scholarly journals Sugammadex for Reversal of Neuromuscular Blockade in a Patient With Renal Failure

2019 ◽  
Vol 24 (3) ◽  
pp. 238-241
Author(s):  
Kayla Pfaff ◽  
Dmitry Tumin ◽  
Joseph D. Tobias
Keyword(s):  
Renal Failure ◽  
Neuromuscular Blockade ◽  
Neuromuscular Blocking ◽  
Water Soluble ◽  
Renal Elimination ◽  
Respiratory Complications ◽  
Soluble Complex ◽  
Residual Neuromuscular Blockade ◽  
Postoperative Respiratory Complications ◽  
Water Soluble Complex

Residual neuromuscular blockade following the use of non-depolarizing neuromuscular blocking agents (NMBAs) can lead to postoperative respiratory complications, including oxygen desaturation, atelectasis, and pneumonia. Sugammadex rapidly reverses steroidal NMBAs by encapsulating them in a highly stable water-soluble complex. This NMBA-sugammadex complex then undergoes renal elimination. In patients with renal insufficiency or failure, concern has been expressed regarding the elimination of the NMBA-sugammadex complex. We present a 19-year-old patient with renal failure who received sugammadex for reversal of neuromuscular blockade. The use of sugammadex in patients with renal dysfunction is discussed and safety concerns are reviewed.

A STUDY OF A WATER-SOLUBLE COMPLEX OF PRODIGIOSIN PRODUCED BY A STRAIN OF SERRATIA MARCESCENS

1962 ◽  
Vol 40 (1) ◽  
pp. 1019-1024 ◽  
Author(s):  
Seiichi Yoshida
Keyword(s):  
Molecular Weight ◽  
Light Scattering ◽  
Serratia Marcescens ◽  
Average Molecular Weight ◽  
Electrophoretic Analysis ◽  
Water Soluble ◽  
Soluble Complex ◽  
Ph Values ◽  
Scattering Measurements ◽  
Water Soluble Complex

A water-soluble pigment excreted from Serratia marcescens has been purified by precipitation with ammonium sulphate, dialysis, and ultracentrifugation at different pH values. The purified pigment showed a single band in the ultracentrifuge and by electrophoretic analysis at several pH values. An average molecular weight of 5 × 106 was calculated from light-scattering measurements. This pigment is composed of carbohydrate and protein combined with prodigiosin, and several properties of the complex are described.

A STUDY OF A WATER-SOLUBLE COMPLEX OF PRODIGIOSIN PRODUCED BY A STRAIN OF SERRATIA MARCESCENS

1962 ◽  
Vol 40 (8) ◽  
pp. 1019-1024 ◽  
Author(s):  
Seiichi Yoshida
Keyword(s):  
Molecular Weight ◽  
Light Scattering ◽  
Serratia Marcescens ◽  
Average Molecular Weight ◽  
Electrophoretic Analysis ◽  
Water Soluble ◽  
Soluble Complex ◽  
Ph Values ◽  
Scattering Measurements ◽  
Water Soluble Complex

A water-soluble pigment excreted from Serratia marcescens has been purified by precipitation with ammonium sulphate, dialysis, and ultracentrifugation at different pH values. The purified pigment showed a single band in the ultracentrifuge and by electrophoretic analysis at several pH values. An average molecular weight of 5 × 106 was calculated from light-scattering measurements. This pigment is composed of carbohydrate and protein combined with prodigiosin, and several properties of the complex are described.

Rietveld refinement of YbCoO3 prepared from aqueous solution-gel precursor

2007 ◽  
Vol 22 (1) ◽  
pp. 35-39 ◽  
Author(s):  
L. Ben Farhat ◽  
R. Ben Hassen ◽  
L. Dammak
Keyword(s):  
Cell Parameter ◽  
Rietveld Method ◽  
Polycrystalline Sample ◽  
Water Soluble ◽  
Complex Method ◽  
X Ray Diffraction ◽  
Soluble Complex ◽  
X Ray ◽  
The Relationship ◽  
Water Soluble Complex

A polycrystalline sample of YbCoO3 was prepared using a water-soluble complex method at relatively low temperatures. Common chelating ligands such as citric acid were employed for the synthesis of complex-based precursors, followed by thermal decomposition of the precursors at high temperatures. X-ray diffraction data were collected and the crystal structure was refined by the Rietveld method. The structure of YbCoO3 can be described as a sesquioxide C-M2O3-like structure with space group Ia-3 and unit-cell parameter a=10.4470 (2). The Yb3+ and the Co3+ cations are found to preferentially occupy the two nonequivalent 8d and 24d sites, respectively. The two independent atoms Yb/Co have octahedral coordination; however, the degrees of distortion of their coordination polyhedron are different. The relationship between the title compound and the orthorhombic Perovskite structure of YbCoO3 reported in the literature is established.

Ruthenium(II) Complexes of Thiosemicarbazones: The First Water-Soluble Complex with pH-Dependent Antiproliferative Activity

2007 ◽  
Vol 2007 (18) ◽  
pp. 2870-2878 ◽  
Author(s):  
Sanja Grguric-Sipka ◽  
Christian R. Kowol ◽  
Seied-Mojtaba Valiahdi ◽  
Rene Eichinger ◽  
Michael A. Jakupec ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Water Soluble ◽  
Soluble Complex ◽  
Ph Dependent ◽  
Water Soluble Complex
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