Rapid detection, toxicosurveillance and public health response to stimulant adulteration with acetyl fentanyl

2021 ◽  
Author(s):  
Varan Perananthan ◽  
Chris Tremonti ◽  
Emily Nash ◽  
Thanjira Jiranantakan ◽  
Andrew H Dawson
Keyword(s):  
Public Health ◽  
Rapid Detection ◽  
Public Health Response ◽  
Health Response ◽  
Acetyl Fentanyl

Psychology's role in the public health response to assaultive violence among young African-American men.

1993 ◽  
Vol 48 (2) ◽  
pp. 142-154 ◽  
Author(s):  
W. Rodney Hammond ◽  
Betty Yung
Keyword(s):  
Public Health ◽  
African American ◽  
African American Men ◽  
Public Health Response ◽  
The Public ◽  
Health Response

School-Based Interventions and a Public Health Response to Complex Trauma in Children

2010 ◽  
Author(s):  
Christopher Blodgett ◽  
Roy Harrington ◽  
Natalie Turner
Keyword(s):  
Public Health ◽  
Complex Trauma ◽  
Public Health Response ◽  
School Based ◽  
Health Response ◽  
School Based Interventions

You're not alone: A public health response to immigrant/refugee distress in the current sociopolitical context.

2020 ◽  
Vol 17 (S1) ◽  
pp. 128-138 ◽  
Author(s):  
Rebecca E. Ford-Paz ◽  
Catherine DeCarlo Santiago ◽  
Claire A. Coyne ◽  
Claudio Rivera ◽  
Sisi Guo ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Response ◽  
Health Response ◽  
Sociopolitical Context

Responsibility and Blame

2018 ◽  
Author(s):  
Joshua M. Sharfstein
Keyword(s):  
Public Health ◽  
Health Agency ◽  
Public Health Response ◽  
Difficult Situation ◽  
Health Training ◽  
Health Response ◽  
Public Health Training ◽  
Health Agencies ◽  
Sincere Apology

Issues of responsibility and blame are very rarely discussed in public health training, but are seldom forgotten in practice. Blame often follows a crisis, and leaders of health agencies should be able to think strategically about how to handle such accusations before being faced with the pain of dealing with them. When the health agency is not at all at fault, officials can make the case for a strong public health response without reservation. When the agency is entirely to blame, a quick and sincere apology can allow the agency to retain credibility. The most difficult situation is when the agency is partly to blame. The goal in this situation is to accept the appropriate amount of blame while working quickly to resolve the crisis.

Gender and the overdose crisis in North America: Moving past gender-neutral approaches in the public health response

2019 ◽  
Vol 69 ◽  
pp. 43-45 ◽  
Author(s):  
Alexandra B. Collins ◽  
Geoff Bardwell ◽  
Ryan McNeil ◽  
Jade Boyd
Keyword(s):  
Public Health ◽  
North America ◽  
Public Health Response ◽  
The Public ◽  
Health Response ◽  
Gender Neutral

scholarly journals Evaluating the accuracy of Listeria monocytogenes assemblies from quasimetagenomic samples using long and short reads

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Seth Commichaux ◽  
Kiran Javkar ◽  
Padmini Ramachandran ◽  
Niranjan Nagarajan ◽  
Denis Bertrand ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Response ◽  
High Quality ◽  
Short Read ◽  
Short Reads ◽  
The Core ◽  
Long Reads ◽  
Health Response ◽  
Long Read ◽  
Core Genes

Abstract Background Whole genome sequencing of cultured pathogens is the state of the art public health response for the bioinformatic source tracking of illness outbreaks. Quasimetagenomics can substantially reduce the amount of culturing needed before a high quality genome can be recovered. Highly accurate short read data is analyzed for single nucleotide polymorphisms and multi-locus sequence types to differentiate strains but cannot span many genomic repeats, resulting in highly fragmented assemblies. Long reads can span repeats, resulting in much more contiguous assemblies, but have lower accuracy than short reads. Results We evaluated the accuracy of Listeria monocytogenes assemblies from enrichments (quasimetagenomes) of naturally-contaminated ice cream using long read (Oxford Nanopore) and short read (Illumina) sequencing data. Accuracy of ten assembly approaches, over a range of sequencing depths, was evaluated by comparing sequence similarity of genes in assemblies to a complete reference genome. Long read assemblies reconstructed a circularized genome as well as a 71 kbp plasmid after 24 h of enrichment; however, high error rates prevented high fidelity gene assembly, even at 150X depth of coverage. Short read assemblies accurately reconstructed the core genes after 28 h of enrichment but produced highly fragmented genomes. Hybrid approaches demonstrated promising results but had biases based upon the initial assembly strategy. Short read assemblies scaffolded with long reads accurately assembled the core genes after just 24 h of enrichment, but were highly fragmented. Long read assemblies polished with short reads reconstructed a circularized genome and plasmid and assembled all the genes after 24 h enrichment but with less fidelity for the core genes than the short read assemblies. Conclusion The integration of long and short read sequencing of quasimetagenomes expedited the reconstruction of a high quality pathogen genome compared to either platform alone. A new and more complete level of information about genome structure, gene order and mobile elements can be added to the public health response by incorporating long read analyses with the standard short read WGS outbreak response.

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