scholarly journals Deviated nose: Physiological and pathological changes of the nasal cavity

2020 ◽  
Vol 47 (6) ◽  
pp. 505-515
Author(s):  
Taek Kyun Kim ◽  
Jae Yong Jeong

Deviated nose is highly challenging in rhinoplasty since the surgeon should consider both aesthetic and functional aspects of the nose. Deviated nose correction is surgically complex, and a thorough understanding of the mechanical and physiological changes of intranasal structures, including the septum and turbinates, is necessary for functional improvement.

2019 ◽  
Vol 13 (2) ◽  
pp. 62-69
Author(s):  
Riccardo Pofi ◽  
Jeremy W Tomlinson

The physiological changes that occur during pregnancy include altered regulation of the hypothalamo-pituitary-adrenal axis. The fetoplacental unit plays a major role in this, together with alteration of circulating cortisol-binding globulin levels, with a net effect to increase both total and free cortisol levels. Importantly, there are several pathological conditions that require steroid treatment or replacement during pregnancy, and optimizing therapy is clearly crucial. The potential for acute and chronic adverse effects that can impact upon both the mother and the fetus makes the decision of how and when to instigate steroid therapy particularly challenging. In this review, we describe the physio-pathological changes to the hypothalamo-pituitary-adrenal axis that occur during pregnancy, tools to assess endogenous glucocorticoid reserve as well as discuss treatment strategies and the potential for the development of adverse events.


2017 ◽  
Vol 82 (4) ◽  
pp. 39 ◽  
Author(s):  
A. I. Kryukov ◽  
G. Yu. Tsarapkin ◽  
A. S. Tovmasyan ◽  
S. G. Arzamazov ◽  
Z. O. Zaoeva ◽  
...  

2012 ◽  
Vol 11 (6) ◽  
pp. 529-541 ◽  
Author(s):  
Aditi Sahu ◽  
Atul Deshmukh ◽  
A. D. Ghanate ◽  
S. P. Singh ◽  
Pankaj Chaturvedi ◽  
...  

2021 ◽  
Vol 23 (3) ◽  
pp. 216-221
Author(s):  
Anna A. Zubareva ◽  
◽  
Sergey A. Karpishchenko ◽  
Marina A. Shavgulidze ◽  
◽  
...  

The choice of diagnostic tactics and methods of conservative and surgical treatment of mixed polypous and polypous-purulent types of chronic rhinosinusitis in patients with concomitant dentoalveolar pathology, comorbid somatic pathology depends on the availability of clinic’s technical supply and the patient's mood to make the optimal choice. The literature does not provide a unified algorithm for the examination and management of patients with chronic mixed polypous and polypous-purulent types of sinusitis occurring against the background of dentoalveolar pathology. Aim. Justification of differentiated approach to the diagnosis of chronic mixed polypous and polypous-purulent rhinosinusitis in patients with dentoalveolar pathology. Materials and methods. In 200 patients with these types of rhinosinusitis, pathological changes in the paranasal sinuses, nasal cavity and dentoalveolar apparatus were revealed. Results. In activation of the focus of odontogenic infection, pathological changes in the nasal cavity and paranasal sinuses were more severe at the side of odontogenic infection focus; in inactive odontogenic process and in presence of rhinogenic provoking factors, the severity of pathological changes in the nasal cavity and paranasal sinuses were similar at both sides. With each relapse of activation of the focus of odontogenic infection, the duration and severity of sinusitis increased. Conclusion. The basic diagnostic method for examining patients with mixed polypous and polypous-purulent types of chronic sinusitis in combination with dentoalveolar pathology is cone-beam computed tomography, which let to assess the severity of odontogenic infection focus against the background of pathological changes in the nasal cavity and paranasal sinuses to select the optimal therapeutic tactics.


Author(s):  
C. Uphoff ◽  
C. Nyquist-Battie

Fetal Alcohol Syndrone (FAS) is a syndrome with characteristic abnormalities resulting from prenatal exposure to ethanol. In many children with FAS syndrome gross pathological changes in the heart are seen with septal defects the most prevalent abnormality recorded. Few studies in animal models have been performed on the effects of ethanol on heart development. In our laboratory, it has been observed that prenatal ethanol exposure of Swiss albino mice results in abnormal cardiac muscle ultrastructure when mice were examined at birth and compared to pairfed and normal controls. Fig. 1 is an example of the changes that are seen in the ethanol-exposed animals. These changes include enlarged mitochondria with loss of inner mitochondrial membrane integrity and loss of myofibrils. Morphometric analysis substantiated the presence of these alterations from normal cardiac ultrastructure. The present work was undertaken to determine if the pathological changes seen in the newborn mice prenatally exposed to ethanol could be reversed with age and abstinence.


2020 ◽  
Vol 34 (3) ◽  
pp. 192-201
Author(s):  
Melanie M. van der Ploeg ◽  
Jos F. Brosschot ◽  
Markus Quirin ◽  
Richard D. Lane ◽  
Bart Verkuil

Abstract. Stress-related stimuli may be presented outside of awareness and may ultimately influence health by causing repetitive increases in physiological parameters, such as blood pressure (BP). In this study, we aimed to corroborate previous studies that demonstrated BP effects of subliminally presented stress-related stimuli. This would add evidence to the hypothesis that unconscious manifestations of stress can affect somatic health. Additionally, we suggest that these findings may be extended by measuring affective changes relating to these physiological changes, using measures for self-reported and implicit positive and negative affectivity. Using a repeated measures between-subject design, we presented either the prime word “angry” ( n = 26) or “relax” ( n = 28) subliminally (17 ms) for 100 trials to a student sample and measured systolic and diastolic BP, heart rate (HR), and affect. The “angry” prime, compared to the “relax” prime, did not affect any of the outcome variables. During the priming task, a higher level of implicit negative affect (INA) was associated with a lower systolic BP and diastolic BP. No association was found with HR. Self-reported affect and implicit positive affect were not related to the cardiovascular (CV) activity. In sum, anger and relax primes elicited similar CV activity patterns, but implicit measures of affect may provide a new method to examine the relationship between (unconscious) stress and health.


1978 ◽  
Vol 23 (9) ◽  
pp. 623-624
Author(s):  
MARIS MONITZ RODGON

2007 ◽  
Author(s):  
Michael K. McBeath ◽  
Flavio DaSilva ◽  
Thomas G. Sugar ◽  
Nancy E. Wechsler ◽  
James Koeneman

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