Acoustic Pharyngometry Measurement of Minimal Cross-Sectional Airway Area Is a Significant Independent Predictor of Moderate-To-Severe Obstructive Sleep Apnea

Efficient screening for severe obstructive sleep apnea (OSA) is important for children with snoring before time-consuming standard polysomnography. This retrospective cross-sectional study aimed to compare clinical variables, home snoring sound analysis, and home sleep pulse oximetry on their predictive performance in screening severe OSA among children who habitually snored. Study 1 included 9 (23%) girls and 30 (77%) boys (median age of 9 years). Using univariate logistic regression models, 3% oxygen desaturation index (ODI3) ≥ 6.0 events/h, adenoidal-nasopharyngeal ratio (ANR) ≥ 0.78, tonsil size = 4, and snoring sound energy of 801–1000 Hz ≥ 22.0 dB significantly predicted severe OSA in descending order of odds ratio. Multivariate analysis showed that ODI3 ≥ 6.0 events/h independently predicted severe pediatric OSA. Among several predictive models, the combination of ODI3, tonsil size, and ANR more optimally screened for severe OSA with a sensitivity of 91% and a specificity of 94%. In Study 2 (27 (27%) girls and 73 (73%) boys; median age, 7 years), this model was externally validated to predict severe OSA with an accuracy of 76%. Our results suggested that home sleep pulse oximetry, combined with ANR, can screen for severe OSA more optimally than ANR and tonsil size among children with snoring.

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Relation of elastic properties of pulmonary artery with left ventricular abnormalities and aortic stiffness in patients with moderate to severe obstructive sleep apnea: A cross-sectional echocardiographic study

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology ◽

10.5543/tkda.2015.67862 ◽

2016 ◽

Author(s):

Ibrahim Halil Altıparmak

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Pulmonary Artery ◽

Elastic Properties ◽

Aortic Stiffness ◽

Left Ventricular ◽

Severe Obstructive Sleep Apnea ◽

Cross Sectional ◽

Echocardiographic Study ◽

Obstructive Sleep

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Nocturia is an independent predictor of severe obstructive sleep apnea in patients with ischemic stroke

Journal of Neurology ◽

10.1007/s00415-010-5705-2 ◽

2010 ◽

Vol 258 (2) ◽

pp. 189-194 ◽

Cited By ~ 12

Author(s):

Chung-Yao Chen ◽

Chih-Chin Hsu ◽

Yu-Cheng Pei ◽

Chung-Chieh Yu ◽

Ying-Syuan Chen ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Ischemic Stroke ◽

Sleep Apnea ◽

Independent Predictor ◽

Severe Obstructive Sleep Apnea ◽

Obstructive Sleep

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Postoperative monitoring of children with obstructive sleep apnea syndrome

Orvosi Hetilap ◽

10.1556/oh.2014.29879 ◽

2014 ◽

Vol 155 (18) ◽

pp. 703-707 ◽

Cited By ~ 1

Author(s):

Pálma Benedek ◽

Gabriella Kiss ◽

Eszter Csábi ◽

Gábor Katona

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Obstructive Sleep Apnea Syndrome ◽

