scholarly journals Update on Bone Grafting Materials Used in Dentistry in the Bone Healing Process: Our Experience from Translational Studies to Their Clinical Use

Author(s):  
Gretel G. Pellegrini ◽  
Andrea S. Mattiuzzi ◽  
Miguel A. Pellegrini ◽  
Luis A. Corso ◽  
Cintya P. Contreras Morales ◽  
...  

2017 ◽  
Vol 18 (1) ◽  
pp. 19-32 ◽  
Author(s):  
Giovanna Iezzi ◽  
Adriano Piattelli ◽  
Alessandra Giuliani ◽  
Carlo Mangano ◽  
Licia Manzon ◽  
...  


2015 ◽  
Vol 86 (4) ◽  
pp. 578-587 ◽  
Author(s):  
Richard J. Miron ◽  
Dieter D. Bosshardt ◽  
Daniel Buser ◽  
Yufeng Zhang ◽  
Stefano Tugulu ◽  
...  


2012 ◽  
Vol 92 (3) ◽  
pp. 296-306 ◽  
Author(s):  
Hidetsugu Tsujigiwa ◽  
Yasuhisa Hirata ◽  
Naoki Katase ◽  
Rosario Rivera Buery ◽  
Ryo Tamamura ◽  
...  




2019 ◽  
Vol 55 (1) ◽  
pp. 26-32 ◽  
Author(s):  
S. Titsinides ◽  
G. Agrogiannis ◽  
T. Karatzas


2019 ◽  
Vol 14 (1) ◽  
pp. 311-317
Author(s):  
Wei Liu ◽  
Ben Chen ◽  
Youyang Zheng ◽  
Yuehua Shi ◽  
Zhuojin Shi

AbstractPlatelet-rich plasma (PRP) has been shown to be a beneficial growth factor for bone tissue healing and is used in implantology. The aim of this study was to investigate the effects of PRP on bone defects in rabbits. Twenty rabbits were used to establish the implant bone defect model in this study. An intrabony defect (5mm × 5mm × 3mm) was created in alveolar bone in the lower jar of each rabbit. The wound was treated with PRP. The expression of platelet-derived growth factor BB (PDGFBB) was assessed by enzyme-linked immunosorbent assay (ELISA). Focal adhesion kinase (FAK) and related phosphatidylinositol 3-kinase (PI3K)/AKT (protein kinase B) levels were measured by Western blot. The results show that PRP could significantly improve the bone healing process when compared with control, and 10% PRP could markedly increase fibroblast proliferation 48-h post treatment. PDGFBB was higher in the PRP group than that in the control group. PRP treatment also could elevate the phosphorylation of FAK and PI3K/AKT, although the inhibitor of PDGFR could reverse this trend. These results suggest that PRP treatment improves the bone healing process through the FAK/PI3K/AKT pathway.



2021 ◽  
Vol 65 (1) ◽  
pp. 167-195
Author(s):  
Nabil Moussa ◽  
Yijiao Fan ◽  
Harry Dym


2007 ◽  
Vol 21 (4) ◽  
pp. 491-495 ◽  
Author(s):  
S. Pagnutti ◽  
S. Maggi ◽  
D. A. Di Stefano ◽  
M. Ludovichetti


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