scholarly journals Herpes zoster following mRNA-1273 COVID-19 vaccination

2021 ◽  
Vol 12 (4) ◽  
pp. 464-465
Author(s):  
Alex Drohan ◽  
Glenn Kolansky ◽  
Zachary Kolansky
Keyword(s):  
Herpes Zoster ◽  
Skin Diseases ◽  
Similar Distribution ◽  
Post Herpetic Neuralgia ◽  
Vaccination Site ◽  
Vaccine Injection ◽  
Dermatology Clinic ◽  
Injection Site Reactions ◽  
The Right ◽  
Similar Distribution Pattern

Sir, Skin rashes have been associated with COVID-19 and studies suggest the inclusion of skin diseases in the list of COVID-19 symptoms. Skin eruptions are also associated with the mRNA-1273 COVID-19 vaccine. Findings by Baden et al. [1] describe immediate injection-site reactions observed in 84.2% of participants after the first dose, with delayed onset reactions—on or after day eight—occurring much more infrequently, 0.8% after the first dose and 0.2% after the second dose. Blumenthal et al. [2] discuss twelve cases of delayed vaccine reactions, with all patients experiencing reactions in the vaccination site. Herein, we describe two cases of herpes zoster within days of receiving their first mRNA-1273 vaccine. Both cases presented to the same dermatology clinic. A 77-year-old male presented with a bumpy, itchy, red rash on the upper right arm and axilla three days following an mRNA-1273 vaccine injection. The symptoms continued to worsen and the patient was clinically diagnosed with herpes zoster and treated with valacyclovir (Fig. 1). Another patient, also a 77-year-old male, complained of a rash located on the right upper arm and axilla. It was a red, itchy, bumpy rash that the patient developed two days after an mRNA-1273 vaccine injection (Fig. 2). Both rashes demonstrated a similar distribution pattern and both patients responded well to valacyclovir with the resolution of the erythema; however, one patient did have residual post-herpetic neuralgia.

Satistical Observations on Herpes Zoster Patients of the Dermatology Clinic, Nagoya National Hospital. Post-herpetic Neuralgia.

1991 ◽  
Vol 53 (5) ◽  
pp. 1012-1022 ◽  
Author(s):  
Mayumi IIDA ◽  
Tsuyoshi FURUTA ◽  
Mototsugu FUKAYA ◽  
Junichi HASEGAWA ◽  
Etsuko IWASE ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Post Herpetic Neuralgia ◽  
National Hospital ◽  
Dermatology Clinic

scholarly journals PROFIL HERPES ZOSTER DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R. D. KANDOU MANADO 2011-2013

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Dwi H. Danardono ◽  
Nurdjannah J. Niode
Keyword(s):  
Herpes Zoster ◽  
General Hospital ◽  
Medical Records ◽  
Antiviral Agent ◽  
Age Group ◽  
Post Herpetic Neuralgia ◽  
Thoracic Region ◽  
Varicella Zoster ◽  
Dermatology Clinic ◽  
Acute Viral Infection

Abstract: Herpes zoster is a reactivation of varicella zoster virus (VZV) that affects the skin and mucosa. The incidence of herpes zoster increases with age. There are three main goals of treatment: overcoming the acute viral infection, relief from acute pain, and prevention of post-herpetic neuralgia. This study aimed to determine the profile of herpes zoster in the Dermatology Clinic of Prof. Dr. R. D. Kandou General Hospital for three years based on the number of new cases, gender, ages, dermatome locations, and treatment. This was a retrospective study using the medical records of the Dermatology Clinic of Prof. Dr. R. D. Kandou General Hospital during period January 2011- Desember 2013. The results showed that there were 96 (0.84%) herpes zoster patients of 11,367 new patients, consisted of 51 (53.11%) males and 45 (46.87%) females. The most frequent age group was 45-64 years with a number of 59 cases (61.46%). The most frequent dermatome location was on the left thoracic region with a number of 18 cases (18.75%). The most widely prescribed treatment was a combination of antiviral agent, analgesic drugs, roborantia, and topical medicine (powder/antibiotic cream), with a number of 43 cases (44.79%).Keywords: herpes zoster, morbidityAbstrak: Herpes zoster merupakan reaktivasi virus varicella zoster (VZV) yang menyerang kulit dan mukosa. Insiden herpes zoster meningkat seiring dengan bertambahnya usia. Terdapat tiga tujuan utama pengobatan yaitu: mengatasi infeksi virus akut, mengatasi nyeri akut, dan mencegah timbulnya neuralgia pasca-herpetik. Penelitian ini bertujuan untuk mengetahui profil herpes zoster di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado yang meliputi jumlah kasus baru, jenis kelamin, usia, lokasi dermatom, dan terapi. Metode penelitian ialah retrospektif dengan menggunakan catatan medis pasien baru herpes zoster yang berobat di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado selama periode Januari 2011 hingga Desember 2013. Hasil penelitian memperlihatkan terdapat 96 (0,84%) kasus herpes zoster dari 11.367 pasien baru yang terdiri dari 51 (53,11%) laki-laki dan 45 (46,87%) perempuan. Kelompok usia terbanyak ialah 45-64 tahun sejumlah 59 kasus (61,46%). Lokasi dermatom tersering pada regio torakalis sinistra sejumlah 18 kasus (18,75%). Terapi yang paling sering diberikan ialah kombinasi antivirus, analgetik, roboransia, dan pengobatan topikal (bedak/cream antibiotika) sejumlah 43 kasus (44,79%).Kata kunci: herpes zoster, morbiditas

