Cytopathologic follow-up of women with cervical cancer post-radiotherapy: case series

The distribution of human papillomavirus (HPV) types in cervical cancers is essential for design and evaluation of HPV type-specific vaccines. To follow up on a previous report that HPV types 35 and 58 were the dominant HPV types in cervical neoplasia in Mozambique, the HPV types in a consecutive case series of 74 invasive cervical cancers in Mozambique were determined. The most common worldwide major oncogenic HPV types 16 and 18 were present in 69 % of cervical cancers, suggesting that a vaccine targeting HPV-16 and -18 would have a substantial impact on cervical cancer also in Mozambique.

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The role of routine follow-up after gynecological malignancy

International Journal of Gynecological Cancer ◽

10.1136/ijgc-00009577-200505000-00001 ◽

2005 ◽

Vol 15 (3) ◽

pp. 413-419 ◽

Cited By ~ 9

Author(s):

F. M. Kew ◽

A. P. Roberts ◽

D. J. Cruickshank

Keyword(s):

Cervical Cancer ◽

Endometrial Cancer ◽

Poster Presentation ◽

Survival Benefit ◽

Gynecological Cancer ◽

Case Series ◽

Gynecological Malignancy ◽

Vulval Cancer ◽

Prospective Research

The objective of this article was to determine the evidence base for routine follow-up after gynecological malignancy. Only articles with a survival analysis were included. Relevant articles were identified by a comprehensive literature search of the main biomedical databases, hand searching of references of selected articles, and expert spotting of relevant journals and proceedings of international meetings. A two-stage extraction of data was undertaken. No prospective trials were identified. Twenty-nine retrospective case series analyses and one poster presentation met the inclusion criteria. Eight articles and one letter on endometrial cancer, six articles and one poster presentation on cervical cancer, and two articles in vulval cancer were reviewed. Only one article in endometrial cancer showed any survival benefit from routine follow-up, but it was of very poor methodologic quality. Two articles found a survival benefit from routine follow-up after cervical cancer. The two articles on vulval cancer did not find any survival benefit from routine review. There is no prospective research on the benefits of routine follow-up after gynecological cancer. Retrospective evidence calls in to question the benefit of universal follow-up. Prospective research is urgently needed.

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Emergency Embolization of Pelvic Vessels in Patients With Locally Advanced Cervical Cancer and Massive Vaginal Bleeding: A Case Series in a Latin American Oncological Center

JCO Global Oncology ◽

10.1200/go.20.00239 ◽

2020 ◽

pp. 1376-1383

Author(s):

Adriana Alméciga ◽

Juliana Rodriguez ◽

Julián Beltrán ◽

James Sáenz ◽

Abel Merchán ◽

...

Keyword(s):

Cervical Cancer ◽

Latin American ◽

Vaginal Bleeding ◽

Recurrent Disease ◽

Locally Advanced ◽

Case Series ◽

Severe Bleeding ◽

Advanced Cervical Cancer ◽

Locally Advanced Cervical Cancer

PURPOSE Locally advanced cervical cancer may present with uncontrollable vaginal bleeding in up to 70% of cases. Pelvic vessel embolization has been used as an urgent maneuver for achieving fast hemostatic control. This report describes outcomes of selective pelvic vessel embolization in patients with severe bleeding due to a locally advanced cervical cancer. METHODS In this retrospective study, technical aspects, clinical variables, and bleeding-related morbidity were described. The frequency of recurrent disease and the vital status at 1 year of follow-up were determined. Analysis was performed with statistical software R, version 3.6.2. The setting was Instituto Nacional de Cancerología- Bogotá, Colombia, between January 2009 and July 2017. RESULTS A total of 47 patients were included. Median age was 44 years (range, 26-70 years). The pre-embolization median hemoglobin level was 7.9 g/dL (range, 5.0-11.3 g/dL). Blood transfusions were administered to 41 women (87.2%). Bleeding control was achieved in 95.7% of cases in the first 24 hours after the embolization. There were no major complications. In 17 cases (36.2%), minor complications were reported; the most common was pelvic pain. In 17.1% of cases, a second embolization was required. After 12 months of follow-up, 27.7% of patients were alive without disease, 44.7% were alive with disease, and 25.5% of them have died of cervical cancer progression. CONCLUSION Selective pelvic vessel embolization is a useful alternative in patients with locally advanced cervical cancer and life-threatening bleeding. Its impact on recurrent disease and death due to oncologic cause is not clear.

