Exploring the Histogenesis of Ovarian Mucinous and Transitional Cell (Brenner) Neoplasms and Their Relationship With Walthard Cell Nests: A Study of 120 Tumors

2008 ◽  
Vol 132 (11) ◽  
pp. 1753-1760 ◽  
Author(s):  
Jeffrey D. Seidman ◽  
Fatemeh Khedmati

Abstract Context.—The origin of and relationship between ovarian mucinous and transitional cell (Brenner) neoplasms are enigmatic. The reported association ranges from 1% to 16%, and whether there is an association with Walthard cell nests is unknown. Objective.—To clarify the histologic relationship between mucinous and Brenner tumors. Design.—A total of 40 mucinous cystadenomas, 67 Brenner tumors, and 13 combined tumors were studied. Peritoneal surfaces were examined for Walthard nests in 83 patients compared with 272 controls. Results.—A total of 25% of tumors with a mucinous component contained a Brenner component, and 16% of tumors with a Brenner component contained a mucinous component. Most calcifications were spiculated (nonpsammomatous). In 6 combined tumors, the relative volume of the 2 components was less than 1:3000 (transitional-mucinous). Walthard nests were found in 50% of patients with Brenner tumors and 59% of patients with mucinous tumors. This was significantly higher than the 28% found in controls (P = .002 and P < .001, respectively). The number of fallopian tube blocks examined was correlated with the likelihood of finding Walthard nests, and accordingly, sampling accounted for 39% of the increase with Brenner tumors but strengthened the association with mucinous tumors. Conclusions.—The strong association of mucinous and transitional cell components, similar type of calcification, complementary size distributions, and frequent identification of a transitional component in the face of an exceedingly small estimated proportion of that component suggest that this association has been underestimated. The association of Brenner tumors with Walthard nests, although significant, appears weak and not strongly supportive of a histogenetic relationship. The stronger association of Walthard nests with mucinous tumors remains unexplained.

Author(s):  
Natasha Mittal ◽  
Bhaskar Das ◽  
Seema Manuja ◽  
Renu Gupta

Brenner tumors are rare ovarian tumors, which are a subgroup of transitional cell tumors of ovary. Most of these tumors are benign presenting as incidental unilateral masses in postmenopausal age group. Only 5-7% cases are bilateral. These tumors are mostly small, solid and asymptomatic, seen commonly in association with mucinous cystadenomas of ovary. In such cases they may attain a massive size. Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological examination. Surgical removal is usually curative for benign tumors. We present a rare case of bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma in which bilateral Brenner tumor was a rare incidental finding on pathological examinatio


Oryx ◽  
2019 ◽  
Vol 53 (3) ◽  
pp. 439-449 ◽  
Author(s):  
Roderick J. Fensham ◽  
Jason Halford ◽  
Chris Hansen ◽  
Boris Laffineur ◽  
Billie Williams

AbstractPlant biodiversity is threatened by habitat loss, fragmentation and invasion by exotic species, but the effects of these disturbances on individual plant species are rarely quantified. Since the 1950s, brigalow Acacia harpophylla forests in Australia have been extensively cleared and converted to pastures dominated by exotic grasses. Here we assess the habitat requirements, population numbers and threats for four poorly known bush tomato species, Solanum adenophorum, Solanum dissectum, Solanum elachophyllum and Solanum johnsonianum. Herbarium records and surveys demonstrated a strong association of all four species with brigalow habitat, although S. elachophyllum also occurred in other habitat. We derived historical and current population estimates from plant densities at current sites and the area of mapped brigalow habitat. Density estimates are imprecise because the survey data vary greatly, but the assessment indicates the populations of all four species have declined > 93%. Solanum dissectum and S. johnsonianum did not persist in cleared brigalow habitat, whereas S. adenophorum and S. elachophyllum had some capacity to persist in clearings. None of the species occur where the exotic grass cover is > 40%. Between 27% and 57% of the records of the four species are in brigalow remnants with a high edge-to-area ratio or open canopy (< 50% cover), making them highly vulnerable to invasive grasses. We recommend the categorization of S. dissectum and S. johnsonianum as Critically Endangered, S. adenophorum as Vulnerable and S. elachophyllum as Near Threatened.


