scholarly journals Mucinous Cystadenoma of the Urachus and Review of Current Classification of Urachal Mucinous Cystic Neoplasms

2018 ◽  
Vol 143 (2) ◽  
pp. 258-263
Author(s):  
Diping Wang ◽  
Norbert Sule
Keyword(s):  
Mucinous Cystadenoma ◽  
Malignant Potential ◽  
World Health ◽  
Mucinous Cystadenocarcinoma ◽  
Cystic Tumor ◽  
Mucinous Cystic Tumor ◽  
Cystic Neoplasms ◽  
Mucinous Cystic Neoplasms ◽  
Low Malignant Potential ◽  
Health Organization

Urachal neoplasms are uncommon and represent a minor portion of bladder tumors. According to the recently updated World Health Organization classification (2016), these tumors are classified as adenomas, adenocarcinomas, nonglandular neoplasms, and mixed carcinomas. The mucinous cystic neoplasms represent a small percentage of urachal tumors with morphologic spectrum ranging from benign mucinous cystadenoma to borderline mucinous cystic tumor of low malignant potential and to malignant mucinous cystadenocarcinoma. Benign urachal mucinous cystic adenomas are exceedingly rare, and only a few cases have been reported in the literature to date. The goal of this review is to summarize the clinical features, histopathologic characteristics, treatment, and prognosis of urachal mucinous cystadenoma in light of differentiating them from mucinous cystic tumor of low malignant potential and mucinous cystadenocarcinoma.

scholarly journals Urachal mucinous cystic tumor of low malignant potential in a polymorbid female: a case report and review of the literature

2022 ◽  
Author(s):  
Benjamin Schmeusser ◽  
Joseph Wiedemer ◽  
Dana Obery ◽  
Kaila Buckley ◽  
Michael Yu
Keyword(s):  
Surgical Excision ◽  
Academic Community ◽  
Malignant Potential ◽  
Cystic Tumor ◽  
Surgical Removal ◽  
Mucinous Cystic Tumor ◽  
Urinary Tract Symptoms ◽  
Low Malignant Potential ◽  
Clinical Considerations ◽  
Cure Rates

AbstractNeoplasms of the urachus are exceedingly rare, representing 0.17% of all bladder cancers. The mucinous cystic tumor of low malignant potential (MCTLMP) subtype is particularly rare with just 25 previous cases reported in the literature. Although rare, MCTLMPs are important to identify due to potential devastating complications and good cure rates with surgical removal. We present a 43 year old female with a nuanced constellation of comorbidities and confirmed MCTLMP following a workup for abdominal pain and irritative lower urinary tract symptoms. Notably, this tumor did not change in size over a 3-year course of serial imaging prior to surgical excision. This urachal MCTLMP represents roughly the 26th and one of the smallest of its subtype reported in the literature. This case illustrates the diagnosis and management of this rare urachal MCTLMP. Individual patient medical history, clinical considerations, and neoplasm characteristics are examined. Although rare, the potential for increased malignancy and potential complications necessitates surgical management and further investigation by the academic community.

scholarly journals Urachal Mucinous Cystic Tumor of Low Malignant Potential with Concurrent Sigmoid Colon Adenocarcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Kelly Brennan ◽  
Paul Johnson ◽  
Heather Curtis ◽  
Thomas Arnason
Keyword(s):  
Sigmoid Colon ◽  
Incidental Finding ◽  
Colon Adenocarcinoma ◽  
Malignant Potential ◽  
Cystic Tumor ◽  
Mucinous Cystic Tumor ◽  
Therapeutic Implications ◽  
Diagnostic Pitfall ◽  
Low Malignant Potential ◽  
Peritoneal Spread

Urachal mucinous tumors are rare neoplasms with behaviour that can range from relatively benign to malignancy that can spread distantly or throughout the peritoneum as pseudomyxoma peritonei or peritoneal carcinomatosis. Here we describe a unique case of urachal mucinous cystic tumor of low malignant potential confined to an intact cyst at the dome of the urinary bladder, without rupture or peritoneal spread. The urachal mucinous tumor was an incidental finding on a staging CT scan performed for sigmoid colon adenocarcinoma. We believe that this case illustrates a potential diagnostic pitfall which could have prognostic and therapeutic implications. Due to the intestinal phenotype of these neoplasms, a urachal tumor of low malignant potential could be mistaken for metastatic spread from a colonic adenocarcinoma in the rare situation such as this case, where the two neoplasms occur concurrently.

scholarly journals LARGE PAPILLARY UROTHELIAL NEOPLASM OF LOW MALIGNANT POTENTIAL: A CASE REPORT

2018 ◽  
Vol 14 (3) ◽  
pp. 139-142
Author(s):  
A. A. Tomilov ◽  
I. V. Seregin ◽  
E. I. Veliev ◽  
O. V. Paklina ◽  
G. R. Setdikova
Keyword(s):  
Case Report ◽  
World Health Organization ◽  
International Society ◽  
Clinical Case ◽  
Malignant Potential ◽  
Tumor Classification ◽  
World Health ◽  
Low Malignant Potential ◽  
Health Organization ◽  
Urothelial Neoplasm

Last World Health Organization 2016/ISUP (International Society of Urologic Pathologists) papillary urinary tumor classification include papillary urothelial neoplasm of low malignant potential (PUNLMP).  This type of tumor is characterized by minimal atypia as well as low recurrence and progression rates. The article describes a clinical case of large PUNLMP treatment.

