Biological Application and Disease of Oxidoreductase Enzymes

Although scanning electron microscopy has a great potential in biological application, there are certain limitations in visualization of the biological structure. Satisfactory techniques to demonstrate natural surfaces of the tissue and the cell have been reported by several investigators. However, it is commonly found that the surface cell membrane is covered with a minute amount of mucin, secretory substance or tissue fluid as physiological, pathological or artefactual condition. These substances give a false surface appearance, especially when the tissue is fixed with strong fixatives. It seems important to remove these coating substances from the surface of the cell for demonstration of the true structure.

A Peptoid with Extended Shape in Water

10.26434/chemrxiv.7552139 ◽

2019 ◽

Author(s):

Jumpei Morimoto ◽

Yasuhiro Fukuda ◽

Takumu Watanabe ◽

Daisuke Kuroda ◽

Kouhei Tsumoto ◽

...

Keyword(s):

Spectroscopic Analysis ◽

Dimensional Space ◽

Three Dimensional ◽

Biomolecular Recognition ◽

Biological Application ◽

New Class ◽

Proteolytic Resistance ◽

Pharmacokinetic Properties ◽

Optically Pure ◽

Three Dimensional Space

<div> <div> <div> <p>“Peptoids” was proposed, over decades ago, as a term describing analogs of peptides that exhibit better physicochemical and pharmacokinetic properties than peptides. Oligo-(N-substituted glycines) (oligo-NSG) was previously proposed as a peptoid due to its high proteolytic resistance and membrane permeability. However, oligo-NSG is conformationally flexible and is difficult to achieve a defined shape in water. This conformational flexibility is severely limiting biological application of oligo-NSG. Here, we propose oligo-(N-substituted alanines) (oligo-NSA) as a new peptoid that forms a defined shape in water. A synthetic method established in this study enabled the first isolation and conformational study of optically pure oligo-NSA. Computational simulations, crystallographic studies and spectroscopic analysis demonstrated the well-defined extended shape of oligo-NSA realized by backbone steric effects. The new class of peptoid achieves the constrained conformation without any assistance of N-substituents and serves as an ideal scaffold for displaying functional groups in well-defined three-dimensional space, which leads to effective biomolecular recognition. </p> </div> </div> </div>

Non-biological application of DNA molecules

Biomics ◽

10.31301/2221-6197.bmcs.2019-28 ◽

2019 ◽

Vol 11 (3) ◽

pp. 344-377

Author(s):

A.R. Sakhabutdinova ◽

K.I. Mikhailenko ◽

R.R. Garafutdinov ◽

O.Yu. Kiryanova ◽

M.A. Sagitova ◽

...

Keyword(s):

Biological Application ◽

Dna Molecules

Medicinal and Biological Significance of Phenoxazine Derivatives

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557520666201214102151 ◽

2020 ◽

Vol 20 ◽

Author(s):

Jaya Dwivedi ◽

Neetu Yaduvanshi ◽

Shruti Shukla ◽

Sonika Jain

Keyword(s):

Drug Resistance ◽

Biological Significance ◽

Biological Application ◽

Pharmacological Activities ◽

Resistance Reversal ◽

Anti Inflammatory ◽

Pharmacological Application

: Since 1887, phenoxazine derivatives have attracted attention of chemist due to its versatile utility, industrially and pharmacologically. Literature is found abundant with various pharmacological activities of phenoxazine derivatives like antitumor, anticancer, antifungal, antibacterial, anti-inflammatory, anti-diabetic, anti-viral, anti-malarial, antidepressant, analgesic and many other drug resistance reversal activities. This review covers detailed over-view on pharmacological application of phenoxazine nucleus, its chemistry and reactivity and also illustrating the incorporation of different group at different positions enhancing its biological application, besides some synthetic procedures.

A Fluidic Motherboard for Multiplexed Simultaneous and Modular Detection in Microfluidic Systems for Biological Application

Micro and Nanosystems ◽

10.2174/1876402911002040227 ◽

2010 ◽

Vol 2 (4) ◽

pp. 227-238 ◽

Cited By ~ 15

Author(s):

Gerardo Perozziello ◽

Giuseppina Simone ◽

Patrizio Candeloro ◽

Francesco Gentile ◽

Natalia Malara ◽

...

Keyword(s):

Biological Application ◽

Microfluidic Systems

Brief introduction of keratin and its biological application, especially in drug delivery

Emergent Materials ◽

10.1007/s42247-021-00216-3 ◽

2021 ◽

Author(s):

Huifang Zhang ◽

Feng Su ◽

Xiaofang Ma ◽

Guohu Zhao

Keyword(s):

Drug Delivery ◽

Biological Application

Fluorescent quantum dots: An insight on synthesis and potential biological application as drug carrier in cancer

Biochemistry and Biophysics Reports ◽

10.1016/j.bbrep.2021.100962 ◽

2021 ◽

Vol 26 ◽

pp. 100962

Author(s):

P. Tandale ◽

Neeraj Choudhary ◽

Joga Singh ◽

Akanksha Sharma ◽

Ananya Shukla ◽

...

Keyword(s):

Quantum Dots ◽

Drug Carrier ◽

Biological Application

Highly selective and sensitive benzo-imidazo-pyrrolo[3,4-c] pyridines based chemosensor for iron, DFT calculation and its biological application

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.130280 ◽

2021 ◽

Vol 1236 ◽

pp. 130280

Author(s):

Pampa Maity ◽

Barnali Naskar ◽

Chitrangada Das Mukhopadhyay ◽

Sanchita Goswami ◽

Chhanda Mukhopadhyay

Keyword(s):

Dft Calculation ◽

Biological Application

Vitamin E-loaded bigels and emulsions: Physicochemical characterization and potential biological application

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2021.111651 ◽

2021 ◽

Vol 201 ◽

pp. 111651

Author(s):

Renata Miliani Martinez ◽

Wagner Vidal Magalhães ◽

Bianca da Silva Sufi ◽

Giovana Padovani ◽

Lucas Idacir Sbrugnera Nazato ◽

...

Keyword(s):

Vitamin E ◽

Physicochemical Characterization ◽

Biological Application

A tetraphenylethylene (TPE)-based supra-amphiphilic organoplatinum(ii) metallacycle and its self-assembly behaviour

Materials Chemistry Frontiers ◽

10.1039/c7qm00107j ◽

2017 ◽

Vol 1 (9) ◽

pp. 1823-1828 ◽

Cited By ~ 46

Author(s):

Wei Zheng ◽

Guang Yang ◽

Shu-Ting Jiang ◽

Nannan Shao ◽

Guang-Qiang Yin ◽

...

Keyword(s):

Self Assembly ◽

Cell Imaging ◽

Biological Application

A tetraphenylethylene (TPE)-based supra-amphiphilic organoplatinum(ii) metallacycle was successfully prepared, which presented biological application in cell imaging.