Preoperative Evaluation ◽

Sleep Apnea Syndrome ◽

Study Patient ◽

Severe Obstructive Sleep Apnea ◽

Obstructive Sleep ◽

Significant Difference ◽

Apnea Syndrome

Introduction: Treatment of pediatric obstructive sleep apnea syndrome is surgical. The incidence of postoperative respiratory complications in this population is 5–25%. Aim: The aim of the authors was to present the preoperative evaluation and monitoring procedure elaborated in Heim Pál Children Hospital, Budapest. Method: 142 patients were involved in the study. Patient history was obtained and physical examination was performed in all cases. Thereafter, polysomnography was carried out, the severity of the obstructive sleep apnea syndrome was determined, and the patients underwent tonsilloadenotomy. Results: 45 patients with mild, 50 patients with moderate and 47 patients with severe obstructive sleep apnea syndrome were diagnosed. There was no complication in patients with mild disease, while complications were observed in 6 patients in the moderate group and 24 patients in the severe group (desaturation, apnea, stridor, stop breathing) (p<0.000). In patients with severe obstructive sleep apnea syndrome, no significant difference was noted in preoperative apnoea-hypapnea index (p = 0.23) and in nadir oxygen saturation values (p = 0.73) between patients with and without complication. Conclusions: Patients with severe obstructive sleep apnea syndrome should be treated in hospital where pediatric intensive care unit is available. Orv. Hetil., 2014, 155(18), 703–707.

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Predictive Factors for Efficacious Oral Appliance Therapy in Moderate to Severe Obstructive Sleep Apnea Patients

The Laryngoscope ◽

10.1002/lary.29439 ◽

2021 ◽

Author(s):

Guillaume Buiret ◽

Maroun Bechara ◽

Isabelle Plouin‐Gaudon ◽

Frederique Bavozet ◽

Olivia Dancea ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Predictive Factors ◽

Oral Appliance ◽

Severe Obstructive Sleep Apnea ◽

Oral Appliance Therapy ◽

Obstructive Sleep

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Risk of mortality among patients with moderate to severe obstructive sleep apnea and diabetes mellitus: results from the SantOSA cohort

Sleep And Breathing ◽

10.1007/s11325-020-02283-y ◽

2021 ◽

Author(s):

Gonzalo Labarca ◽

Jorge Dreyse ◽

Constanza Salas ◽

Alexia Schmidt ◽

Francisca Rivera ◽

...

Keyword(s):

Diabetes Mellitus ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Severe Obstructive Sleep Apnea ◽

Risk Of Mortality ◽

Obstructive Sleep

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Continuous Positive Airway Pressure-Mandibular Advancement Device Combination Therapy for Moderate-to-Severe Obstructive Sleep Apnea: A Preliminary Study

European Journal of Dentistry ◽

10.1055/s-0040-1719220 ◽

2021 ◽

Author(s):

Thyagaseely Sheela Premaraj ◽

Jacob Stadiem ◽

Shyamaly Arya Premaraj ◽

Charles R. Davies ◽

Matthew Dennis ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Daytime Sleepiness ◽

Airway Pressure ◽

Positive Airway Pressure ◽

Mandibular Advancement Device ◽

Mandibular Advancement ◽

Severe Obstructive Sleep Apnea ◽

Obstructive Sleep ◽

The Mean

Abstract Objectives The purpose of this pilot study was to determine whether compliance to auto-adjusting positive airway pressure (APAP) improves with the addition of a mandibular advancement device (MAD). Secondary outcome measures included were APAP pressure, subjective daytime sleepiness, apnea–hypopnea index (AHI), and mask leaks. Setting and Sample Population Participants included were diagnosed with moderate-to-severe obstructive sleep apnea (OSA) and became noncompliant to prescribed APAP. Thirteen participants with a mean age of 61.6 years were recruited for this study. Materials and Methods All participants were given a MAD to use with their APAP. Parameters measured included APAP pressure, AHI, mask leak reported via ResMed AirViewTM software, and self-reported daytime sleepiness (Epworth Sleepiness Scale [ESS]). A paired two-sample for mean t-test was performed to determine significance. Results The mean difference of pre- and postintervention APAP compliance was 23.1%, which was statistically significant (p = 0.015). The mean APAP air pressures were unchanged. The difference between pre- and postintervention mean ESS scores was 1.4 and was statistically significant (p = 0.027). The mean difference between pre- and postintervention AHI values and mask leak showed no significant difference. Conclusion This study showed that combination of APAP-MAD therapy, for patients with moderate-to-severe OSA who were noncompliant to APAP use, significantly increased compliance with APAP therapy, and significantly decreased the daytime sleepiness of participants.

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