scholarly journals Inorganic Polyphosphates Are Important for Cell Survival and Motility of Human Skin Keratinocytes and Play a Role in Wound Healing

2020 ◽  
Author(s):  
Cynthia M. Simbulan-Rosenthal ◽  
Bonnie C. Carney ◽  
Anirudh Gaur ◽  
Manish Moghe ◽  
Elliott Crooke ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cell Survival ◽  
Human Skin ◽  
Inorganic Polyphosphates ◽  
Skin Keratinocytes

Inorganic polyphosphates are important for cell survival and motility of human skin keratinocytes

2015 ◽  
Vol 24 (8) ◽  
pp. 636-639 ◽  
Author(s):  
Cynthia M. Simbulan-Rosenthal ◽  
Anirudh Gaur ◽  
Virginia A. Sanabria ◽  
Lucia J. Dussan ◽  
Rahul Saxena ◽  
...  
Keyword(s):  
Cell Survival ◽  
Human Skin ◽  
Inorganic Polyphosphates ◽  
Skin Keratinocytes

Positive Promoting Effects of Smilax China Flower Absolute on the Wound Healing/Skin Barrier Repair‐Related Responses of HaCaT Human Skin Keratinocytes

2021 ◽  
Author(s):  
Yali Li ◽  
Kyung Jong Won ◽  
Do Yoon Kim ◽  
Ha Bin Kim ◽  
Hye Min Kang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Skin Barrier ◽  
Skin Keratinocytes ◽  
Barrier Repair ◽  
Skin Barrier Repair

scholarly journals Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction

2021 ◽  
Vol 22 (11) ◽  
pp. 5474
Author(s):  
Shun Kimura ◽  
Takashi Tsuji
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Human Skin ◽  
Developmental Stages ◽  
Control Mechanisms ◽  
Tissue Remodelling ◽  
Skin Equivalents ◽  
Immunological Interactions ◽  
Stress Signals ◽  
Specific Species

In the past decade, a new frontier in scarless wound healing has arisen because of significant advances in the field of wound healing realised by incorporating emerging concepts from mechanobiology and immunology. The complete integumentary organ system (IOS) regeneration and scarless wound healing mechanism, which occurs in specific species, body sites and developmental stages, clearly shows that mechanical stress signals and immune responses play important roles in determining the wound healing mode. Advances in tissue engineering technology have led to the production of novel human skin equivalents and organoids that reproduce cell–cell interactions with tissue-scale tensional homeostasis, and enable us to evaluate skin tissue morphology, functionality, drug response and wound healing. This breakthrough in tissue engineering has the potential to accelerate the understanding of wound healing control mechanisms through complex mechanobiological and immunological interactions. In this review, we present an overview of recent studies of biomechanical and immunological wound healing and tissue remodelling mechanisms through comparisons of species- and developmental stage-dependent wound healing mechanisms. We also discuss the possibility of elucidating the control mechanism of wound healing involving mechanobiological and immunological interaction by using next-generation human skin equivalents.

Development of a Three-Dimensional Human Skin Equivalent Wound Model for Investigating Novel Wound Healing Therapies

2010 ◽  
Vol 16 (5) ◽  
pp. 1111-1123 ◽  
Author(s):  
Yan Xie ◽  
Simone C. Rizzi ◽  
Rebecca Dawson ◽  
Emily Lynam ◽  
Sean Richards ◽  
...  
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Three Dimensional ◽  
Skin Equivalent ◽  
Wound Model ◽  
Human Skin Equivalent

scholarly journals Protein C Is an Autocrine Growth Factor for Human Skin Keratinocytes

2007 ◽  
Vol 282 (18) ◽  
pp. 13610-13616 ◽  
Author(s):  
Meilang Xue ◽  
David Campbell ◽  
Christopher J. Jackson
Keyword(s):  
Growth Factor ◽  
Human Skin ◽  
Protein C ◽  
Autocrine Growth ◽  
Autocrine Growth Factor ◽  
Skin Keratinocytes

Tissue-Engineered Human Skin Equivalents and Their Applications in Wound Healing

2017 ◽  
pp. 215-241
Author(s):  
Lara Yildirimer ◽  
Divia Hobson ◽  
Zhi Yuan William Lin ◽  
Wenguo Cui ◽  
Xin Zhao
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Skin Equivalents
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