2001 ◽  
Vol 438 (2) ◽  
pp. 181-191 ◽  
Author(s):  
Ina Riedel ◽  
Bernard Czernobilsky ◽  
Beatriz Lifschitz-Mercer ◽  
Lawrence M. Roth ◽  
Xue-Ru Wu ◽  
...  

2019 ◽  
Vol 10 (3) ◽  
Author(s):  
Mariana Gonçalves De Oliveira ◽  
Raquel Silva Teixeira ◽  
Vandilene Nogueira Menezes Costa ◽  
Paulo Henrique Lima De Alencar ◽  
Elessandra Oliveira Rodrigues ◽  
...  

Objetivo: descrever sentimentos de mulheres com depressão pós-parto frente ao aleitamento materno. Metodologia: estudo qualitativo, descritivo e exploratório, com 20 mulheres com depressão pós-parto, entre abril e maio de 2017 em Fortaleza- CE. Para coletar dados realizou-se entrevista, roteiro sociodemográfico e obstétrico e relatos gravados e analisados por método de Bardin. Resultados: as dificuldades da depressão pós-parto no aleitamento são: falta de condições psicológicas, desencantamento e sentimentos como estresse, medo e tristeza. Conclusão: Constatou-se que mulheres com depressão pósparto sofreram impacto negativo durante o aleitamento, é essencial a atenção a sentimentos depressivos entre puérperas, devido forte relação ao desmame precoce.Descritores: Aleitamento Materno; Depressão Pós-Parto; Obstetrícia, Saúde da Mulher.FEELINGS OF WOMEN WITH POSTPARTUM DEPRESSION IN FRONT OF MATERNAL BREASTFEEDINGObjective: To describe the feelings of women with postpartum depression in the face of breastfeeding. Methodology: This is a qualitative, descriptive and exploratory study, carried out in Fortaleza-CE, with 20 women who have or had postpartum depression. Results: The difficulties of postpartum depression in breastfeeding according to the interviewees were: lack of psychological conditions, difficulty in contact with the child, disenchantment, and feelings such as stress, fear, sadness, involved in the moment of breastfeeding. Conclusion: The present study found that women with postpartum depression had a negative impact during breastfeeding. More attention is needed to the mental health of the women, considering the depressive symptoms present in puerperas and the strong association with the shorter breastfeeding time.Descriptors: Breastfeeding; Postpartum Depression; Obstetrics; Women’s Health.SENTIMIENTOS DE MUJERES CON DEPRESIÓN POST-PARTO FRENTE AL ALCANCE MATERNOObjetivo: describir los sentimientos de mujeres con depresión posparto frente a la lactancia materna. Metodología: Se trata de un estudio cualitativo, descriptivo y exploratorio, realizado en Fortaleza-CE, con 20 mujeres que tienen o tuvieron depresión posparto. Resultados: Las dificultades de la depresión posparto en la lactancia materna según las entrevistadas fueron: falta de condiciones psicológicas, dificultad en el contacto con el niño, desencanto, y sentimientos como estrés, miedo, tristeza, involucrados en el momento de la lactancia. Conclusión: El presente estudio constató que las mujeres con depresión posparto sufrieron un impacto negativo durante la lactancia. Se hace necesaria una mayor atención a la salud mental de las mujeres, considerando los síntomas depresivos presentes en puérperas y la fuerte asociación con el menor tiempo de lactancia materna.Descriptores: Lactancia Materna; Depresión Post-Parto; Obstetricia; Salud de la Mujer.


Morphologia ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 35-41
Author(s):  
O. I. Makarchuk ◽  
Yu. V. Silkina ◽  
I. V. Tverdokhlib

