scholarly journals Oxidative Stress in Type 1 Diabetes Mellitus: Ethnic Aspects

2018 ◽  
Author(s):  
Lyubov I. Kolesnikova ◽  
Marina A. Darenskaya ◽  
Lyudmila A. Grebenkina ◽  
Svetlana V. Gnusina ◽  
Sergey I. Kolesnikov
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus

scholarly journals Oxidative Stress in Patients with Type 1 Diabetes Mellitus: Is It Affected by a Single Bout of Prolonged Exercise?

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99062 ◽  
Author(s):  
Maria Pia Francescato ◽  
Giuliana Stel ◽  
Mario Geat ◽  
Sabina Cauci
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Prolonged Exercise ◽  
Single Bout

Role of asymmetric-dimethyl-l-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus

2009 ◽  
Vol 86 (3) ◽  
pp. 173-176 ◽  
Author(s):  
Dario Pitocco ◽  
Francesco Zaccardi ◽  
Enrico Di Stasio ◽  
Federica Romitelli ◽  
Francesca Martini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Nitrite Nitrate ◽  
Female Subjects

Parameters of oxidative stress in children with Type 1 diabetes mellitus and their relatives

2003 ◽  
Vol 17 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Jana Varvařovská ◽  
Jaroslav Racek ◽  
František Stožický ◽  
Jiřı́ Souček ◽  
Ladislav Trefil ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus

Assessment of biomarkers of inflammation and premature atherosclerosis in adolescents with type-1 diabetes mellitus

2019 ◽  
Vol 32 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Ghufran Babar ◽  
Mark Clements ◽  
Hongying Dai ◽  
Geetha Raghuveer
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Type 1 Diabetes Mellitus ◽  
Pearson Correlation ◽  
Premature Coronary Artery Disease ◽  
The Impact ◽  
Early Atherosclerosis

Abstract Background Type-1 diabetes mellitus (T1DM) causes endothelial dysfunction and early atherosclerosis, which can result in premature coronary artery disease. The aim of this study was to determine the impact of glycemic control, vascular oxidative stress and inflammation on vascular health in adolescents with T1DM. Methods This was a cross-sectional study in adolescents with age- and sex-matched T1DM who were ≥12 years and were at least 2 years post-diagnosis. Recruitment was balanced to include individuals with hemoglobin A1c (HbA1c) ≤8.5% (n=27) or with HbA1c ≥9.5% (n=25). Biomarkers of inflammation were measured in the blood including C-reactive protein (CRP), interleukin-6 (IL-6), intercellular adhesion molecule-1 (ICAM-1), E-selectin, fibrinogen and tumor necrosis factor-α (TNF-α). Carotid intima media thickness (cIMT) and peripheral arterial tonometry (PAT) were assessed. Results Plasma E-selectin level was significantly different between the two groups with higher levels in the group with HbA1c ≥9.5% (65.0±27.7 ng/mL vs. 48.8±21.5 ng/mL, p=0.02). Though cIMT and PAT were not significantly different between the groups, Pearson correlation showed a significant direct relationship between rising HbA1c and mean right cIMT (p=0.02; r=0.37), PAT (p=0.03, r=0.31) and fibrinogen (p=0.03, r=0.03). Conclusions Elevated E-selectin level is an early marker of oxidative stress in T1DM patients with an elevated HbA1c level. Suboptimal glycemic control as evidenced by a rising HbA1c causes early atherosclerosis.

Biomarkers of oxidative stress and antioxidant defense in patients with type 1 diabetes mellitus

2018 ◽  
Vol 10 (6) ◽  
pp. 198
Author(s):  
Nadia Alghazir ◽  
Rabia Alghazeer ◽  
Nuri Awayn ◽  
Obiyda Ahtiwesh ◽  
Sana Elgahmasi
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Antioxidant Defense ◽  
Biomarkers Of Oxidative Stress

Nanoparticles of beetroot plant extract (Beta vulgaris L.) as an alternative therapy for type 1 diabetes mellitus : A review

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2832-2838
Author(s):  
Faizal Achmad Hidayat ◽  
Herwienda Fatmayoni ◽  
Stefani Ayuningtyas ◽  
Anggi Muhtar Pratama
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Free Radicals ◽  
Type 1 Diabetes Mellitus ◽  
Beta Vulgaris ◽  
Alternative Therapy ◽  
Antidiabetic Activity ◽  
The World

Type 1 diabetes mellitus is one of the most common degenerative diseases in the world. Out of 463 million diabetes mellitus patients in the world, 10% of them are type 1 diabetes mellitus patients. One of the complication causes and severity of type 1 diabetes mellitus is oxidative stress. Oxidative stress occurs due to the build-up of excess free radicals obtained from the metabolism of glucose and lipids. Free radicals that cause oxidative stress can be minimized with antioxidants. Beetroot (Beta vulgaris L.) is a plant that is rich in antioxidants and can be used as an alternative therapy for type 1 diabetes mellitus. Various flavonoid contents in beetroot extracts include quercetin, rutin, apigenin, kaempferol, and ferulic acid compounds that have antioxidant and antidiabetic activity. With the evolve of nanoparticle technology, it can be used to increase the solubility of drugs in water, to increase the duration of the drug in the systemic circulation, and to make drug release occurs gradually. The properties of this nanoparticle extract are indispensable for the efficacy and efficiency of treatment. The results of this study provide a lot of information and innovation for the development of the use of beetroot and the treatment of type 1 diabetes mellitus.

scholarly journals Oxidative Stress and Cardiovascular Risk in Type 1 Diabetes Mellitus: Insights From the DCCT/EDIC Study

2018 ◽  
Vol 7 (10) ◽  
Author(s):  
W.H. Wilson Tang ◽  
Paula McGee ◽  
John M. Lachin ◽  
Daniel Y. Li ◽  
Byron Hoogwerf ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Cardiovascular Risk ◽  
Type 1 Diabetes Mellitus

The role of carbohydrate counting in glycemic control and oxidative stress in patients with type 1 diabetes mellitus (T1DM)

HORMONES ◽  
2020 ◽  
Vol 19 (3) ◽  
pp. 433-438
Author(s):  
Eirini Kostopoulou ◽  
Ioulia Livada ◽  
Ioanna Partsalaki ◽  
Fotini Lamari ◽  
Spyros Skiadopoulos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Type 1 Diabetes Mellitus ◽  
Carbohydrate Counting ◽  
And Oxidative Stress
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