Zinc and vitamin A supplementation in Indigenous Australian children hospitalised with lower respiratory tract infection: a randomised controlled trial

2006 ◽  
Vol 184 (3) ◽  
pp. 107-112 ◽  
Author(s):  
Anne B Chang ◽  
Paul J Torzillo ◽  
Peter M Stewart ◽  
Naomi C Boyce ◽  
Andrew V White ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Tract Infection ◽  
Vitamin A ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Controlled Trial ◽  
Indigenous Australian ◽  
Vitamin A Supplementation ◽  
Randomised Controlled

scholarly journals Oral prednisolone for acute lower respiratory tract infection in clinically unrecognised asthma: an exploratory analysis of the Oral Steroids for Acute Cough (OSAC) randomised controlled trial

BJGP Open ◽  
2020 ◽  
Vol 4 (5) ◽  
pp. bjgpopen20X101099
Author(s):  
Sean Hawkey ◽  
Grace J Young ◽  
Paul Little ◽  
Michael Moore ◽  
Alastair D Hay
Keyword(s):  
Primary Care ◽  
Randomised Controlled Trial ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Symptom Severity ◽  
Lower Respiratory Tract ◽  
Controlled Trial ◽  
Acute Cough ◽  
Oral Steroids ◽  
Randomised Controlled

BackgroundAcute lower respiratory tract infection (ALRTI) is often treated in primary care with antibiotics. The recent Oral Steroids for Acute Cough (OSAC) randomised controlled trial (RCT) showed corticosteroids were not an effective alternative in adults without a diagnosis of asthma with ALRTI.AimTo investigate if corticosteroids are beneficial for ALRTI in patients with unrecognised asthma.Design & settingAn exploratory analysis was undertaken of the primary care OSAC trial.MethodA subgroup analysis was performed in patients who responded ‘yes’ to the following International Primary Care Airways Group (IPCAG) question: did you have wheeze and/or at least two of nocturnal cough or chest tightness or dyspnoea in the past year. Sensitivity analyses were carried out on those who answered ‘yes’ to wheeze and at least two of the nocturnal symptoms. The primary outcomes were as follows: duration of cough (0–28 days, minimum clinically important difference [MCID] of 3.79 days) and mean symptom severity score (range 0–6; MCID 1.66 units).ResultsIn total, 40 (10%) patients were included in the main analysis: mean age 49 years (standard deviation [SD] = 17.9), 52% male. Median cough duration was 3 days in both prednisolone (interquartile range [IQR] = 2–6 days) and placebo (IQR = 1–6 days) groups (adjusted hazard ratio [HR] = 1.10; 95% confidence interval [CI] = 0.47 to 2.54; P = 0.83), equating to 0.24 days longer in the prednisolone group (95% CI = 1.23 days shorter to 2.88 days longer). Mean symptom severity difference was –0.14 (95% CI = –0.78 to 0.49; P=0.65) comparing prednisolone with placebo. Similar findings were found in the sensitivity analysis.ConclusionNo evidence was found to support the use of corticosteroids for ALRTI in patients with clinically unrecognised asthma. Clinicians should not use the IPCAG questions to target oral corticosteroid treatment in patients with ALRTI.

scholarly journals Efek suplementasi vitamin A pada ibu nifas terhadap pertumbuhan bayi umur 0-4 bulan

2013 ◽  
Vol 9 (3) ◽  
pp. 97
Author(s):  
Abdullah Abdullah ◽  
Endy Paryanto Prawirohartono ◽  
Siti Helmyati
Keyword(s):  
Tract Infection ◽  
Vitamin A ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Respiratory Infections ◽  
Vitamin A Deficiency ◽  
Controlled Trial ◽  
Acute Respiratory Tract Infection ◽  
Vitamin A Supplementation ◽  
Education Group

Background: Vitamin A deficiency is a nutritional problem in infants since breastmilk insufficiently contains vitamin A. Therefore it is necessary to study the effect of vitamin A supplementation to mothers at parturition period on growth and morbidities of infants at 0-4 months of age.Objective: To identify the effect of vitamin A supplementation to mothers at parturition period on growth and morbidities of infants at 0-4 months of age.Method: We conducted a randomized controlled trial from March-July 2009 at Province of Lampung. We recruited 90 mothers that were grouped into vitamin A supplementation group and socialization about vitamin A group during parturition period. The outcomes of this study were growth in WHZ and morbidities of infants at 0-4 months of age measured as duration of acute diarrhea and upper respiratory infections. Statistical analysis was performed by using Chi-Square and t-test.Results: The growth of infants of 0-4 months from vitamin A supplemented mothers was not significantly different from the socialization group. Duration of diarrhea and acute respiratory tract infection of infants from supplemented mothers at parturition period was significantly shorter than of infants from socialization group.Conclusion: The growth of infant at 0-4 months of age from vitamin A supplemented mothers at parturition period were not significantly different from those who were from education group. Duration of diarrhea and acute respiratory tract infection of infants from vitamin A supplemented mothers at parturition period were shorter than those who were from education group.

Effect of vitamin A supplementation on diarrhoea and acute respiratory tract infection in children

1994 ◽  
Vol 10 (1) ◽  
pp. 57-61 ◽  
Author(s):  
R. Biswas ◽  
A. B. Biswas ◽  
B. Manna ◽  
S. K. Bhattacharya ◽  
R. Dey ◽  
...  
Keyword(s):  
Tract Infection ◽  
Vitamin A ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Vitamin A Supplementation
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