Synthesis, Characterization and Antimicrobial Activities of Mixed Ligand Complexes of Transition Metals using 2-Aminophenol and 2-Chloroaniline as Ligands

A series of four mixed ligand complexes synthesized by reacting benzoylacetone and salicylaldehyde with different metal chlorides in ethanolic medium, were tested for their antimicrobial studies and indicated that the compounds are active against microorganisms used (Escherichia coli, Staphylococcus aureus, and Candida albicans) when compared with the activity of the reference or standard drugs (Erythromycin and Suptrin).Keywords: Antimicrobial, Synthesis, Ligands, Complexes

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Synthesis, Characterization and Antimicrobial Activities of Some Mixed-Ligand Complexes

Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry ◽

10.1080/00945710009351856 ◽

2000 ◽

Vol 30 (8) ◽

pp. 1617-1627 ◽

Cited By ~ 4

Author(s):

K. N. Patel ◽

K. M. Patel ◽

N. H. Patel ◽

C. R. Patel ◽

M. N. Patel

Keyword(s):

Antimicrobial Activities ◽

Mixed Ligand ◽

Mixed Ligand Complexes

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Synthesis of mixed ligand complexes of pyruvic acid thiosemicarbazone and acetone semicarbazone with transition metals

International Journal of Current Research in Chemistry and Pharmaceutical Sciences ◽

10.22192/ijcrcps.2017.04.01.002 ◽

2017 ◽

Vol 4 (2) ◽

pp. 5-9 ◽

Cited By ~ 1

Author(s):

P.R. Shirode ◽

◽

P.M. Yeole ◽

Keyword(s):

Transition Metals ◽

Pyruvic Acid ◽

Mixed Ligand ◽

Mixed Ligand Complexes

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Synthesis, characterisation and antimicrobial activities of mixed ligand complexes of Mn (II), Fe (II) and Co(II) containing N,N'-bis (o-anisaldehyde) p-phenylenediamine (tetradentate schiff base) and gylcine

Bayero Journal of Pure and Applied Sciences ◽

10.4314/bajopas.v11i1.6 ◽

2018 ◽

Vol 11 (1) ◽

pp. 32-36

Author(s):

I.T. Siraj ◽

M Sule

Keyword(s):

Antimicrobial Activity ◽

Schiff Base ◽

Mixed Ligand Complex ◽

Antimicrobial Activities ◽

Molar Conductance ◽

Bidentate Ligand ◽

Mixed Ligand ◽

Mixed Ligand Complexes ◽

Ligand Complex ◽

Tetradentate Schiff Base

Complexes of Mn(II), Fe(II) and Co(II) containing N, N’-bis[o-anisaldehyde]p-phenylenediamine tetradentate Schiff base as primary ligand and glycine as secondary bidentate ligand have been synthesized by reflux in 1:1:1 mole ratio and characterized both analytically and spectroscopically. Molar conductance measurement (69.02 to 86.30Ω–1 cm2 mol–1) of the complexes indicated they are weak electrolyte and magnetic susceptibility measurement shows values in range of 4.53 to 5.59BM indicating their paramagnetism. The infrared data suggested that the Schiff base coordinated via the two nitrogen atoms of the azomethine groups (1628 to 1680 cm-1) and the oxygen atoms of the adjacent methoxy groups (1341 to 1389 cm-1), while glycine coordinated via the nitrogen atom of the amino group (3060-3324 cm-1) and the oxygen atom of the carboxylate anion. Based on the analytical and spectroscopic data the complexes may be assigned an octahedral geometries and molecular formulae of the form [M(L)Gly], where M = Mn, Fe and Co, L=Schiff base and Gly = glycine. The Schiff base and its mixed ligand complexes were screened for antimicrobial activity against Staphylococcus aureus, Escherichia coli, Salmonella typhi, Mucor inducus and Aspergillus fumigatus. The complexes exhibited enhanced antimicrobial activity (10mm to 18mm) at 60 µg/disc as compared to 10mm activity of the uncoordinated Schiff base at the same concentration.Keywords: Mixed ligand complex; Schiff base, Glycine, p-phenylenediamine, o-anisaldehyde

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