scholarly journals Dermoscopic patterns in active and regressive lichen planus and lichen planus variants: a morphological study

2015 ◽  
pp. 45-53
Author(s):  
Sule Güngör ◽  
Ilteriş O. Topal ◽  
Emek K. Göncü
Keyword(s):  
Lichen Planus ◽  
Skin Disorder ◽  
Morphological Study ◽  
Disease Duration ◽  
Histopathological Examination ◽  
Before And After ◽  
Inflammatory Skin Disorder ◽  
Inflammatory Skin ◽  
Lesion Localization

Background: Lichen planus (LP) is an acute or chronic inflammatory skin disorder characterized by discrete, violaceous, polygonal papules. Objective: In this study, we aimed to categorize the dermoscopic images of LP and LP variants before and after treatment. Methods: We analyzed and categorized the dermoscopic images of 255 LP lesions from 60 patients who had been clinically diagnosed with LP or LP variants and confirmed by histopathological examination. We reanalyzed and categorized the dermoscopic images of 50 lesions from fifteen patients after treatment. Results: We observed different Wickham striae (WS), pigment, and vascular patterns according to the LP variant, lesion localization and disease duration. Reticular, circular, linear, globular, radial streaming, perpendicular, and veil-like (structureless) WS patterns were detected on dermoscopic examination. Peripheral/diffuse dot globules, peripheral/diffuse peppering, perifollicular/annular, linear, reticular, circular, cobblestone, and homogeneous cloud-like pigment patterns were especially prevalent in LP pigmentosus and regressive LP lesions. As for vascular patterns, there were red dots/globules, radial linear, and peripheral homogeneous patterns described upon dermoscopic evaluation. Conclusion: Dermoscopic evaluation can be useful both in the diagnosis and follow up of LP.

scholarly journals Computed Tomography and Bronchoscopy in Endobronchial Tuberculosis

2003 ◽  
Vol 10 (8) ◽  
pp. 445-448 ◽  
Author(s):  
Halil Yanardag ◽  
Cüneyt Tetikkurt ◽  
Seza Tetikkurt ◽  
Sabriye Demirci ◽  
Tuncer Karayel
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Therapeutic Response ◽  
Histopathological Examination ◽  
Computed Tomographic ◽  
Before And After ◽  
Endobronchial Tuberculosis ◽  
Age Range

BACKGROUND: The therapeutic response to endobronchial tuberculosis is usually evaluated by bronchoscopy. Currently, there are no published studies investigating the use of computed tomography for the evaluation of therapeutic response in endobronchial tuberculosis.OBJECTIVE: A retrospective study was performed to evaluate the bronchoscopic and computed tomographic features of endobronchial tuberculosis before and after treatment. The aim of this study was to investigate the usefulness of computed tomography for the assessment of treatment.METHODS: The clinical, pathological and bronchoscopic features of endobronchial tuberculosis were evaluated in 55 patients. The age range of the patients was 21 to 52 years. Computed tomography and bronchoscopy were performed before and after treatment.RESULTS: Diagnosis of tuberculosis was confirmed by culture and histopathological examination. Bronchoscopic examination revealed 89 endobronchial lesions of various types in 55 patients. The exudative type was the most common. Follow-up bronchoscopy revealed that exudative-, ulcerative- and granular-type lesions healed completely. Computed tomography performed after treatment correlated well with the follow-up bronchoscopic findings.CONCLUSION: The results suggest that follow-up computed tomography is useful for the evaluation of therapeutic response and complications associated with endobronchial tuberculosis, and may replace bronchoscopy.

scholarly journals Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Astrid-Helene Ravn Jørgensen ◽  
Yiqiu Yao ◽  
Simon Francis Thomsen
Keyword(s):  
Antibiotic Therapy ◽  
Skin Disorder ◽  
Hidradenitis Suppurativa ◽  
Therapeutic Response ◽  
The Body ◽  
Systemic Antibiotic ◽  
Systemic Antibiotic Therapy ◽  
Inflammatory Skin Disorder ◽  
Inflammatory Skin

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).

