scholarly journals Complications and Solutions for Post-Operative Liposuction Deformities

2021 ◽  
Author(s):  
Chris W. Robb ◽  
Michael H. Gold
Keyword(s):  
General Anesthesia ◽  
Real World ◽  
Tumescent Anesthesia ◽  
Treatment Practices ◽  
Safety Concerns

In this chapter, the authors will review the complications associated with liposuction and laser liposuction procedures, using published reports as the guide to document these complications and deformities to the readers. In addition, the authors will also report on the use of tumescent anesthesia and the published documentation regarding safety concerns that have been presented via the use of tumescence versus general anesthesia when performing liposuction or laser liposuction. Real-world discussions also will take place in which the authors describe best treatment practices as solutions to those complications described. Liposuction and laser liposuction are wonderful procedures that have been performed for many years. Understanding and being able to identify and treat any untoward complications is extremely important to make everyone a better surgeon and a better physician.

General Anesthesia may have Similar Outcomes with Conscious Sedation in Thrombectomy Patients with Acute Ischemic Stroke: A Real-World Registry in China

2018 ◽  
Vol 80 (1-2) ◽  
pp. 7-13 ◽  
Author(s):  
Wanying Shan ◽  
Dong Yang ◽  
Huaiming Wang ◽  
Liang Xu ◽  
Meng Zhang ◽  
...  
Keyword(s):  
Propensity Score ◽  
Endovascular Treatment ◽  
General Anesthesia ◽  
Real World ◽  
Conscious Sedation ◽  
Propensity Score Analysis ◽  
Stroke Patients ◽  
Anterior Circulation ◽  
Score Analysis ◽  
Symptomatic Intracranial Hemorrhage

Background and Purpose: Clinical trials showed that anesthesia may not influence the functional outcome in stroke patients with endovascular therapy; however, data are lacking in China. Using real-world registry data, our study aims to compare the effects of general anesthesia or conscious sedation on functional outcomes in stroke patients treated with thrombectomy in China. Methods: Consecutive patients with acute anterior circulation stroke receiving thrombectomy in 21 stroke centers between January 2014 and June 2016 were included in this study. The propensity score analysis with 1: 1 ratio was used to match the baseline variables between patients with general anesthesia and the conscious sedation. The 90-day modified Rankin Scale (mRS), symptomatic intracranial hemorrhage (sICH), and death were compared between groups. Results: Of the 698 patients undergoing endovascular treatment, 138 were treated with general anesthesia and 560 with conscious sedation. After propensity score matching, 114 general anesthesia and 114 conscious sedation patients were matched. The proportions of patients with 90-day mRS 0–2 were not significantly different between general anesthesia and conscious sedation groups (41.2% [47/114] vs. 46.5% [53/114], p = 0.470), nor were the rates of sICH (21.9% [25/114] vs. 12.3% [14/114], p = 0.072) and 90-day mortality (31.6% [36/114] vs. 21.9% [25/114], p = 0.145). Conclusion: Anesthesia patterns may have no significant impacts on clinical outcomes in patients with acute anterior circulation occlusion stroke undergoing endovascular treatment in the real-world practice in China.

Relapsed/refractory primary mediastinal large B-cell lymphoma: a structured review of epidemiology, treatment guidelines and real-world treatment practices

2020 ◽  
Vol 13 (3) ◽  
pp. 275-287
Author(s):  
Jitender Takyar ◽  
Monika Raut ◽  
Rebekah Borse ◽  
Arun Balakumaran ◽  
Manu Sehgal
Keyword(s):  
B Cell ◽  
Real World ◽  
Treatment Guidelines ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Treatment Practices ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Real World Treatment Practices for Mantle Cell Lymphoma in Japan: An Observational Database Research Study (CLIMBER-DBR)

2021 ◽  
Author(s):  
Koji Izutsu ◽  
Junji Suzumiya ◽  
Jun Takizawa ◽  
Kenjiro Fukase ◽  
Maki Nakamura ◽  
...  
Keyword(s):  
Mantle Cell Lymphoma ◽  
Real World ◽  
Research Study ◽  
Cell Lymphoma ◽  
Treatment Practices ◽  
Observational Database ◽  
Database Research ◽  
Mantle Cell

Author response for "Safety concerns of SGLT‐2 inhibitors in type 1 diabetes: a real‐world study from the perspective of FAERS"

2020 ◽  
Author(s):  
Xiang Zhou ◽  
Yangzhong Zhou ◽  
Xuemei Li ◽  
Xinhua Xiao
Keyword(s):  
Type 1 Diabetes ◽  
Real World ◽  
Author Response ◽  
Safety Concerns

A Comparative Study of the Efficacy of Endovenous Laser Treatment of the Incompetent Great Saphenous Under General Anesthesia with External Air Cooling with and Without Tumescent Anesthesia

2013 ◽  
Vol 39 (2) ◽  
pp. 255-262 ◽  
Author(s):  
Esteban HernÁndez Osma ◽  
Serge R. Mordon ◽  
Mohamad Feras Marqa ◽  
Jiri Vokurka ◽  
Mario A. Trelles
Keyword(s):  
Comparative Study ◽  
General Anesthesia ◽  
Laser Treatment ◽  
Air Cooling ◽  
Tumescent Anesthesia ◽  
Endovenous Laser Treatment

scholarly journals Safety and efficacy of dronedarone from clinical trials to real-world evidence: implications for its use in atrial fibrillation

EP Europace ◽  
2019 ◽  
Author(s):  
Giuseppe Boriani ◽  
Carina Blomström-Lundqvist ◽  
Stefan H Hohnloser ◽  
Lennart Bergfeldt ◽  
Giovanni L Botto ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Real World ◽  
Liver Toxicity ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Plasma Concentrations ◽  
Low Risk ◽  
Safety Concerns ◽  
Real World Evidence ◽  
Liver Safety

Abstract Efficacy and safety of dronedarone was shown in the ATHENA trial for paroxysmal or persistent atrial fibrillation (AF) patients. Further trials revealed safety concerns in patients with heart failure and permanent AF. This review summarizes insights from recent real-world studies and meta-analyses, including reports on efficacy, with focus on liver safety, mortality risk in patients with paroxysmal/persistent AF, and interactions of dronedarone with direct oral anticoagulants. Reports of rapidly progressing liver failure in dronedarone-prescribed patients in 2011 led to regulatory cautions about potential liver toxicity. Recent real-world evidence suggests dronedarone liver safety profile is similar to other antiarrhythmics and liver toxicity could be equally common with many Class III antiarrhythmics. Dronedarone safety concerns (increased mortality in patients with permanent AF) were raised based on randomized controlled trials (RCT) (ANDROMEDA and PALLAS), but comedication with digoxin may have increased the mortality rates in PALLAS, considering the dronedarone–digoxin pharmacokinetic (PK) interaction. Real-world data on apixaban–dronedarone interactions and edoxaban RCT observations suggest no significant safety risks for these drug combinations. Median trough plasma concentrations of dabigatran 110 mg during concomitant use with dronedarone are at acceptable levels, while PK data on the rivaroxaban–dronedarone interaction are unavailable. In RCTs and real-world studies, dronedarone significantly reduces AF burden and cardiovascular hospitalizations, and demonstrates a low risk for proarrhythmia in patients with paroxysmal or persistent AF. The concerns on liver safety must be balanced against the significant reduction in hospitalizations in patients with non-permanent AF and low risk for proarrhythmias following dronedarone treatment.

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