Evidence-Based Pathology: Systematic Literature Reviews as the Basis for Guidelines and Best Practices

2015 ◽  
Vol 139 (3) ◽  
pp. 394-399 ◽  
Author(s):  
Alberto M. Marchevsky ◽  
Mark R. Wick

Context Evidence-based medicine has been proposed as a new paradigm for the identification and evaluation of medical information. Best available evidence or data are identified and used as the basis for the diagnosis and treatment of individual patients. Evidence-based pathology has adapted basic evidence-based medicine concepts to the specific needs of pathology and laboratory medicine. Objectives To briefly review the history and basic concepts of evidence-based medicine and evidence-based pathology, describe how to perform and interpret systematic reviews, and discuss how to integrate best evidence into guidelines. Data Sources PubMed (National Library of Medicine, Washington, DC) and Web of Science (Thompson Reuters, New York, New York) were used. Conclusions Evidence-based pathology provides methodology to evaluate the quality of information published in pathology journals and apply it to the diagnosis of tissue samples and other tests from individual patients. Information is gathered through the use of systematic reviews, using a method that is less biased and more comprehensive than ad hoc literature searches. Published data are classified into evidence levels to provide readers with a quick impression about the quality and probable clinical validity of available information. Best available evidence is combined with personal experience for the formulation of evidence-based, rather than opinion-based, guidelines that address specific practice needs.

2011 ◽  
pp. 404-413
Author(s):  
Jane Moon

There has been an explosion in the number of different types of portals in the last decade, and at the same time there has been a lot of confusion with them, especially in relation to the enormous number of portals and their differences from Web sites or Web-pages. This coincides with increased use by consumers seeking medical information on the Internet, and with the important role played by medical portals for evidence based medicine. This article explores current portal technology available from an evaluation of market leaders in the industry and identifies important functional components that are necessary in building an intelligent portal to assist users seeking information on the Internet. The emphasis will be on government to consumer portals (G2C) and uses two reputable government portals Betterhealth and Healthinsite as examples to discuss issues involved with those.


2020 ◽  
Vol 7 ◽  
pp. 238212052095969
Author(s):  
Diana Kantarovich ◽  
Hanna B Vollbrecht ◽  
Sebastian A Cruz ◽  
Hector Castillo ◽  
Cody S Lee ◽  
...  

Objective: Wikipedia is commonly used to acquire information about various medical conditions such as chronic pain. Ideally, better online pain management content could reduce the burden of opioid use disorders. Our goal was to improve the quality of the content available on Wikipedia to make it more accurate and applicable to medical students and the general public while training medical students to practice evidence-based medicine and critically assess their sources of information. Methods: An elective class in Neuroscience, Pain, and Opioids composed of 10 medical students met biweekly to discuss landmark and practice-changing research articles in the fields of acute pain, chronic pain, and opioid management. The professor chose Wikipedia articles relevant to this course. Three independent viewers analyzed the quality of citations, anecdotal medical content, and content value for both patients and medical professionals. As part of their coursework, students then edited the Wikipedia articles. Results: Although some of the Wikipedia pain topic content (6.7% ± 2.0) was anecdotal, financially biased, or inconsistent with Western Medical Practice content, overall articles included primarily high-quality citations (85.6% ± 3.1). On a 0-5 Likert scale, students felt content would be moderately helpful for both medical students/professionals (3.4 ± 0.2) and laypersons (3.5 ± 0.2). Editing and adding citations was feasible, but novel material was often reverted. Conclusion: A significant amount of pain medicine content was relevant and amenable to student editing. Therefore, future use of this tactic could provide a unique opportunity to integrate evidence-based medicine into the medical curriculum and have a direct impact on the widely available medical information. Future refinement in the editorial process may also further improve online information.


Neurosurgery ◽  
2020 ◽  
Vol 87 (3) ◽  
pp. 435-441 ◽  
Author(s):  
Victor M Lu ◽  
Christopher S Graffeo ◽  
Avital Perry ◽  
Michael J Link ◽  
Fredric B Meyer ◽  
...  

Abstract Systematic reviews and meta-analyses in the neurosurgical literature have surged in popularity over the last decade. It is our concern that, without a renewed effort to critically interpret and appraise these studies as high or low quality, we run the risk of the quality and value of evidence-based medicine in neurosurgery being misinterpreted. Correspondingly, we have outlined 4 major domains to target in interpreting neurosurgical systematic reviews and meta-analyses based on the lessons learned by a collaboration of clinicians and academics summarized as 4 pearls. The domains of (1) heterogeneity, (2) modeling, (3) certainty, and (4) bias in neurosurgical systematic reviews and meta-analyses were identified as aspects in which the authors’ approaches have changed over time to improve robustness and transparency. Examples of how and why these pearls were adapted were provided in areas of cranial neuralgia, spine, pediatric, and neuro-oncology to demonstrate how neurosurgical readers and writers may improve their interpretation of these domains. The incorporation of these pearls into practice will empower neurosurgical academics to effectively interpret systematic reviews and meta-analyses, enhancing the quality of our evidence-based medicine literature while maintaining a critical focus on the needs of the individual patients in neurosurgery.


2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Sungmi Lian

Complementary and alternative medicine (CAM) is no longer new terminology in the healthcare system but,evidence-based CAMis still an unfamiliar term. Evidence-based medicine, a practice of medicine based on the recommendation derived from a systematic, scientific study of published data, is accepted as the standard in the healthcare.ACP Evidence-Based Guide to Complementary and Alternative Medicineby Bradly Jacobs and Katherine Gundling is reviewed. Up-to-date reference books like theACP Evidence-Based Guide to Complementary and Alternative Medicineis an essential tool for improving quality of care when the providers aim to practice evidence-based medicine.


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