Yellow fever vaccine in Brazil: fighting a tropical scourge, modernising the nation

Author(s):  
Jaime Benchimol

This chapter shows how successive yellow fever vaccines, conceived as complex sociotechnical constructs, have been involved in the construction of the Brazilian nation state. Three distinct periods in the country’s political history are distinguished: the patriarchal oligarchic state (1822-1930), the national developmentalist state (1930-80), and the state which has since then oscillated between liberal dependency and national interventionism. The successful campaigns against yellow fever run by Oswaldo Cruz formed the backbone for the founding myth of scientific public health and medicine in Brazil. The trajectory of the yellow fever vaccine manufactured at the Oswaldo Cruz Institute, which eventually became the biggest producer worldwide, coincides with economic, welfare, and labour policies that principally benefited urban groups. Rural populations would be the main recipients of the yellow fever vaccine, and it became an important component when national agencies tackled endemic diseases in the interior. Immunisation programmes have helped strengthen the country’s health system, disseminating a culture of prevention. The social mobilisation achieved by the yellow fever and other vaccination campaigns led to new relationships between communities and health services.

2021 ◽  
pp. 1-17
Author(s):  
N.I. Fisher ◽  
D.J. Trewin

Given the high level of global mobility, pandemics are likely to be more frequent, and with potentially devastating consequences for our way of life. With COVID-19, Australia is in relatively better shape than most other countries and is generally regarded as having managed the pandemic well. That said, we believe there is a critical need to start the process of learning from this pandemic to improve the quantitative information and related advice provided to policy makers. A dispassionate assessment of Australia’s health and economic response to the COVID-19 pandemic reveals some important inadequacies in the data, statistical analysis and interpretation used to guide Australia’s preparations and actions. For example, one key shortcoming has been the lack of data to obtain an early understanding of the extent of asymptomatic and mildly symptomatic cases or the differences across age groups, occupations or ethnic groups. Minimising the combined health, social and economic impacts of a novel virus depends critically on ongoing acquisition, integration, analysis, interpretation and presentation of a variety of data streams to inform the development, execution and monitoring of appropriate strategies. The article captures the essential quantitative components of such an approach for each of the four basic phases, from initial detection to post-pandemic. It also outlines the critical steps in each stage to enable policy makers to deal more efficiently and effectively with future such events, thus enhancing both the social and the economic welfare of its people. Although written in an Australian context, we believe most elements would apply to other countries as well.


Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 173
Author(s):  
Davide Gori ◽  
Chiara Reno ◽  
Daniel Remondini ◽  
Francesco Durazzi ◽  
Maria Pia Fantini

While the SARS-CoV-2 pandemic continues to strike and collect its death toll throughout the globe, as of 31 January 2021, the vaccine candidates worldwide were 292, of which 70 were in clinical testing. Several vaccines have been approved worldwide, and in particular, three have been so far authorized for use in the EU. Vaccination can be, in fact, an efficient way to mitigate the devastating effect of the pandemic and offer protection to some vulnerable strata of the population (i.e., the elderly) and reduce the social and economic burden of the current crisis. Regardless, a question is still open: after vaccination availability for the public, will vaccination campaigns be effective in reaching all the strata and a sufficient number of people in order to guarantee herd immunity? In other words: after we have it, will we be able to use it? Following the trends in vaccine hesitancy in recent years, there is a growing distrust of COVID-19 vaccinations. In addition, the online context and competition between pro- and anti-vaxxers show a trend in which anti-vaccination movements tend to capture the attention of those who are hesitant. Describing this context and analyzing its possible causes, what interventions or strategies could be effective to reduce COVID-19 vaccine hesitancy? Will social media trend analysis be helpful in trying to solve this complex issue? Are there perspectives for an efficient implementation of COVID-19 vaccination coverage as well as for all the other vaccinations?


Author(s):  
Roberto Vignapiano ◽  
Lidia Vicchio ◽  
Eleonora Favuzza ◽  
Michela Cennamo ◽  
Rita Mencucci

2021 ◽  
pp. 135245852110063
Author(s):  
Caroline Papeix ◽  
Julie Mazoyer ◽  
Elisabeth Maillart ◽  
Caroline Bensa ◽  
Anne-Laure Dubessy ◽  
...  

Background: Yellow fever vaccine (YFV) is not advised for multiple sclerosis (MS) patients because of the potential risk of post-vaccine relapses. Objective: To assess the risk of relapsing-remitting multiple sclerosis (RR-MS) worsening after YFV. Methods: Non-interventional observational retrospective, exposed/non-exposed cohort study nested in the French national cohort including MS. Results: 128 RR-MS were included. The 1-year annualized relapse rate (ARR) following YFV did not differ between exposed: 0.219 (0.420) and non-exposed subjects: 0.208 (0.521) ( p = 0.92). Time to first relapse was not different between groups (adjusted hazard ratio (HR) = 1.33; 95% confidence interval (CI) = 0.53–3.30, p = 0.54). Conclusion: These results suggest that YFV does not worsen the course of RR-MS.


2020 ◽  
Vol 101 ◽  
pp. 450
Author(s):  
D.E. Iglesias ◽  
C. Ezcurra ◽  
N. Garcia Allende ◽  
A.V. Sanchez ◽  
A. Risso Patrón ◽  
...  

Author(s):  
Laura Ramos de Almeida ◽  
Roberta Fachini Criado ◽  
Paulo Ricardo Criado ◽  
Luis Felipe Ensina ◽  
Beatrice Martinez Zugaib Abdalla ◽  
...  

2016 ◽  
Vol 45 ◽  
pp. 204 ◽  
Author(s):  
P. Doke ◽  
B. Purandare ◽  
D. Bhosle ◽  
P. Dave ◽  
S. Jagtap ◽  
...  

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