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224 Metastatic cervical cancer treated with paclitaxel, ifosfamide and cisplatin (TIP), followed by local treatment and long-term follow up: case series

10.1136/ijgc-2019-igcs.224 ◽

2019 ◽

Author(s):

G Zibetti Dal Molin ◽

M Martello Gonçalves ◽

L Gomes ◽

CL Borrelli ◽

RMA Pereira ◽

...

Keyword(s):

Cervical Cancer ◽

Local Treatment ◽

Case Series ◽

Long Term Follow Up

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Low-income minority women at risk for cervical cancer: a process to improve adherence to follow-up recommendations

Public Health Reports ◽

10.1016/s0033-3549(04)50094-8 ◽

2001 ◽

Vol 116 (6) ◽

pp. 608-616 ◽

Cited By ~ 20

Author(s):

Virginia A Cardin ◽

Richard M Grimes ◽

Zhi Dong Jiang ◽

Nancy Pomeroy ◽

Luther Harrell ◽

...

Keyword(s):

Cervical Cancer ◽

At Risk ◽

Low Income ◽

Minority Women

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Three-year follow-up of women who participated in a prison cervical cancer screening intervention

PsycEXTRA Dataset ◽

10.1037/e508992013-086 ◽

2005 ◽

Author(s):

Ruth Elwood Martin ◽

Greg Hislop ◽

Veronika Moravan ◽

Garry Grams ◽

Betty Calam

Keyword(s):

Cervical Cancer ◽

Cancer Screening ◽

Cervical Cancer Screening

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Effect of Isolated Medial Patellofemoral Ligament Reconstruction in Patellofemoral Instability Regardless of Predisposing Factors

The Journal of Knee Surgery ◽

10.1055/s-0040-1713898 ◽

2020 ◽

Author(s):

Jae Ik Lee ◽

Mohd Shahrul Azuan Jaffar ◽

Han Gyeol Choi ◽

Tae Woo Kim ◽

Yong Seuk Lee

Keyword(s):

Medial Patellofemoral Ligament ◽

Trochlear Dysplasia ◽

Case Series ◽

Patellofemoral Instability ◽

International Knee Documentation Committee ◽

Predisposing Factors ◽

Mpfl Reconstruction ◽

Patellar Tilt ◽

Case Series Study

AbstractThe purpose of this study was to evaluate the outcomes of isolated medial patellofemoral ligament (MPFL) reconstruction, regardless of the presence of predisposing factors. A total of 21 knees that underwent isolated MPFL reconstruction from March 2014 to August 2017 were included in this retrospective series. Radiographs of the series of the knee at flexion angles of 20, 40, and 60 degrees were acquired. The patellar position was evaluated using the patellar tilt angle, sulcus angle, congruence angle (CA), and Caton-Deschamps and Blackburne-Peel ratios. To evaluate the clinical outcome, the preoperative and postoperative International Knee Documentation Committee (IKDC) and Lysholm knee scoring scales were analyzed. To evaluate the postoperative outcomes based on the predisposing factors, the results were separately analyzed for each group. Regarding radiologic outcomes, 20-degree CA was significantly reduced from 10.37 ± 5.96° preoperatively to −0.94 ± 4.11° postoperatively (p = 0.001). In addition, regardless of the predisposing factors, delta values of pre- and postoperation of 20-degree CA were not significantly different in both groups. The IKDC score improved from 53.71 (range: 18–74) preoperatively to 94.71 (range: 86–100) at the last follow-up (p = 0.004), and the Lysholm score improved from 54.28 (range: 10–81) preoperatively to 94.14 (range: 86–100) at the last follow-up (p = 0.010). Isolated MPFL reconstruction provides a safe and effective treatment for patellofemoral instability, even in the presence of mild predisposing factors, such as trochlear dysplasia, increased patella height, increased TT–TG distance, or valgus alignment. This is a Level 4, case series study.

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