scholarly journals Higher Risk of Lymph Node Metastasis in Young Patients with Early Gastric Cancer

2019 ◽  
Vol 10 (18) ◽  
pp. 4389-4396 ◽  
Author(s):  
Zu-Kai Wang ◽  
Jian-Xian Lin ◽  
Ping Li ◽  
Jian-Wei Xie ◽  
Jia-Bin Wang ◽  
...  

2021 ◽  
Author(s):  
Weijun Wang ◽  
Suya Pang ◽  
Zeyu Wang ◽  
Xin Jiang ◽  
Rong Lin

Abstract Background: Recent studies have shown that young patients with gastric cancer (GC) are at a more advanced stage and have poor survival, but the cause is still unclear. And the prognosis of GC is closely related to Lymph node metastasis (LNM). It has been reported that age and LNM of superficial colorectal cancer are inversely proportional, but the relationship between age and prognosis in early gastric cancer (EGC) is currently unclear. Therefore, we aimed to study the relationship between age and the risk of LNM in EGC.Materials and Methods: We screened out patients with EGC who underwent surgery from the SEER research database from 1975 to 2016, and retrospectively analyzed the proportion of LNM in different age groups. The correlation between age and LNM was examined using univariate analysis and multivariate logistic regression analysis.Results: We included 9231 patients with EGC, and divided into 18-39 years old (2.3%), 40-49 (6.1%), 50-59 years old (15.7%), 60-69 years old (24.8%), 70-79 years old (27.2%) and ≥89 years old (23.9%) age group, and the proportions of lymph node metastasis were 20.3%, 23.3%, 21.0%, 19.8%, 18.1%, and 13.2 %. We found that as the age increases, the risk of LNM and postoperative survival time of EGC patients decrease (p<0.001). Conclusions: This study found that age in patients with EGC was inversely related to the risk of LNM, and positively correlated with postoperative survival. For older patients with EGC, endoscopic treatment is more appropriate. For young patients with EGC, LNM should be considered when choosing endoscopic treatment.



2011 ◽  
Vol 15 (2) ◽  
pp. 221-225 ◽  
Author(s):  
Hisaharu Oya ◽  
Takuji Gotoda ◽  
Tetsu Kinjo ◽  
Haruhisa Suzuki ◽  
Shigetaka Yoshinaga ◽  
...  


2007 ◽  
Vol 19 (2) ◽  
pp. 89-93
Author(s):  
Cai-Gang Liu ◽  
Ping Lu ◽  
Yang Lu ◽  
Rui-shan Zhang ◽  
Feng Jin ◽  
...  


1998 ◽  
Vol 114 ◽  
pp. A623
Author(s):  
HR Kim ◽  
SJ Pang ◽  
HY Jung ◽  
WS Hong ◽  
YI Min ◽  
...  


2019 ◽  
Vol 29 (9) ◽  
pp. 1105-1110 ◽  
Author(s):  
Ji Won Kim ◽  
Hyuk Lee ◽  
Yang Won Min ◽  
Byung-Hoon Min ◽  
Jun Haeng Lee ◽  
...  


2011 ◽  
Vol 2 (6) ◽  
pp. 1197-1202 ◽  
Author(s):  
IK-CHAN SONG ◽  
ZHE-LONG LIANG ◽  
JUNG-CHAN LEE ◽  
SONG-MEI HUANG ◽  
HA-YON KIM ◽  
...  




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