scholarly journals Effects of Dehydroepiandrosterone (DHEA) Supplementation to Improve Ovarian Response and IVF Outcomes on Women with Poor Ovarian Response

2018 ◽  
Author(s):  
José Fernando de Macedo ◽  
Maristela Rodrigues Oliveira ◽  
Olga Goiana Martins
Keyword(s):  
Ovarian Response ◽  
Poor Ovarian Response ◽  
Ivf Outcomes

scholarly journals IVF Outcomes of Microdose Flare-up, GnRH Antagonist and Long Protocols in Patients Having a Poor Ovarian Response in the First Treatment Cycle

2021 ◽  
Vol 02 (01) ◽  
Author(s):  
Hassan Mumtaz ◽  
Shahzaib Ahmad ◽  
Farrukh Zaman ◽  
Aamir Ghazanfar
Keyword(s):  
Gnrh Antagonist ◽  
Treatment Cycle ◽  
Ovarian Response ◽  
Poor Ovarian Response ◽  
Ivf Outcomes

scholarly journals OVARIAN RESERVE PARAMETERS AND IVF OUTCOMES IN 510 WOMEN WITH POOR OVARIAN RESPONSE (POR) TREATED WITH INTRAOVARIAN INJECTION OF AUTOLOGOUS PLATELET RICH PLASMA (PRP)

2020 ◽  
Vol 114 (3) ◽  
pp. e458
Author(s):  
Yigit Cakiroglu ◽  
Ayse Saltik ◽  
Aysen Yuceturk ◽  
Ozge Karaosmanoglu ◽  
Sule Yildirim Kopuk ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Platelet Rich Plasma ◽  
Ovarian Response ◽  
Poor Ovarian Response ◽  
Ivf Outcomes ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

scholarly journals Growth hormone alleviates oxidative stress and improves IVF outcomes in Chinese women with poor ovarian response: A randomized controlled trial

2020 ◽  
Author(s):  
Yan Gong ◽  
Kun Zhang ◽  
Dongsheng Xiong ◽  
Jiajing Wei ◽  
Hao Tan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Growth Hormone ◽  
Reactive Oxygen ◽  
Ovarian Response ◽  
Stress Index ◽  
Oxygen Species ◽  
Poor Ovarian Response ◽  
Ivf Outcomes ◽  
Ivf Et

Abstract Background Oxidative stress (OS), defined as an imbalance between reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) excessive production and antioxidant insufficient, has been suggested to be involved in the pathogenesis of poor ovarian response (POR). Growth hormone (GH) can function reduce OS in some types of cells. This study investigated whether GH can significantly improve OS and in vitro fertilization and embryo transfer (IVF-ET) outcomes in patients with POR.Methods This study enrolled 105 and 58 patients with and without POR (controls), respectively, diagnosed according to the Bologna criteria, who underwent conventional IVF-ET. Patients with POR were randomly assigned to two groups: POR-GH group: pretreatment with GH 4IU/d on day 2 of the previous menstrual cycle before IVF till the trigger day; POR-C group: no pretreatment. The markers of OS in follicle fluid (FF),reactive oxygen species (ROS) levels in granulosa cells (GC), and IVF outcomes of the patients were compared between the three groups.Result(s) The endometrial thickness on trigger day, number of cleaved embryos, higher quality embryos, the rates of implantation and clinical pregnancy were significantly increased in POR-GH group compared with POR-C group (P<0.05). Moreover, the FF malondialdehyde (MDA), total oxidant status (TOS), oxidative stress index (OSI) and ROS levels in GC were significantly higher,whereas superoxide dismutase (SOD) and total antioxidant capacity (TAC) were significantly lower in POR-C group compared with non-POR group (P<0.05). Furthermore, the FF TAC was significantly increased, whereas TOS, OSI and intracellular ROS levels were significantly reduced in POR-GH group compared with POR-C group (P<0.05).Conclusion(s) Pretreatment with GH alleviated OS and improved oocyte quality and IVF outcomes in patients with POR.Clinical Trial Registration: Chinese Clinical Trial Registry. ChiCTR1900021269. Registered 8 February 2019, http://www.chictr.org.cn/edit.aspx?pid=35837&htm=4.

scholarly journals IVF OUTCOMES IN 510 WOMEN WITH POOR OVARIAN RESPONSE (POR) TREATED WITH INTRAOVARIAN INJECTION OF AUTOLOGOUS PLATELET RICH PLASMA (PRP)

2021 ◽  
Vol 116 (3) ◽  
pp. e28-e29
Author(s):  
Yigit Cakiroglu ◽  
Aysen Yuceturk ◽  
Ozge Karaosmanoglu ◽  
Sule Yildirim Kopuk ◽  
Zeynep Ece Utkan Korun ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Ovarian Response ◽  
Poor Ovarian Response ◽  
Ivf Outcomes ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

Risk factors of poor ovarian response in IVF practice

GYNECOLOGY ◽  
2014 ◽  
Vol 16 (5) ◽  
pp. 73-77
Author(s):  
R.E. Vanyan ◽  
◽  
N.V. Dolgushina ◽  
Keyword(s):  
Risk Factors ◽  
Ovarian Response ◽  
Poor Ovarian Response

scholarly journals A flexible short protocol in women with poor ovarian response over 40 years old

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Xinyue Zhang ◽  
Ting Feng ◽  
Jihong Yang ◽  
Yingying Hao ◽  
Suying Li ◽  
...  
Keyword(s):  
Embryo Implantation ◽  
Ovarian Response ◽  
Oocyte Quality ◽  
Poor Ovarian Response ◽  
Stimulation Protocol ◽  
Start Time ◽  
Ovulation Stimulation ◽  
Mild Stimulation ◽  
Successful Clinical Outcome ◽  
Over 40 Years

Abstract Background Ovarian responsiveness to controlled ovarian stimulation is essential for a successful clinical outcome in assisted reproductive technology (ART) cycles. We aimed to find a suitable new ovulation stimulation protocol for poor ovarian response (POR) patients over 40 years old. Methods A retrospective analysis of 488 ART cycles was evaluated from January 2015 to June 2019. Comparisons were made between the flexible short protocol (FSP), routine short protocol and mild stimulation protocol. Results Compared with the routine short protocol, the FSP delayed the gonadotropin start time and reduced the total gonadotropin dose per stimulation cycle. At the same time, compared with the mild stimulation protocol, the FSP improved oocyte quality and embryo quality and improved embryo implantation potential after transfer. Furthermore, the use of the FSP reduced the probability of premature ovulation, as it inhibited the premature luteinizing hormone (LH) surge to a certain extent. Conclusions The FSP yielded better outcomes than other protocols for patients with POR over 40 years old in our study. However, further prospective studies are needed to provide more substantial evidence and to determine whether the FSP can be successful for both patients over 40 years group and younger POR patients.

Sign in / Sign up

Export Citation Format

Share Document