Plantar Psoriasis Associated with Olmesartan

2019 ◽  
Vol 14 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Ons Charfi ◽  
Talel Badri ◽  
Ghozlane Lakhoua ◽  
Sarrah Kastalli ◽  
Sihem El Aidli ◽  
...  
Keyword(s):  
Skin Disorder ◽  
Beta Blockers ◽  
Exceptional Case ◽  
Gold Salts ◽  
Inflammatory Skin Disorder ◽  
Inflammatory Skin

Background: Psoriasis is a chronic inflammatory skin disorder that may be initiated or exacerbated by some drug intakes. Some of the most common medications known to trigger or worsen existing psoriasis include lithium, gold salts, beta blockers and antimalarials. Conclusion: We report an exceptional case of plantar psoriasis in a woman who was treated by olmesartan for 3 years.

New aspect of allergic contact dermatitis, an inflammatory skin disorder mediated by mast cells: Can IL-38 help?

2020 ◽  
Vol 139 ◽  
pp. 109687 ◽  
Author(s):  
Dorita Lauritano ◽  
Gianpaolo Ronconi ◽  
Alessandro Caraffa ◽  
Carla Enrica Gallenga ◽  
Spyros K. Kritas ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Mast Cells ◽  
Allergic Contact Dermatitis ◽  
Skin Disorder ◽  
Inflammatory Skin Disorder ◽  
Inflammatory Skin ◽  
Allergic Contact

scholarly journals Granuloma faciale – A case report

2020 ◽  
Vol 0 ◽  
pp. 1-3
Author(s):  
Sumi Thomas
Keyword(s):  
Case Report ◽  
Skin Disorder ◽  
Middle Aged ◽  
Granuloma Faciale ◽  
Inflammatory Skin Disorder ◽  
Inflammatory Skin ◽  
Middle Aged Adults

Granuloma faciale is a rare localized idiopathic inflammatory skin disorder that manifests as reddish-brown or violaceous papules, plaques, or nodules. It usually occurs in middle-aged adults and is rare in children. We are reporting a case of granuloma faciale in a 31-year-old male.

scholarly journals In vivo comparison of braided (Accero) and laser-cut intracranial stents (Acclino, Credo): evaluation of vessel responses at subacute and mid-term follow-up in a rabbit model

2020 ◽  
Vol 31 (12) ◽  
Author(s):  
Mühl-Benninghaus Ruben ◽  
Tomori Toshiki ◽  
Krajewski Stefanie ◽  
Dietrich Philipp ◽  
Simgen Andreas ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Rabbit Model ◽  
Vessel Diameter ◽  
Progressive Increase ◽  
In Vivo Model ◽  
Antiplatelet Medication ◽  
Significant Difference ◽  
Before And After

AbstractThis study aimed to investigate in vivo two stent technologies, with particular emphasis on thrombogenicity and inflammatory vessel remodeling processes. The micro-stents tested in this study were developed for intracranial aneurysm treatment. In our study twelve, New Zealand white rabbits were divided into two groups: 18 laser-cut stents (LCS) and 18 braided stents (BS) were impanated without admiration of antiplatelet medication. Three stents were implanted into each animal in the common carotid artery, subclavian artery, and abdominal aorta. Digital subtraction angiography was performed before and after stent implantation and at follow-up for the visualization of occurring In-stent thromboembolism or stenosis. The Stents were explanted for histopathological examination at two different timepoints, after 3 and 28 days. Angiographically neither in-stent thrombosis nor stenosis for both groups was seen. There was a progressive increase in the vessel diameter, which was more pronounced for BS than for LCS. We detected a higher number of thrombi adherent to the foreign material on day 3 for BS. On day 3, the neointima was absent, whereas the complete formation observed was on day 28. There was no significant difference between both groups regarding the thickness of the neointima. The in vivo model of our study enabled the evaluation of blood and vessel reactions for two different stent technologies. Differences in vessel dimension and tissue around the stents were observed on day 28. Histological analysis on day 3 enabled the assessment of thrombotic reactions, representing an important complementary result in long-term studies.

Sign in / Sign up

Export Citation Format

Share Document