Diabetes mellitus is metabolic syndrome characterized by disorder in
metabolism of carbon hydrates, lipids and proteins. The diagnosis of diabetes
is established by measuring the blood glucose level using standardized
methods. Frequent monitoring of blood glucose level could be inconvenient for
patients because of possible pain during blood sample taking. In the last few
years biological materials with non invasive sampling, like saliva, have been
analyzed. Research has confirmed that some organic and inorganic components
of saliva are modified in diabetic patients (glucose, lipid and protein
components, oxidative stress markers, electrolytes). Beside other markers,
the analysis of glucose in saliva is an attempt to find a non-invasive and
painless way for frequent monitoring of glucose concentration in diabetic
patients. Collecting saliva is simple and economical, it neither requires
expensive equipment nor specially trained staff. Saliva can be taken many
times and in unlimited quantity. In regards to the data about the
possibilities for using saliva as biological sample in monitoring diabetes
mellitus, which could be alternative to blood serum or plasma, the conclusion
is that saliva becomes more important in this context.
Ultraviolet to visible spectrophotometry observation to find appropriate wavelength for non-invasive blood glucose level measurement optical device
