ANALYSIS OF THE EFFECTIVENESS OF SELECTED SEGMENTATION METHODS OF ANATOMICAL BRAIN STRUCTURES

An important aspect of analysis medical images is acknowledging the role of the segmentation process of individual anatomical structures. This process allows to show the most important diagnostic details. Owing to the segmentation the areas of interest (ROI) it is possible to adapt the methods of further image analysis considering the specification of selected elements. This process has been widely used in medical diagnostics. The article presents the use of segmentation by thresholding, segmentation by region growth and by edge detection to extract the parts of the human brain the user is interested in. The series of MRI (magnetic resonance imaging) images were used. The aim of the research was to develop the methods that would allow comparing the effectiveness various types of anatomical brain structures’ segmentation in two dimensions. The above methods present the different impact that selected types of segmentation, masks or parameters have on the most accurate depiction of a selected human brain element.

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Construction of Anatomical Structure Specific Developmental Dynamical Networks for Human Brain on multiple Omics Levels

Current Bioinformatics ◽

10.2174/1574893616666210331115659 ◽

2021 ◽

Vol 16 ◽

Author(s):

Yingying Wang ◽

Yu Yang ◽

Jianfeng Liu ◽

Keshen Li

Keyword(s):

Human Brain ◽

Brain Development ◽

Brain Structures ◽

Developmental Time ◽

Anatomical Structure ◽

Dynamical Networks ◽

Anatomical Structures ◽

Developmental Networks ◽

Time Points ◽

Complex Processes

Background: Human brain development is a series of complex processes exhibiting profound changes from gestation to adulthood. Objective: We aimed to construct dynamic developmental networks for each anatomical structure of human brain based on omics’ levels in order to gain a new systematical brain map on molecular level. Method: We performed the brain development analyses by constructing dynamical networks between adjacent time points on different grouping levels of anatomical structures. The gene-time networks were first built to get the developing brain dynamical maps on transcriptome level. Then miRNA-mRNA networks and protein-protein networks were constructed by integrating the information from miRNomics and proteomics. The time and structure-specific biomarkers were filtered based on analyses of topological characters. Results: The most dramatical developmental time and structure were fetal-infancy and telencephalon, respectively. Cortex was the key developmental region in ‘late fetal and neonatal’ and ‘early infancy’. The development of temporal lobe was different from other lobes since the significant changes of molecules were found only in the comparison pair ‘early fetal-early mid-fetal’ and ‘adolescence-young adulthood’. Interestingly, the changes among different brain structures inside adolescence and adulthood were bigger than other time points. hsa-miR-548c-3p and H3C2 may be new brain developments indicators considering their key roles in networks. Conclusion: To our knowledge, this study is the first report of dynamical brain development maps for different anatomical structures on multiple omics’. The results provide a new sight of brain development in a systematical way which may provide a more accurate understanding of human brain.

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Human brain structures related to plantar vibrotactile stimulation: A functional magnetic resonance imaging study

NeuroImage ◽

10.1016/j.neuroimage.2005.08.052 ◽

2006 ◽

Vol 29 (3) ◽

pp. 923-929 ◽

Cited By ~ 43

Author(s):

Stefan M. Golaszewski ◽

Christian M. Siedentopf ◽

Florian Koppelstaetter ◽

Martin Fend ◽

Anja Ischebeck ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Functional Magnetic Resonance Imaging ◽

Human Brain ◽

Imaging Study ◽

Brain Structures ◽

Magnetic Resonance Imaging Study ◽

Functional Magnetic Resonance ◽

Resonance Imaging ◽

Vibrotactile Stimulation

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The role of imaging in computer assisted tumor surgery of the sacrum and pelvis.

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405617666210303105735 ◽

2021 ◽

Vol 17 ◽

Author(s):

Andrea Sambri ◽

Tomohiro Fujiwara ◽

Michele Fiore ◽

Claudio Giannini ◽

Riccardo Zucchini ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Computed Tomography ◽

Magnetic Resonance ◽

Preoperative Planning ◽

Preoperative Imaging ◽

Computer Assisted ◽

Tumor Surgery ◽

Resonance Imaging ◽

Anatomical Structures

: The use of a navigation system allows precise resection of a tumor and accurate reconstruction of the resultant defect thereby sparing important anatomical structures and preserving function. It is an “image-based” system where the imaging (computed tomography and magnetic resonance imaging) is required to supply the software with data. The fusion of the preoperative imaging provides pre-operative information about local anatomy and extent of the tumor, so that it allows an accurate preoperative planning. Accurate pre-operative imaging is mandatory in order to minimize CATS errors, thus performing accurate tumor resections.

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Selection and Preparation of Specific Tissue Regions For Tem Using Large Epoxy-Embedded Blocks

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010007206x ◽

1973 ◽

Vol 31 ◽

pp. 324-325 ◽

Cited By ~ 1

Author(s):

P. M. Lowrie ◽

W. S. Tyler

Keyword(s):

Electron Microscopy ◽

Anatomical Structures ◽

Ultrastructural Studies ◽

Transmission Electron ◽

Microscopic Evaluation ◽

Embedded Blocks ◽

Specific Tissue ◽

Definition Of ◽

Areas Of Interest ◽

Selection Of

The importance of examining stained 1 to 2μ plastic sections by light microscopy has long been recognized, both for increased definition of many histologic features and for selection of specimen samples to be used in ultrastructural studies. Selection of specimens with specific orien ation relative to anatomical structures becomes of critical importance in ultrastructural investigations of organs such as the lung. The uantity of blocks necessary to locate special areas of interest by random sampling is large, however, and the method is lacking in precision. Several methods have been described for selection of specific areas for electron microscopy using light microscopic evaluation of paraffin, epoxy-infiltrated, or epoxy-embedded large blocks from which thick sections were cut. Selected areas from these thick sections were subsequently removed and re-embedded or attached to blank precasted blocks and resectioned for transmission electron microscopy (TEM).

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