Plasmablastic Lymphoma of the Lung

2001 ◽  
Vol 125 (2) ◽  
pp. 282-285 ◽  
Author(s):  
Yuan Lin ◽  
Gilberto D. Rodrigues ◽  
John F. Turner ◽  
Mohammad A. Vasef
Keyword(s):  
Hodgkin Lymphoma ◽  
Acquired Immunodeficiency Syndrome ◽  
Lung Tumor ◽  
B Cell Lymphoma ◽  
Plasmablastic Lymphoma ◽  
Non Hodgkin Lymphoma ◽  
First Case ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Distinct Subtype

Abstract Non-Hodgkin lymphomas associated with acquired immunodeficiency syndrome are heterogeneous. Recently, a novel subtype of non-Hodgkin lymphoma occurring mostly in patients with acquired immunodeficiency syndrome has been described and designated as plasmablastic lymphoma. The histomorphologic and immunophenotypic findings of this distinct subtype of non-Hodgkin lymphoma have been characterized previously. Most patients present with oral cavity involvement. We report a case of plasmablastic lymphoma presenting as a lung tumor. To our knowledge, this is the first case report of this unusual subtype of diffuse large B-cell lymphoma in this location.

A CASE OF ACQUIRED IMMUNODEFICIENCY SYNDROME ASSOCIATED WITH FULMINANT HEPATITIS AND NON HODGKIN LYMPHOMA

1994 ◽  
Vol 44 (4) ◽  
pp. 421-427
Author(s):  
SHUICHI SAITOH ◽  
FUJIO MAKITA ◽  
TORU OJIMA ◽  
NORIFUMI TSUKAMOTO ◽  
SHOJI YAMADA ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Acquired Immunodeficiency Syndrome ◽  
Fulminant Hepatitis ◽  
Non Hodgkin Lymphoma ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

scholarly journals Non-Hodgkin lymphoma in people living with human immunodeficiency syndrome

2020 ◽  
Vol 73 (1-2) ◽  
pp. 37-42
Author(s):  
Vanja Andric ◽  
Vesna Turkulov ◽  
Ivana Urosevic ◽  
Nebojsa Salaj ◽  
Nikola Boskovic ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Mortality Rate ◽  
Cell Count ◽  
Hodgkin Lymphoma ◽  
Acquired Immunodeficiency Syndrome ◽  
Non Hodgkin Lymphoma ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Introduction. Even in the era of combined antiretroviral therapy, the mortality rate in patients with human immunodeficiency virus infection remains high, especially with a contributing diagnosis of a malignant disease, such as non-Hodgkin lymphoma. Given the previous, the goal of this research was to establish the incidence of non-Hodgkin lymphoma in human immunodeficiency virus positive patients, as well as to determine their clinical characteristics and mortality in regard to patients with human immunodeficiency virus only. Material and Methods. The retrospective study included 396 human immunodeficiency virus-positive patients. Medical records were reviewed to analyze the average age, duration of infection, average duration of therapy, nCD4+ T-cell count, human immunodeficiency virus viral load, as well as the number and types of malignant diseases. Results. The average age of the patients was 44.2 years; the average nCD4+ T-cell count was 296.94 cells/?L, while the mortality rate was 14.65%. The leading causes of death were non-Hodgkin lymphoma and acquired immunodeficiency syndrome. The most frequently diagnosed malignancy was non-Hodgkin lymphoma, where the average count of nCD4+ T-cells was 162.29 cells/?L. Patients with human immunodeficiency virus and non-Hodgkin lymphoma had significantly lower nCD4+ T-cell count, in regard to patients with human immunodeficiency virus only, and the mortality rate in this group of patients was 85%. Conclusion. The incidence of non-Hodgkin lymphoma in human immunodeficiency virus-positive patients represents a growing threat, given the exceptionally high mortality. The nCD4+ T-cell count may indicate acquired immunodeficiency syndrome and late diagnosis of human immunodeficiency virus together are predictors for non-Hodgkin lymphoma and its poor outcome. It points to the importance of increasing the scope of human immunodeficiency virus testing, as well as finding a better treatment approach.

scholarly journals Circulating cytokine levels, Epstein-Barr viremia, and risk of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma

2011 ◽  
Vol 86 (10) ◽  
pp. 875-878 ◽  
Author(s):  
Charles S. Rabkin ◽  
Eric A. Engels ◽  
Ola Landgren ◽  
Rob Schuurman ◽  
M. Constanza Camargo ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Acquired Immunodeficiency Syndrome ◽  
Non Hodgkin Lymphoma ◽  
Cytokine Levels ◽  
Acquired Immunodeficiency ◽  
Epstein Barr ◽  
Immunodeficiency Syndrome

scholarly journals Non-Hodgkin’s Plasmablastic Lymphoma as Initial Presentation of Human Immunodeficiency Virus

2021 ◽  
Vol 9 ◽  
pp. 232470962110146
Author(s):  
Roopam Jariwal ◽  
Nadia Raza ◽  
Janpreet Bhandohal ◽  
Everardo Cobos
Keyword(s):  
Human Immunodeficiency Virus ◽  
Acquired Immunodeficiency Syndrome ◽  
Initial Presentation ◽  
Plasmablastic Lymphoma ◽  
Healthy Male ◽  
Immunodeficiency Virus ◽  
Life Threatening ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Head Neck

Plasmablastic lymphoma (PBL) is a subtype of non-Hodgkin’s lymphoma that manifests in patients with the diagnosis of human immunodeficiency virus (HIV), more prominently in the head, neck, and oral mucosal region. The diagnosis of this rare lymphoma serves as a concomitant diagnosis of acquired immunodeficiency syndrome. The case is of a 33-year-old previously healthy male, with an unknown diagnosis of HIV with a painful right mandibular mass. He was subsequently diagnosed with PBL and HIV. This case of PBL illustrates the importance of linking a rare and potentially life-threatening diagnosis as a possible first manifestation of HIV.

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