scholarly journals Protective Benefit of Seprafilm® in Reducing Adhesive Small Bowel Obstruction Following Colorectal Cancer Surgery

2017 ◽  
Vol 50 (5) ◽  
pp. 339-349
Author(s):  
Aya Matsui ◽  
Hayato Hosoi ◽  
Junkichi Koinuma ◽  
Kazuaki Hazama ◽  
Kazuhiro Iwai ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Hideo Yasunaga ◽  
Hiroaki Miyata ◽  
Hiromasa Horiguchi ◽  
Kazuaki Kuwabara ◽  
Hideki Hashimoto ◽  
...  

Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propensity-score-matched patients with early postoperative ASBO following colorectal cancer surgery, who received long-tube decompression (LTD) with or without Dai-kenchu-to administration. The success rates of LTD were not significantly different between Dai-kenchu-to users and nonusers (84.7% versus 78.5%;P=.224), while Dai-kenchu-to users showed a shorter duration of LTD (8 versus 10 days;P=.012), shorter duration between long-tube insertion and discharge (23 versus 25 days;P=.018), and lower hospital charges ($23,086 versus$26,950;P=.018) compared with Dai-kenchu-to nonusers. In conclusion, the present study suggests that Dai-kenchu-to is effective for reducing the duration of LTD and saving costs.


1995 ◽  
Vol 48 (2) ◽  
pp. 137-143 ◽  
Author(s):  
H. Katoh ◽  
H. Sugiyama ◽  
H. Nakamura ◽  
Y. Torigoshi ◽  
K. Tsujita ◽  
...  

2019 ◽  
Vol 229 (4) ◽  
pp. S87
Author(s):  
Jose A. Aldana ◽  
Javier E. Rincon ◽  
Ricardo A. Fonseca ◽  
Rohit K. Rasane ◽  
Christina X. Zhang ◽  
...  

2021 ◽  
pp. 145749692098276
Author(s):  
M. Podda ◽  
M. Khan ◽  
S. Di Saverio

Background and Aims: Approximately 75% of patients admitted with small bowel obstruction have intra-abdominal adhesions as their cause (adhesive small bowel obstruction). Up to 70% of adhesive small bowel obstruction cases, in the absence of strangulation and bowel ischemia, can be successfully treated with conservative management. However, emerging evidence shows that surgery performed early during the first episode of adhesive small bowel obstruction is highly effective. The objective of this narrative review is to summarize the current evidence on adhesive small bowel obstruction management strategies. Materials and Methods: A review of the literature published over the last 20 years was performed to assess Who, hoW, Why, When, What, and Where diagnose and operate on patients with adhesive small bowel obstruction. Results: Adequate patient selection through physical examination and computed tomography is the key factor of the entire management strategy, as failure to detect patients with strangulated adhesive small bowel obstruction and bowel ischemia is associated with significant morbidity and mortality. The indication for surgical exploration is usually defined as a failure to pass contrast into the ascending colon within 8–24 h. However, operative management with early adhesiolysis, defined as operative intervention on either the calendar day of admission or the calendar day after admission, has recently shown to be associated with an overall long-term survival benefit compared to conservative management. Regarding the surgical technique, laparoscopy should be used only in selected patients with an anticipated single obstructing band, and there should be a low threshold for conversion to an open procedure in cases of high risk of bowel injuries. Conclusion: Although most adhesive small bowel obstruction patients without suspicion of bowel strangulation or gangrene are currently managed nonoperatively, the long-term outcomes following this approach need to be analyzed in a more exhaustive way, as surgery performed early during the first episode of adhesive small bowel obstruction has shown to be highly effective, with a lower rate of recurrence.


2018 ◽  
Vol 226 (6) ◽  
pp. 968-976.e1 ◽  
Author(s):  
Alexander S. Chiu ◽  
Raymond A. Jean ◽  
Kimberly A. Davis ◽  
Kevin Y. Pei

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