Prevention of Sexually Transmitted HIV Infection

Background: Sexually transmitted infections (STIs) are the most well established risk factors for the spread of HIV infection. STIs act as cofactors and facilitators for HIV transmission. The effects of HIV infection on immunity can increase susceptibility to other STIs. The aims and objectives of the study were to determine the prevalence of co-infection of sexually transmitted infections among people living with HIV and AIDS.Methods: A retrospective chart review of the data collected from the clinical records of all HIV patients who had attended the STI clinic of Chengalpattu Medical College, Chengalpattu, Tamil Nadu during the five years period, from January 2013 to December 2017, was carried out. Demographic data, clinical manifestations, co-infection of STIs among HIV patients, laboratory investigations and treatment were collected. The data collected were computed and analyzed statistically.Results: During the study period of 5 years from 2013 to 2017 the total number of patients attended the STI clinic were 10825, among that males were 4534 (41.88%) and females were 6291 (58.12%). STIs/RTIs were seen in 2560 (23.65%) cases among the total number of patients attended. HIV was found to be positive in 294 cases, in that 168 (57.15%) were males and 126 (42.85%) were females. In male HIV patients, 51 (30.36%) had co-infection with other STIs/RTIs. In female HIV patients, 57 (45.24) % had co-infection with other STIs/RTIs. Viral STIs was the common co-infection seen in males and vaginal cervical discharge was common in females.Conclusions: STI/RTI co-infection, both symptomatic and asymptomatic are common among PLHIV. Hence they should be regularly counselled regarding the significance of periodic screening for STI/RTIs avoidance of high risk sexual behaviour.

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Mujeres con VIH-SIDA en el Hospital Nacional Cayetano Heredia en Lima, Perú.

Revista Medica Herediana ◽

10.20453/rmh.v10i2.623 ◽

2013 ◽

Vol 10 (2) ◽

pp. 62

Author(s):

Lely SOLARI ZERPA ◽

Luis Miguel VALDEZ ◽

Juan ECHEVARRIA ZARATE ◽

Eduardo GOTUZZO HERENCIA

Keyword(s):

Hiv Infection ◽

Drug Users ◽

Pneumocystis Carinii ◽

Retrospective Chart Review ◽

Sexual Practices ◽

Heterosexual Transmission ◽

Sexual Life ◽

Heterosexual Intercourse ◽

Sexually Transmitted ◽

Wasting Syndrome

Objective: The aim of this study is to describe the epidemiological and clinical characteristics of the women infected with the Human Inmunodefficiency Virus (HIV) who were seen at the Hospital Nacional Cayetano Heredia from January 1989 to December 1996. Material and Methods: We did a retrospective chart review of their demographic and medical registers. We used the Centres for Disease Control (CDC) classification for the HIV infection. (Stages I-IV). Results: We included 236 women, from 17 to 60 years old, with a mean age of 30.4 years. The number of diagnosed cases per year of infected women increased from 5 in 1989 to 63 in 1996. The probable means of acquisition of infection was heterosexual intercourse in 212 patients (90.2%). Only had one sexual partner in her life 113 (47.8%) of the patients seen. There were 4 (1.6%) sexual workers and there were no intravenous drug users. A percentage of 23.4% have had other Sexually Transmitted Diseases (STD), and these were more prevalent in women who had risky sexual practices (p=0.005). Out of the 236, 69 women had diagnosis of Acquired Inmunodefficiency Syndrome (AIDS) The most frequent AIDS-defining condition was the Wasting Syndrome in 23 women (33.3%). There were 19 deaths within the study period. The mean survival time after the AIDS diagnosis was 10.6 months and the most frequent death cause was Tuberculosis and Pneumocystis carinii Pneumonia. Conclusion: The fact of having a predominantly heterosexual transmission and that there is a high percentage of monogamous women and women with few sexual partners make us suppose that it is probably their partners risk sexual behavior what exposes women to HIV infection. We must underline the importance of an adequate information to women who start their sexual life and of the risks these bring, and the diffusion of the use of condoms to prevent this infection.

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Randomized Controlled Pilot Study of Antiretrovirals and a Behavioral Intervention for Persons With Acute HIV Infection: Opportunity for Interrupting Transmission

Open Forum Infectious Diseases ◽

10.1093/ofid/ofy341 ◽

2018 ◽

Vol 6 (1) ◽

Cited By ~ 1

Author(s):

William C Miller ◽

Sarah E Rutstein ◽

Sam Phiri ◽

Gift Kamanga ◽

Dominic Nsona ◽

...

Keyword(s):

Pilot Study ◽

Hiv Infection ◽

Behavioral Intervention ◽

Sexually Transmitted Infection ◽

Health Benefit ◽

Acute Hiv Infection ◽

Transmitted Infection ◽

Sexually Transmitted ◽

Randomized Controlled ◽

Acute Hiv

Abstract Background Persons with acute HIV infection (AHI) have heightened transmission risk. We evaluated potential transmission reduction using behavioral and biomedical interventions in a randomized controlled pilot study in Malawi. Methods Persons were randomized 1:2:2 to standard counseling (SC), 5-session behavioral intervention (BI), or behavioral intervention plus 12 weeks of antiretrovirals (ARVs; BIA). All were followed for 26–52 weeks and, regardless of arm, referred for treatment according to Malawi-ARV guidelines. Participants were asked to refer partners for testing. Results Among 46 persons (9 SC, 18 BI, 19 BIA), the average age was 28; 61% were male. The median viral load (VL) was 5.9 log copies/mL at enrollment. 67% (10/15) of BIA participants were suppressed (<1000 copies/mL) at week 12 vs 25% BI and 50% SC (P = .07). Although the mean number of reported condomless sexual acts in the past week decreased from baseline across all arms (1.5 vs 0.3 acts), 36% experienced incident sexually transmitted infection by 52 weeks (12% SC, 28% BI, 18% BIA). Forty-one percent (19/46) of participants referred partners (44% SC, 44% BI, 37% BIA); 15 of the partners were HIV-infected. Conclusions Diagnosis of AHI facilitates behavioral and biomedical risk reduction strategies during a high-transmission period that begins years before people are typically identified and started on ARVs. Sexually transmitted infection incidence in this cohort suggests ongoing risk behaviors, reinforcing the importance of early intervention with ARVs to reduce transmission. Early diagnosis coupled with standard AHI counseling and early ARV referral quickly suppresses viremia, may effectively change behavior, and could have tremendous public health benefit in reducing onward transmission.

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