scholarly journals Fluorogenic Polyfunctional Coumarin-Based Chemosensors for Multianalyte Detection

2020 ◽  
Author(s):  
Alexander Dubonosov ◽  
Vladimir Bren
Keyword(s):  
Multianalyte Detection

Simultaneous Multianalyte Detection with a Nanometer-Scale Pore

2001 ◽  
Vol 73 (10) ◽  
pp. 2268-2272 ◽  
Author(s):  
John J. Kasianowicz ◽  
Sarah E. Henrickson ◽  
Howard H. Weetall ◽  
Baldwin Robertson
Keyword(s):  
Nanometer Scale ◽  
Multianalyte Detection

Surface-plasmon-resonance-based array biosensors for multianalyte detection

1998 ◽  
Author(s):  
Michael J. O'Brien II ◽  
Victor H. Perez-Luna ◽  
Leonard M. Tender ◽  
Mark Edmunds ◽  
Ben Lascelles ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Multianalyte Detection

scholarly journals Silicon-based Biosensors for Rapid Detection of Protein or Nucleic Acid Targets

2001 ◽  
Vol 47 (10) ◽  
pp. 1894-1900 ◽  
Author(s):  
Robert Jenison ◽  
Helen La ◽  
Ayla Haeberli ◽  
Rachel Ostroff ◽  
Barry Polisky
Keyword(s):  
Thin Film ◽  
Nucleic Acid ◽  
Interferon Γ ◽  
Wild Type ◽  
Signal To Noise ◽  
Cytokine Detection ◽  
Apparent Color ◽  
Multianalyte Detection ◽  
A Charge ◽  
Silicon Based

Abstract Background: We developed a silicon-based biosensor that generates visual, qualitative results or quantitative results for the detection of protein or nucleic acid targets in a multiplex format. Methods: Capture probes were immobilized either passively or covalently on the optically coated surface of the biosensor. Intermolecular interactions of the immobilized capture probe with specific target molecules were transduced into a molecular thin film. Thin films were generated by enzyme-catalyzed deposition in the vicinity of the surface-bound target. The increased thickness on the surface changed the apparent color of the biosensor by altering the interference pattern of reflected light. Results: Cytokine detection was achieved in a 40-min multiplex assay. Detection limits were 4 ng/L for interleukin (IL)-6, 31 ng/L for IL1-β, and 437 ng/L for interferon-γ. In multianalyte experiments, cytokines were specifically detected with signal-to-noise ratios ranging from 15 to 80. With a modified optical surface, specificity was also demonstrated in a nucleic acid array with unambiguous discrimination of single-base changes in a 15-min assay. For homozygous wild-type and homozygous mutant samples, signal-to-noise ratios of ∼100 were observed. Heterozygous samples yielded approximately equivalent signals for wild-type and mutant capture probes. Conclusions: The thin-film biosensor allows rapid, sensitive, and specific detection of protein or nucleic acid targets in an array format with results read visually or quantified with a charge-coupled device camera. This biosensor is suited for multianalyte detection in clinical diagnostic assays.

Optical PMMA chip for multianalyte detection

2007 ◽  
Author(s):  
F. Baldini ◽  
A. Carloni ◽  
R. Falciai ◽  
A. Giannetti ◽  
A. Mencaglia ◽  
...  
Keyword(s):  
Multianalyte Detection

scholarly journals Electric field induced surface-enhanced Raman spectroscopy for multianalyte detection

2015 ◽  
Vol 17 (11) ◽  
pp. 7095-7099 ◽  
Author(s):  
Sumeet Walia ◽  
Aditya K. Shah ◽  
Paul R. Stoddart ◽  
Madhu Bhaskaran ◽  
Sharath Sriram
Keyword(s):  
Raman Spectroscopy ◽  
Electric Field ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Multianalyte Detection ◽  
Sers Sensing

This work demonstrates the ability to detect and isolate an analyte from a multianalyte mixture by SERS sensing.

Thermally Stable Plasmonic Nanocermets Grown on Microengineered Surfaces as Versatile Surface Enhanced Raman Spectroscopy Sensors for Multianalyte Detection

2014 ◽  
Vol 6 (24) ◽  
pp. 22733-22742 ◽  
Author(s):  
Nitant Gupta ◽  
Disha Gupta ◽  
Shantanu Aggarwal ◽  
Soumik Siddhanta ◽  
Chandrabhas Narayana ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Thermally Stable ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Multianalyte Detection

External cavity widely tunable quantum cascade laser based hollow waveguide gas sensors for multianalyte detection

2009 ◽  
Vol 140 (1) ◽  
pp. 24-28 ◽  
Author(s):  
C. Young ◽  
S.-S. Kim ◽  
Y. Luzinova ◽  
M. Weida ◽  
D. Arnone ◽  
...  
Keyword(s):  
Quantum Cascade Laser ◽  
Gas Sensors ◽  
External Cavity ◽  
Hollow Waveguide ◽  
Quantum Cascade ◽  
Multianalyte Detection

Facilitated Transfer of Hydrophilic Anions across the Nitrobenzene–Water Interface by a Hydrogen-Bonding Ionophore: Applicability for Multianalyte Detection

2001 ◽  
Vol 30 (10) ◽  
pp. 1058-1059 ◽  
Author(s):  
Seiichi Nishizawa ◽  
Tomoyuki Yokobori ◽  
Takeshi Shioya ◽  
Norio Teramae
Keyword(s):  
Hydrogen Bonding ◽  
Water Interface ◽  
Multianalyte Detection

Optical PMMA Chip Suitable for Multianalyte Detection

2008 ◽  
Vol 8 (7) ◽  
pp. 1305-1309 ◽  
Author(s):  
Francesco Baldini ◽  
Adolfo Carloni ◽  
Ambra Giannetti ◽  
Andrea Mencaglia ◽  
Giampiero Porro ◽  
...  
Keyword(s):  
Multianalyte Detection
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