Primary retroperitoneal mucinous cystic tumor of low malignant potential-A case report-

2008 ◽  
Vol 47 (5) ◽  
pp. 372-376
Author(s):  
Noriko ABE ◽  
Syouichiro SANADA ◽  
Tomoko HARADA ◽  
Tatsunari SATAKE ◽  
Nobuo NAKASHIMA ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Potential ◽  
Cystic Tumor ◽  
Mucinous Cystic Tumor ◽  
Low Malignant Potential ◽  
Primary Retroperitoneal

scholarly journals Urothelial Proliferation of Unknown Malignant Potential Involving the Bladder: Histopathologic Features and Risk of Progression in De Novo Cases and Cases With Prior Neoplasia

2019 ◽  
Vol 144 (7) ◽  
pp. 853-862
Author(s):  
Brett M. Lowenthal ◽  
Debashis Sahoo ◽  
Mahul B. Amin ◽  
Donna E. Hansel
Keyword(s):  
Median Time ◽  
De Novo ◽  
Clinical Findings ◽  
Malignant Potential ◽  
World Health ◽  
Time To Progression ◽  
Risk Of Progression ◽  
Health Organization ◽  
Subsequent Risk

Context.— Urothelial proliferation of unknown malignant potential (UPUMP) is a 2016 World Health Organization classifier that encompasses prior categories of flat and papillary urothelial hyperplasia. In addition, UPUMP occurs in settings of both de novo and prior bladder neoplasia. Objective.— To identify UPUMP features associated with subsequent neoplastic development. Design.— Sixty-eight patients were identified from the archives, including 26 patients with de novo and 42 patients with prior bladder neoplasia. Patient slides and clinical course were reviewed. Results.— Patients with de novo UPUMP were detected through clinical findings (26/26; 100%), whereas surveillance cystoscopy primarily detected UPUMP in patients with prior neoplasia (29/42; 69%). Histopathologic criteria evaluated included urothelial hyperplasia, urothelial cytology, vascular ingrowth, denudation, inflammation, edema, and fibrosis. Mean clinical follow-up was 68.9 months in patients with de novo neoplasia and 69.5 months in patients with prior neoplasia. Subsequent neoplasia developed in 4 of 26 (15.4%) of patients with de novo UPUMP and was associated with cystoscopic papillary appearance (P = .02) or microscopic thin papillary ingrowths or papillations (P = .02; median time to progression, 4.1 months). Of 42 patients with prior neoplasia, 17 (40.5%) had subsequent neoplasia, significantly associated with an absence of prominent lamina propria edema (P < .001; median time to progression, 11.0 months). A higher rate of progression to high-grade disease was present in patients with a prior neoplasia versus those with de novo disease (58.9% versus 25%). Conclusions.— Urothelial proliferation of unknown malignant potential shows subsequent risk of neoplastic development of 17% in patients with de novo disease and 40% in patients with prior neoplasia. The greatest risk of progression is associated with early papillary formation.

Giant ovarian cysts: Is a pre- and intraoperative drainage an advisable procedure?

2006 ◽  
Vol 16 (6) ◽  
pp. 2039-2043 ◽  
Author(s):  
J. Einenkel ◽  
H. Alexander ◽  
D. Schotte ◽  
P. Stumpp ◽  
L.-C. Horn
Keyword(s):  
Critical Evaluation ◽  
Mucinous Cystadenoma ◽  
Malignant Potential ◽  
Ovarian Cysts ◽  
The Past ◽  
Considerable Debate ◽  
Low Malignant Potential ◽  
Definitive Surgery

There has been a considerable debate over the merits of a pre- or intraoperative drainage of giant ovarian cysts, which represented a very frequent approach before definitive surgery in the past. Including our presented case of a 57-year-old woman with a 49 kg mucinous cystadenoma, 19 patients with giant ovarian cysts weighing more than 40 kg were reported in the literature since 1970. An incidence of 37% of malignant and low malignant potential tumors was found. Based on a critical evaluation of the medical courses and the discussed miscellaneous advantages and complications, we conclude that a pre- and intraoperative drainage should be avoided.

scholarly journals Oral Lichen Planus as a Preneoplastic Inflammatory Model

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Eleni A. Georgakopoulou ◽  
Marina D. Achtari ◽  
Michael Achtaris ◽  
Periklis G. Foukas ◽  
Athanassios Kotsinas
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Malignant Potential ◽  
World Health ◽  
Unknown Etiology ◽  
The Past ◽  
Long Run ◽  
Potentially Malignant ◽  
Health Organization ◽  
Oral Lichen

Oral lichen planus (OLP) is a chronic oral inflammatory disease of unknown etiology. According to reports, 1-2% of OLP patients develop oral squamous cell carcinoma (OSCC) in the long run. While World Health Organization (WHO) classifies OLP as “a potentially malignant disorder,” it is still a matter of debate which mechanisms drive OLP to such a condition. The current hypothesis connecting OLP and OSCC is that chronic inflammation results in crucial DNA damage which over time results in cancer development. Initial studies investigating the OLP and OSCC link were mainly retrospective clinical studies. Over the past years, several amount of information has accumulated, mainly from molecular studies on the OLP malignant potential. This article is a critical review of whether OLP has a malignant potential and, therefore, represents a model of preneoplastic inflammation.

Malignant or borderline mucinous cystic neoplasms have a larger number of loculi than mucinous cystadenoma: A retrospective study with MR

2007 ◽  
Vol 26 (1) ◽  
pp. 94-99 ◽  
Author(s):  
Yoshikazu Okamoto ◽  
Yumiko O. Tanaka ◽  
Hajime Tsunoda ◽  
Hiroyuki Yoshikawa ◽  
Manabu Minami
Keyword(s):  
Retrospective Study ◽  
Mucinous Cystadenoma ◽  
Cystic Neoplasms ◽  
Mucinous Cystic Neoplasms
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