scholarly journals Celiac Disease

2021 ◽  
Author(s):  
Nour Amin Elsahoryi
Keyword(s):  
Celiac Disease ◽  
Effective Treatment ◽  
Diagnostic Methods ◽  
Gluten Free Diet ◽  
Comprehensive Overview ◽  
Disease Epidemiology ◽  
Complete Exclusion ◽  
Alternative Diet ◽  
The Individual

Celiac disease is chronic autoimmune-mediated small intestinal enteropathy. CD caused by ingestion of the dietary gluten that found in wheat, barley, and rye, in the individual who are predisposed genetically by having leucocyte antigen, (HLA)-DQ2 or -DQ8-positive. Rigorous adherence to a gluten-free diet is the only treatment for this condition to reduce the symptoms and the consequences at the short-term and the long term. The aim of this chapter is provide updates and comprehensive overview about the celiac disease epidemiology, pathogenetic information, clinical, and diagnostic methods, updated therapeutic strategy approaches that followed as a treatment and recommendations. Its challenge to understand all the domains that causes celiac disease. Finding alternative diet and trying different lifestyle still under debates. However, complete exclusion of the gluten-containing food from the patient’s diet is the only effective treatment to avoid the disease complications.

scholarly journals Rationale for Timing of Follow-Up Visits to Assess Gluten-Free Diet in Celiac Disease Patients Based on Data Mining

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 357
Author(s):  
Alfonso Rodríguez-Herrera ◽  
Joaquín Reyes-Andrade ◽  
Cristina Rubio-Escudero
Keyword(s):  
Data Mining ◽  
Celiac Disease ◽  
Cultural Context ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Adherence To Diet ◽  
And Gender ◽  
Few Data

The assessment of compliance of gluten-free diet (GFD) is a keystone in the supervision of celiac disease (CD) patients. Few data are available documenting evidence-based follow-up frequency for CD patients. In this work we aim at creating a criterion for timing of clinical follow-up for CD patients using data mining. We have applied data mining to a dataset with 188 CD patients on GFD (75% of them are children below 14 years old), evaluating the presence of gluten immunogenic peptides (GIP) in stools as an adherence to diet marker. The variables considered are gender, age, years following GFD and adherence to the GFD by fecal GIP. The results identify patients on GFD for more than two years (41.5% of the patients) as more prone to poor compliance and so needing more frequent follow-up than patients with less than 2 years on GFD. This is against the usual clinical practice of following less patients on long term GFD, as they are supposed to perform better. Our results support different timing follow-up frequency taking into consideration the number of years on GFD, age and gender. Patients on long term GFD should have a more frequent monitoring as they show a higher level of gluten exposure. A gender perspective should also be considered as non-compliance is partially linked to gender in our results: Males tend to get more gluten exposure, at least in the cultural context where our study was carried out. Children tend to perform better than teenagers or adults.

A Phase I Study to Determine Safety, Tolerability and Bioactivity of Nexvax2® in HLA DQ2+ Volunteers With Celiac Disease Following a Long-Term, Strict Gluten-Free Diet

2011 ◽  
Vol 140 (5) ◽  
pp. S-437-S-438 ◽  
Author(s):  
Gregor J. Brown ◽  
James Daveson ◽  
Joanne K. Marjason ◽  
Rose A. Ffrench ◽  
Danielle Smith ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Phase I ◽  
Phase I Study ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Hla Dq2

S2041 Improved Performance of Celiac Disease-Related Serology Tests in Predicting the Degree of Patients' Compliance With Long-Term Gluten-Free Diet. New Cut-Offs are Necessary

2010 ◽  
Vol 138 (5) ◽  
pp. S-307
Author(s):  
Fabio D. Nachman ◽  
Emilia Sugai ◽  
Horacio Vázquez ◽  
Andrea F. Gonzalez ◽  
Paola J. Andrenacci ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Improved Performance

Persistent Duodenal Intraepithelial Lymphocytosis Despite a Long-Term Strict Gluten-Free Diet in Celiac Disease

2012 ◽  
Vol 107 (10) ◽  
pp. 1563-1569 ◽  
Author(s):  
Ilus Tuire ◽  
Lähdeaho Marja-Leena ◽  
Salmi Teea ◽  
Haimila Katri ◽  
Partanen Jukka ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Intraepithelial Lymphocytosis

Urinary nitric oxide metabolites in children with celiac disease after long-term consumption of oats-containing gluten-free diet

2014 ◽  
Vol 49 (11) ◽  
pp. 1311-1317 ◽  
Author(s):  
Dimitrios Tapsas ◽  
Karin Fälth-Magnusson ◽  
Lotta Högberg ◽  
Tony Forslund ◽  
Tommy Sundqvist ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Nitric Oxide Metabolites

scholarly journals Cortical involvement in celiac disease before and after long-term gluten-free diet: A Transcranial Magnetic Stimulation study

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177560 ◽  
Author(s):  
Manuela Pennisi ◽  
Giuseppe Lanza ◽  
Mariagiovanna Cantone ◽  
Riccardo Ricceri ◽  
Raffaele Ferri ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Before And After ◽  
Cortical Involvement

M2033 Role of Antibodies in the Long Term Follow Up of Patients with Celiac Disease to Predict the Adherence to Gluten-Free Diet

2009 ◽  
Vol 136 (5) ◽  
pp. A-471
Author(s):  
Adriana Mohaidle ◽  
José M. Mella ◽  
Lisandro Pereyra ◽  
Pablo Luna ◽  
Carolina Fischer ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Long Term Follow Up

Improving gluten free diet adherence by youth with celiac disease

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Dory Sample ◽  
Justine Turner
Keyword(s):  
Celiac Disease ◽  
Personal Autonomy ◽  
Peer Acceptance ◽  
Autoimmune Disorder ◽  
Gluten Free Diet ◽  
Self Management ◽  
Gluten Free ◽  
Diet Adherence ◽  
Management Approaches

Abstract Introduction Celiac disease (CD) is a gluten-triggered autoimmune disorder of the small intestine, which can occur in genetically susceptible individuals at any age. A strict life-long gluten free diet (GFD) is the only medically approved treatment, and non-adherence is associated with significant morbidity. However, gluten use is widespread, complicating efforts to follow the diet. Youth with CD are especially challenged with dietary adherence, as they strive for peer acceptance and personal autonomy in the context of managing a chronic disease. Methods A scoping review was conducted to identify mechanisms to assist youth with remaining gluten free. Results There is a paucity of literature regarding best approaches to improve diet adherence by youth, however, lessons can also be learned by borrowing ideas from self-management approaches of other chronic diseases. Several mechanisms for improving GFD adherence among youth are identified, including regular engagement of the youth with CD and their family with an experienced multidisciplinary team, electronic tool utilization and awareness of accurate resources for self-guided education and resources. Conclusions Improvement in GFD adherence by youth is achievable and may influence long-term health outcomes.

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