scholarly journals Ocular manifestations in Herpes Zoster Ophthalmicus

1970 ◽  
Vol 3 (2) ◽  
pp. 165-171 ◽  
Author(s):  
LR Puri ◽  
GB Shrestha ◽  
DN Shah ◽  
M Chaudhary ◽  
A Thakar
Keyword(s):  
Herpes Zoster ◽  
Young Patients ◽  
Ocular Involvement ◽  
Post Herpetic Neuralgia ◽  
Visual Disability ◽  
Herpes Zoster Ophthalmicus ◽  
Cross Sectional ◽  
Ocular Manifestations ◽  
Visual Status ◽  
The Mean

Background: Ocular complications of herpes zoster ophthalmicus (HZO) may lead to substantial visual disability, severe post-herpetic neuralgia and rarely fatal cerebral complications. Aim: To identify the pattern of ocular manifestation in herpes zoster ophthalmicus. Materials and methods: A cross-sectional descriptive study was under taken including the clinically diagnosed cases of HZO. All of them underwent a complete ophthalmological evaluation. Results: Sixty-eight cases of HZO were examined, of which 37 (54.4 %) were male and 31 (45.6%) female. The mean age was 48.7 ± 18.5 years. Most of the patients (64.7 %) were above the age of 40 years. 77.94 % of the patients had some form of ocular involvement. Pain (77.9 %) was the commonest ocular complaint. In young patients less than 35 years, HIV was the most common risk factor (19.3 %).Visual status was good in the majority (73.5 %) of patients at presentation. Lid and adnexal findings (45.8 %) were most common ocular involvement followed by conjunctivitis (41.1 %). Corneal complication was seen in 38.2 % of cases, uveitis in 19.1 % and post-herpetic neuralgia (PHN) and secondary glaucoma each in 5.8 %. Conclusion: Eyelid and ocular adnexal involvement is most commonly found in patients with herpes zoster ophthalmicus followed by corneal complication and uveitis. There needs to be awareness of ocular involvement, which can be sight threatening, among the HZO patients and other medical departments and an increased emphasis on regular ophthalmic examination. Key words: herpes virus, herpes zoster, conjunctivitis, keratitis DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5271 Nepal J Ophthalmol 2011; 3(2): 165-171

scholarly journals Lower back pain with sciatic disorder following L5 dermatome caused by herpes zoster infection

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Roslind Karolina Hackenberg ◽  
Arnd Von den Driesch ◽  
Dietmar Pierre König
Keyword(s):  
Back Pain ◽  
Herpes Zoster ◽  
Lower Back Pain ◽  
Pain Treatment ◽  
Acute Onset ◽  
Mri Scan ◽  
Lower Back ◽  
Acyclovir Treatment ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

We report the case of a 62-year-old patient with lower back pain radiating into the right leg accompanied by numbness. The pain had an acute onset and was resistant to conservative pain treatment. A magnetic resonance imaging (MRI) scan of the lumbar spine showed no degenerative discovertebral lesions, but a swelling of the nerve root supplying the affected dermatome. For pain treatment the patient received lumbar epidural infiltrations. During this treatment the patient suddenly developed a skin rash with grouped vesicular blisters on an erythematous ground. After the diagnosis of a lumbar herpes zoster and an acyclovir treatment, the patient could be discharged in an ameliorated condition. This case demonstrates the importance to consider rare causes of lumbosciatic pain and disorders and to acknowledge unspecific changes in a MRI scan.

Acupuncture in the Management of Herpes Zoster

1996 ◽  
Vol 14 (2) ◽  
pp. 80-83 ◽  
Author(s):  
Janet Boaler
Keyword(s):  
Herpes Zoster ◽  
Substantial Reduction ◽  
Ageing Population ◽  
Post Herpetic Neuralgia ◽  
Controlled Clinical Trials ◽  
Care Level ◽  
Primary Health ◽  
Acute Herpes Zoster ◽  
Pain Clinics ◽  
Distressing Condition

Although it has been demonstrated conclusively that anti-viral medication reduces the duration and intensity of the manifestations of acute herpes zoster, controversy remains concerning its effectiveness in preventing post herpetic neuralgia and patients with this distressing condition are often referred to Pain Clinics. The problem is likely to become more prevalent in the future due to the ageing population, particularly in those over 80 years of age. Research, most of it uncontrolled so far, suggests that simple acupuncture starting in the acute phase, within 24–72 hours of the appearance of the skin eruption, could, if combined with anti-viral medication, produce a substantial reduction in the incidence and severity of post herpetic neuralgia. Further controlled clinical trials conducted at primary health care level are urgently needed.

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