Comparison of a Validated LC/MS/MS Method with a Validated GC/MS Method for the Analysis of Zeranol and its Related Mycotoxin Residues in Bovine Urine Samples Collected During Argentina's Residue Monitoring Control Program (2005–2012)

2014 ◽  
Vol 97 (5) ◽  
pp. 1470-1475 ◽  
Author(s):  
Juan M. Echarte ◽  
Damián C. Fernández ◽  
Carlos A. Chiacchio ◽  
Verónica M. Torres Leedham
2007 ◽  
Vol 28 (3) ◽  
pp. 337-347 ◽  
Author(s):  
Masekonyela Linono Damane Sebotsa ◽  
André Dannhauser ◽  
Pieter L. Jooste ◽  
Gina Joubert

Background Evaluation of the sustainability of iodine-deficiency disorders control programs guarantees successful and sustained virtual elimination of iodine deficiency. The Lesotho universal salt iodization legislation was enacted in 2000 as an iodine-deficiency disorders control program and has never been evaluated. Objectives To assess the sustainability of the salt iodization program in Lesotho, 2 years after promulgation of the universal salt iodization legislation. Methods The proportion to population size method of sampling was used in 2002 to select 31 clusters in all ecological zones and districts of Lesotho. In each cluster, 30 women were selected to give urine and salt samples and 30 schoolchildren to give urine samples. The salt samples were analyzed by the iodometric titration method, and the ammonium persulfate method was used to analyze the urine samples. The chairperson of the iodine-deficiency disorders control program was interviewed on programmatic indicators of sustainability. SAS software was used for statistical analysis of the data. Results The urinary iodine concentrations of very few children (10.1% and 21.5%) and women (9.8% and 17.9%) were lower than 50 μg/L and 100 μg/L, respectively. At the household level, 86.9% of the households used adequately iodized salt. Only four indicators of sustainability have been attained by the salt iodization program in Lesotho. Conclusions Iodine-deficiency disorders have been eliminated as a public health problem in Lesotho, but this elimination is not sustainable. Effective regular monitoring of salt iodine content at all levels, with special attention to iodization of coarse salt, is recommended, together with periodic evaluation of the iodization program.


The Analyst ◽  
2014 ◽  
Vol 139 (18) ◽  
pp. 4702-4709 ◽  
Author(s):  
Matías Regiart ◽  
Sirley V. Pereira ◽  
Viviana G. Spotorno ◽  
Franco A. Bertolino ◽  
Julio Raba

This study reports an accurate and sensitive strategy for zeranol (ZER) determination in bovine urine samples.


2001 ◽  
Vol 84 (4) ◽  
pp. 1025-1030 ◽  
Author(s):  
Simon A Haughey ◽  
G Andrew Baxter ◽  
Christopher T Elliott ◽  
Bjorn Persson ◽  
Carin Jonson ◽  
...  

Abstract Clenbuterol (CBL) is an orally active β2-adrenoceptor agonist which has been used in veterinary medicine as a broncodilator and an agent of uterine relaxation. It has however become better known as a drug used illegally to promote growth in farm animals. A rapid an sensitive biosensor assay was developed to detect CBL residues in bovine urine. The method involved a simple extraction procedure using tert-butyl methyl ether followed by analysis on the biosensor with results obtained against a buffer calibration curve. The assay allowed up to 88 samples to be analyzed per working day, with each cycle on the biosensor taking approximately 7 min to complete. The limit of detection (LOD) was determined as 0.27 ng/mL using 20 EU reference blank urine samples. The intra-assay Sr ranged from 4.7–7.6% for 3 control samples while the interassay Sr ranged from 9.2–12.7%. The recovery was found to be approximately 95%. A series of incurred urine samples were assayed and the results compared by Enzyme immunoassay (EIA), radio-immunoassay (RIA), and gas chromatography/mass spectrometry (GC/MS) analysis.Urine samples taken from local abattoirs were also analyzed by the biosensor method and by EIA analysis. The antibody used in the biosensor test exhibited high cross reactivity with at least 7 other β-agonists allowing detection of these compounds at less than 1 ng/mL in bovine urine.


2005 ◽  
Vol 66 (5) ◽  
pp. 762-766 ◽  
Author(s):  
Junpen Suwimonteerabutr ◽  
Wanpen Chaicumpa ◽  
Patcharin Saengjaruk ◽  
Pramuan Tapchaisri ◽  
Manas Chongsa-nguan ◽  
...  

2012 ◽  
Vol 56 (4) ◽  
pp. 611-615 ◽  
Author(s):  
Barbara Woźniak ◽  
Sebastian Witek ◽  
Jan Żmudzki ◽  
Alicja Kłopot

Abstract Natural occurrence of thiouracil in bovine and swine urine in Poland was investigated. Under the national residue control programme, 537 urine samples were tested. In 77 samples (14.3%) thiouracil was detected above decision limit CCα (0.91 μg L-1), including eight samples over the recommended concentration of 10 μg L-1. Of the bovine urine samples, 95 and 99 percentiles have thiouracil concentration below 4.50 and 14.85 μg L-1 ,and of porcine samples below 2.35 and 6.80 μg L-1, respectively.


2009 ◽  
Vol 637 (1-2) ◽  
pp. 321-327 ◽  
Author(s):  
Lisa Connolly ◽  
Kai Cai ◽  
Edwige Van der Heiden ◽  
Marie-Louise Scippo ◽  
Marc Muller ◽  
...  

Author(s):  
William F. Chambers ◽  
Arthur A. Chodos ◽  
Roland C. Hagan

TASK8 was designed as an electron microprobe control program with maximum flexibility and versatility, lending itself to a wide variety of applications. While using TASKS in the microprobe laboratory of the Los Alamos National Laboratory, we decided to incorporate the capability of using subroutines which perform specific end-member calculations for nearly any type of mineral phase that might be analyzed in the laboratory. This procedure minimizes the need for post-processing of the data to perform such calculations as element ratios or end-member or formula proportions. It also allows real time assessment of each data point.The use of unique “mineral codes” to specify the list of elements to be measured and the type of calculation to perform on the results was first used in the microprobe laboratory at the California Institute of Technology to optimize the analysis of mineral phases. This approach was used to create a series of subroutines in TASK8 which are called by a three letter code.


Sign in / Sign up

Export Citation Format

Share Document