Background. Improvement of the technical aspects of surgery in aesthetic surgery led to an increase in the number of transactions and significant increase contingent of women who are turning to specialized clinics. But it also significantly increased the proportion of patients with a variety of concomitant diseases requiring new approaches to operational technologies and special attention in the postoperative period. In this group of patients is high risk of intraoperative and postoperative complications significantly limits the range of indications. So to prevent these complications is an important question when planning operations in aesthetic surgery of the face. Objective. Determine structural and functional changes of temporal area skin in women of different age groups with an additional internal pathology. Methods. Intraoperative biopsy material of skin of 104 women at the age from 19 to 73 years, that was taken during standard surgery instrumentations for different defects of face skin correction, was investigated. Results and conclusion. It was determined, that involutive dynamic of microvessel condition in papillary layer of derma coincides with grade reduction of relative volume of microvessels bed. Microcirculation age changes include structural disorders of intrapapillary capillary loops, disorganization of arterioles in papillary and reticular layers of derma, disorders of venules because of the changes in microenvironmental fibrillar network. It is typical at the patients with nicotinic dependence, ischemic heart disease, hypertonic disease, a diabetes, and also adiposity of a different degree essential infringement of microvessels bed structure criteria of skin condition that gives the basis for allocation of the given contingent of patients as group of high intraoperative and postoperative risk at carrying out of frontlift.


Author(s):  
Himchan Jeong ◽  
Guojun Gan ◽  
Emiliano A. Valdez

For automobile insurance, it has long been implied that when a policyholder made at least one claim in the prior year, the subsequent premium is likely to increase. When this happens, the policyholder may seek to switch to another insurance company to possibly avoid paying for a higher premium. In such situations, insurers may be faced with the challenges of policyholder retention by keeping premiums low in the face of competition. In this paper, we seek to find empirical evidence of possible association between policyholder switching after a claim and the associated change in premium. In accomplishing this goal, we employ the method of association rule learning, a data mining technique that has its origins in marketing for analyzing and understanding consumer purchase behavior. We apply this unique technique in two stages. In the first stage, we identify policyholder and vehicle characteristics that affect the size of the claim and resulting change in premium regardless of policy switch. In the second stage, together with policyholder and vehicle characteristics, we identify the association among the size of the claim, the level of premium increase and policy switch. This empirical process is often challenging to insurers because they are unable to observe the new premium for those policyholders who switched. However, we used a 9-year claims data for the entire Singapore automobile insurance market that allowed us to track information before and after the switch. Our results provide evidence of a strong association among the size of the claim, the level of premium increase and policy switch. We attribute this to the possible inefficiency of the insurance market because of the lack of sharing and exchange of claims history among the companies.


2017 ◽  
Vol 56 (10) ◽  
pp. 758-766 ◽  
Author(s):  
Nicole Pfarr ◽  
Silvia Darb-Esfahani ◽  
Jonas Leichsenring ◽  
Eliane Taube ◽  
Melanie Boxberg ◽  
...  

2014 ◽  
Vol 42 (8) ◽  
pp. 660-663 ◽  
Author(s):  
Rohit Inder Singh ◽  
Lauren Rosen ◽  
Vijaya B. Reddy ◽  
Pincas Bitterman ◽  
Matthew H. Stemm ◽  
...  

2010 ◽  
Vol 22 (3) ◽  
pp. 457-473 ◽  
Author(s):  
Jennifer A. Mangels ◽  
Alberto Manzi ◽  
Christopher Summerfield

In social interactions, it is often necessary to rapidly encode the association between visually presented faces and auditorily presented names. The present study used event-related potentials to examine the neural correlates of associative encoding for multimodal face–name pairs. We assessed study-phase processes leading to high-confidence recognition of correct pairs (and consistent rejection of recombined foils) as compared to lower-confidence recognition of correct pairs (with inconsistent rejection of recombined foils) and recognition failures (misses). Both high- and low-confidence retrieval of face–name pairs were associated with study-phase activity suggestive of item-specific processing of the face (posterior inferior temporal negativity) and name (fronto-central negativity). However, only those pairs later retrieved with high confidence recruited a sustained centro-parietal positivity that an ancillary localizer task suggested may index an association-unique process. Additionally, we examined how these processes were influenced by massed repetition, a mnemonic strategy commonly employed in everyday situations to improve face–name memory. Differences in subsequent memory effects across repetitions suggested that associative encoding was strongest at the initial presentation, and thus, that the initial presentation has the greatest impact on memory formation. Yet, exploratory analyses suggested that the third presentation may have benefited later memory by providing an opportunity for extended processing of the name. Thus, although encoding of the initial presentation was critical for establishing a strong association, the extent to which processing was sustained across subsequent immediate (massed) presentations may provide additional encoding support that serves to differentiate face–name pairs from similar (recombined) pairs by providing additional encoding opportunities for the less dominant stimulus dimension (i.e., name).


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