scholarly journals Neuromuscular Effects and Rehabilitation in Guillain-Barré Syndrome Associated with Zika Virus Infection

2020 ◽  
Author(s):  
Thomas Harbo ◽  
Henning Andersen
Keyword(s):  
Zika Virus ◽  
Neuromuscular Electrical Stimulation ◽  
Guillain Barre Syndrome ◽  
Current Evidence ◽  
Guillain Barré Syndrome ◽  
Mild Impairment ◽  
Guillain Barré ◽  
Denervated Muscles ◽  
Evidence Based Guidelines

The 2015–2017 Zika Virus outbreak caused a high increase in patients with Guillain-Barré syndrome (GBS), a post infectious autoimmune disease of the peripheral nerves. The severity of GBS can range from mild impairment with fast recovery to complete paralysis including severe respiratory or autonomic failure. Recovery may take months and even years and may be incomplete despite disease modifying treatment with IVIG or plasma exchange. Therefore, optimal supportive care and effective rehabilitation remain crucial. Multidisciplinary rehabilitation is recommended but may be challenging in the acute phase because of limited patient participation due to profound muscle weakness and severe pain. Inactive denervated muscles will inevitably undergo rapid degeneration resulting in wasting, weakness, and contractures as major long-term complications in severely affected patients. In this chapter, the current evidence of rehabilitation on the short- and long-term motor function in GBS is reviewed, including newly obtained experiences with neuromuscular electrical stimulation (NMES). Rehabilitation remains an area lacking well designed and controlled clinical studies and thus a clear lack of evidence-based guidelines.

scholarly journals Long-term outcomes of Guillain-Barré syndrome possibly associated with Zika virus infection

PLoS ONE ◽  
2019 ◽  
Vol 14 (8) ◽  
pp. e0220049 ◽  
Author(s):  
Diana M. Walteros ◽  
Jesus Soares ◽  
Ashley R. Styczynski ◽  
Joseph Y. Abrams ◽  
Jose I. Galindo-Buitrago ◽  
...  
Keyword(s):  
Virus Infection ◽  
Zika Virus ◽  
Guillain Barre Syndrome ◽  
Long Term Outcomes ◽  
Zika Virus Infection ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Long-term impact on work and private life after Guillain–Barré syndrome

2002 ◽  
Vol 201 (1-2) ◽  
pp. 13-17 ◽  
Author(s):  
Robert A.J.A.M Bernsen ◽  
Aeiko E.J de Jager ◽  
Paul I.M Schmitz ◽  
Frans G.A van der Meché
Keyword(s):  
Private Life ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Long Term Impact

scholarly journals Zika Virus and the Guillain–Barré Syndrome — Case Series from Seven Countries

2016 ◽  
Vol 375 (16) ◽  
pp. 1598-1601 ◽  
Author(s):  
Thais dos Santos ◽  
Angel Rodriguez ◽  
Maria Almiron ◽  
Antonio Sanhueza ◽  
Pilar Ramon ◽  
...  
Keyword(s):  
Zika Virus ◽  
Case Series ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review

PLoS Medicine ◽  
2017 ◽  
Vol 14 (1) ◽  
pp. e1002203 ◽  
Author(s):  
Fabienne Krauer ◽  
Maurane Riesen ◽  
Ludovic Reveiz ◽  
Olufemi T. Oladapo ◽  
Ruth Martínez-Vega ◽  
...  
Keyword(s):  
Systematic Review ◽  
Virus Infection ◽  
Zika Virus ◽  
Guillain Barre Syndrome ◽  
Brain Abnormalities ◽  
Zika Virus Infection ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals A Case Report of a Patient with Guillain-Barre Syndrome Who Complained of Quadriplegia

2021 ◽  
Vol 42 (5) ◽  
pp. 1009-1019
Author(s):  
Gi-yoon Heo ◽  
Chan Lee ◽  
Im-hak Cho ◽  
Hee-kyung Kang ◽  
Min-hwa Kim ◽  
...  
Keyword(s):  
Muscle Weakness ◽  
Muscle Function ◽  
Hospital Admissions ◽  
Combined Treatment ◽  
Gait Pattern ◽  
Guillain Barre Syndrome ◽  
Poor Prognostic Factor ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Purpose: The aim of this study was to report the improvement of Guillain-Barre syndrome after long-term combination treatment with Korean medicine.Methods: A patient was diagnosed with Guillain-Barre syndrome and treated with herbal medicine, acupuncture, pharmacopuncture, moxibustion, and exercise, including quadruped walking after three hospital admissions. To evaluate muscle strength and weakness, we measured manual muscle function, gait pattern, and the speed of quadruped walking.Results: The patient's muscle weakness in the extremities and gait stance were improved. The speed of quadruped walking was increased.Conclusion: We consider that combined treatment with Korean medicine might be effective for the muscle weakness of Guillain-Barre syndrome with a poor prognostic factor. To verify the effectiveness of this treatment, further research is needed.

scholarly journals The re-emergence of Zika in Brazil in 2020: a case of Guillain Barré Syndrome during the low season for arboviral infections

2020 ◽  
Vol 27 (7) ◽  
Author(s):  
Kevan M Akrami ◽  
Betania Mara Freitas de Nogueira ◽  
Mateus Santana do Rosário ◽  
Laise de Moraes ◽  
Marli Tenório Cordeiro ◽  
...  
Keyword(s):  
Zika Virus ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Zika virus cases in Brazil have diminished since emergence in 2015. We report Guillain Barré Syndrome caused by Zika and possible Chikungunya co-infection during an expected low arboviral season. This case highlights the importance of clinical vigilance for Zika in those with neurological syndromes outside typical arboviral season.

scholarly journals Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 196 ◽  
Author(s):  
Michel Jacques Counotte ◽  
Dianne Egli-Gany ◽  
Maurane Riesen ◽  
Million Abraha ◽  
Teegwendé Valérie Porgo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Zika Virus ◽  
Congenital Abnormalities ◽  
Causal Link ◽  
The Body ◽  
Guillain Barre Syndrome ◽  
Sufficient Evidence ◽  
Zikv Infection ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Background. The Zika virus (ZIKV) outbreak in the Americas has caused international concern due to neurological sequelae linked to the infection, such as microcephaly and Guillain-Barré syndrome (GBS). The World Health Organization stated that there is “sufficient evidence to conclude that Zika virus is a cause of congenital abnormalities and is a trigger of GBS”. This conclusion was based on a systematic review of the evidence published until 30.05.2016. Since then, the body of evidence has grown substantially, leading to this update of that systematic review with new evidence published from 30.05.2016 – 18.01.2017, update 1. Methods. We review evidence on the causal link between ZIKV infection and adverse congenital outcomes and the causal link between ZIKV infection and GBS or immune-mediated thrombocytopaenia purpura. We also describe the transition of the review into a living systematic review, a review that is continually updated. Results. Between 30.05.2016 and 18.01.2017, we identified 2413 publications, of which 101 publications were included. The evidence added in this update confirms the conclusion of a causal association between ZIKV and adverse congenital outcomes. New findings expand the evidence base in the dimensions of biological plausibility, strength of association, animal experiments and specificity. For GBS, the body of evidence has grown during the search period for update 1, but only for dimensions that were already populated in the previous version. There is still a limited understanding of the biological pathways that potentially cause the occurrence of autoimmune disease following ZIKV infection. Conclusions. This systematic review confirms previous conclusions that ZIKV is a cause of congenital abnormalities, including microcephaly, and is a trigger of GBS. The transition to living systematic review techniques and methodology provides a proof of concept for the use of these methods to synthesise evidence about an emerging pathogen such as ZIKV.

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