scholarly journals Using structural and functional brain imaging to uncover how the brain adapts to blindness

2015 ◽  
Vol 2 (1) ◽  
pp. 7
Author(s):  
Gabriella V Hirsch ◽  
Corinna M Bauer ◽  
Lotfi B Merabet
2020 ◽  
Vol 10 (8) ◽  
pp. 514
Author(s):  
Naho Konoike ◽  
Katsuki Nakamura

Our daily lives are filled with rhythmic movements, such as walking, sports, and dancing, but the mechanisms by which the brain controls rhythmic movements are poorly understood. In this review, we examine the literature on neuropsychological studies of patients with focal brain lesions, and functional brain imaging studies primarily using finger-tapping tasks. These studies suggest a close connection between sensory and motor processing of rhythm, with no apparent distinction between the two functions. Thus, we conducted two functional brain imaging studies to survey the rhythm representations relatively independent of sensory and motor functions. First, we determined brain activations related to rhythm processing in a sensory modality-independent manner. Second, we examined body part-independent brain activation related to rhythm reproduction. Based on previous literature, we discuss how brain areas contribute rhythmic motor control. Furthermore, we also discuss the mechanisms by which the brain controls rhythmic movements.


2009 ◽  
Author(s):  
E. J. Martin-Williams ◽  
A. Raabe ◽  
D. Van De Ville ◽  
M. Leutenegger ◽  
A. Szelényi ◽  
...  

PsycCRITIQUES ◽  
2017 ◽  
Vol 62 (50) ◽  
Author(s):  
Robert Perna ◽  
Jyoti Pundlik

Author(s):  
E.J. Martin-Williams ◽  
A. Raabe ◽  
D. Van De Ville ◽  
M. Leutenegger ◽  
A. Szelényi ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Mohammed Bermo ◽  
Mohammed Saqr ◽  
Hunter Hoffman ◽  
David Patterson ◽  
Sam Sharar ◽  
...  

Functional neuroimaging modalities vary in spatial and temporal resolution. One major limitation of most functional neuroimaging modalities is that only neural activation taking place inside the scanner can be imaged. This limitation makes functional neuroimaging in many clinical scenarios extremely difficult or impossible. The most commonly used radiopharmaceutical in Single Photon Emission Tomography (SPECT) functional brain imaging is Technetium 99 m-labeled Ethyl Cysteinate Dimer (ECD). ECD is a lipophilic compound with unique pharmacodynamics. It crosses the blood brain barrier and has high first pass extraction by the neurons proportional to regional brain perfusion at the time of injection. It reaches peak activity in the brain 1 min after injection and is then slowly cleared from the brain following a biexponential mode. This allows for a practical imaging window of 1 or 2 h after injection. In other words, it freezes a snapshot of brain perfusion at the time of injection that is kept and can be imaged later. This unique feature allows for designing functional brain imaging studies that do not require the patient to be inside the scanner at the time of brain activation. Functional brain imaging during severe burn wound care is an example that has been extensively studied using this technique. Not only does SPECT allow for imaging of brain activity under extreme pain conditions in clinical settings, but it also allows for imaging of brain activity modulation in response to analgesic maneuvers whether pharmacologic or non-traditional such as using virtual reality analgesia. Together with its utility in extreme situations, SPECTS is also helpful in investigating brain activation under typical pain conditions such as experimental controlled pain and chronic pain syndromes.


Sign in / Sign up

Export Citation Format

Share Document