):  
Edward Balai ◽  
Navdeep Bhamra ◽  
Karan Jolly

Salivary gland tumours are uncommon and account for just 6% of all head and neck neoplasms. Worldwide incidence varies, from 0.4 to 13.5 cases per 100 000 population. The parotid gland is by far the most commonly affected site, accounting for 80% of cases. The vast majority of these tumours are benign; only approximately 20–25% being malignant. This article considers the relevant clinical anatomy of the parotid gland, key aspects of assessment with history and examination, and when to refer to secondary care for further investigation. It will touch on the common benign and malignant parotid neoplasms and give an overview of secondary care management.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Grażyna Wyszyńska-Pawelec ◽  
Michał Gontarz ◽  
Jan Zapała ◽  
Mariusz Szuta

The aim of this retrospective study of 56 patients with minor salivary gland tumours (MSGTs) of the upper aerodigestive tract is to present demographic features, distribution of tumours as well as methods and results of treatment performed in our institution over a 10-year period. Of 221 patients with salivary gland tumours, 56 patients with MSGT were selected. There were 36 female and 20 male patients aged from 8 to 81 years. Male-to-female ratio was 1 : 2 in the group of benign MSGT and 1 : 1.7 in the group of malignant tumours. The palate was the most frequent site of MSGT (45.6%), followed by buccal mucosa (19.3%). Of all MSGTs 63.2% were malignant, and 36.8% were benign. Adenoid cystic carcinoma was the most common neoplasm (31.6%), followed by pleomorphic adenoma (29.8%). Surgery was the method of choice in the treatment of patients with MSGT. Postoperative defects were reconstructed by prosthetic obturators, local flaps, and free radial forearm flap. Relative survival for patients with malignant MSGT was 88% at three years and 71.5% at five years. MSGTs are more frequent in females and predominantly affect the palate. Malignant MSGTs are more common than benign.


2022 ◽  
Vol 3 (2) ◽  
pp. 1-15
Author(s):  
Junqian Zhang ◽  
Yingming Sun ◽  
Hongen Liao ◽  
Jian Zhu ◽  
Yuan Zhang

Radiation-induced xerostomia, as a major problem in radiation treatment of the head and neck cancer, is mainly due to the overdose irradiation injury to the parotid glands. Helical Tomotherapy-based megavoltage computed tomography (MVCT) imaging during the Tomotherapy treatment can be applied to monitor the successive variations in the parotid glands. While manual segmentation is time consuming, laborious, and subjective, automatic segmentation is quite challenging due to the complicated anatomical environment of head and neck as well as noises in MVCT images. In this article, we propose a localization-refinement scheme to segment the parotid gland in MVCT. After data pre-processing we use mask region convolutional neural network (Mask R-CNN) in the localization stage after data pre-processing, and design a modified U-Net in the following fine segmentation stage. To the best of our knowledge, this study is a pioneering work of deep learning on MVCT segmentation. Comprehensive experiments based on different data distribution of head and neck MVCTs and different segmentation models have demonstrated the superiority of our approach in terms of accuracy, effectiveness, flexibility, and practicability. Our method can be adopted as a powerful tool for radiation-induced injury studies, where accurate organ segmentation is crucial.


2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Asmaa Qureshi ◽  
Khalilur Rehman ◽  
Sohail Husain ◽  
Nasirul Hasan Khawaja ◽  
Ghulam Rasood Qureshi ◽  
...  

Salivary gland tumours make an important part of oral & maxillofacial pathology. Only few studies have been done in Pakistani population. The aim of this study was to describe morphological types of salivary gland tumours diagnosed at King Edward Medical College/ Mayo Hospital, Lahore during the years 1999-2001 and to compare their demographic data with those previously published. Material & Methods: This descriptive cross-sectional study was carried out at King Edward Medical College/ Mayo Hospital, Lahore. It reports 117 cases of salivary gland tumours diagnosed at Pathology Department during 1999-2001. Results: Of the 128 specimens of salivary glands, 117(91.4%) were confirmed as salivary neoplasms. Out of them, 62.7% were benign and 37.6% malignant and a slight female predominance (58.1%) was found. The most common location was the parotid gland (65.8%) followed by minor salivary glands (19.6%). Majority oft he t tumours was diagnosed during 3rd to 5 decades of life. Median age for benign tumours was 33 years (range 1-78) and a female predominance (58.9%) was seen again. Median age for malignant neoplasms was 45 years (range 9-70) with a female predilection ( 56.8%). However, 4 out o f 5 patients with Warthin`s tumour were men. Pleomorphic adenoma was the most frequent tumour (51.3%), followed by mucoepidermoid carcinoma (25.6%), adenoid cystic carcinoma (7.7)), Warthin`s tumour (4.3%) and monomorphic adenoma (2.6%). Two cases each of oncytoma & adenocarcinoma were recorded. Rare categories (single case each) of salivary tumours included lipoma, acinic cell carcinoma, basal cell adenoma, capillary haemangioma, metastatic carcinoma and non Hodgkin`s lymphoma. Conclusion: The principal site of salivary tumours was the parotid gland and females were most affected. Pleomorphic adenoma was the most frequent finding. The results of this study are comparable with other studies.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Anita Omhare ◽  
Sanjeev Kumar Singh ◽  
Jitendra Singh Nigam ◽  
Ankit Sharma

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.


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