scholarly journals A case of undifferentiated carcinoma with lymphoid stroma of the sublingual gland associated with Epstein-Barr virus.

2001 ◽  
Vol 47 (10) ◽  
pp. 611-614 ◽  
Author(s):  
Yuko NISHIYAMA ◽  
Naohisa OKU ◽  
Tomohiro YOSHIKAWA ◽  
Masataka FUKUDA ◽  
Masahiro UMEDA ◽  
...  
1990 ◽  
Vol 99 (3) ◽  
pp. 236-238 ◽  
Author(s):  
Karen R. Cleary ◽  
John G. Batsakis

Undifferentiated carcinoma with lymphoid stroma or lymphoepithelial carcinoma of the major salivary glands is a demographically and histopathologically unique malignancy. Although whites may have the disease, it is preponderantly a carcinoma of North American Eskimos and native Greenlanders. The carcinoma shares many features with undifferentiated nasopharyngeal carcinomas, from which it must be distinguished: histologic appearance, putative relationship with Epstein-Barr virus, predilection for mongoloid races, and response to therapy. In some cases, the carcinoma appears to have evolved from a lymphoepithelial lesion.


1993 ◽  
Vol 107 (12) ◽  
pp. 1177-1179 ◽  
Author(s):  
Ahmet Dündar ◽  
Sefa Dereköy ◽  
Turgut Önder ◽  
Davut Aktas ◽  
Adnan Özünlü

A rare undifferentiated carcinoma with lymphoid stroma (UCLS) of the parotid gland is described in a white Turkish patient. The raised serum IgG to Epstein-Barr virus capsid antigen suggests a causal relationship between Epstein-Barr virus and this type of salivary gland carcinoma. Some clinical features are briefly reviewed.


1994 ◽  
Vol 47 (6) ◽  
pp. 538-540 ◽  
Author(s):  
K Horiuchi ◽  
K Mishima ◽  
M Ohsawa ◽  
K Aozasa

2020 ◽  
Vol 96 (1) ◽  
pp. 93-94
Author(s):  
Akie Sakakura ◽  
Hiroyuki Ariga ◽  
Yuri Kumakura ◽  
Junya Kashimura

1979 ◽  
Vol 16 (2) ◽  
pp. 180-190 ◽  
Author(s):  
A. Pospischil ◽  
T. Haenichen ◽  
H. Schaeffler

In five cases of endemic ethmoidal carcinoma in cattle from the Dominican Republic three tumor types could be classified: undifferentiated carcinoma (3), adenocarcinoma (1), and squamous cell carcinoma (1). Electron microscopy showed that the tumor cells in undifferentiated carcinomas closely resembled the cells of the normal olfactory mucosa. This was especially true for the dark cells of Bowman's gland. Ultrastructurally, the lymphoid cells of the undifferentiated bovine carcinoma resembled the lymphoid cells of human nasopharyngeal carcinoma being closely associated with Epstein-Barr Virus. This and epidemiological observations suggested a viral cause of endemic ethmoidal carcinoma.


2019 ◽  
Vol 7 (9) ◽  
pp. 305 ◽  
Author(s):  
Yanagi ◽  
Nishikawa ◽  
Shimokuri ◽  
Shuto ◽  
Takagi ◽  
...  

: Epstein–Barr virus (EBV) is a ubiquitous human herpes virus, but related with several types of malignancies. Among EBV-related malignancies, EBV-associated gastric carcinoma (EBVaGC) has the largest patient’s number. We screened for EBV infection in 1067 GC lesions of 1132 patients who underwent surgical resection from 2007 to 2017 in Japan and examined clinicopathological features of EBVaGC. EBV infection was detected by in situ hybridization with EBV-encoded small RNA 1(EBER-1 ISH). EBV was infected in 80 GC lesions (7.1%). Mean age was significantly lower in patients with EBVaGC than with EBV-negative GC. EBVaGC was more frequent in men than in women. EBVaGC was found twice as frequent in the upper or middle stomach as in the lower stomach. Early EBVaGC was more frequent, and submucosally invaded cases were dominant. The presence of lymphatic vessel invasion was less in EBVaGC, but frequency of lymph node metastasis was similar. Carcinoma with lymphoid stroma (CLS) was found in 3.8% (43/1132) of all lesions with 60.5% of EBV positivity. The synchronous or metachronous multiple GC was frequent in EBVaGC. We clarified clinicopathologic characteristics of EBVaGC over the past decade in Japan. EBV infection should be examined in gastric cancer cases showing these characteristics.


Sign in / Sign up

Export Citation Format

Share Document