scholarly journals A simple method for measuring long-term integrated testosterone levels in men

2016 ◽  
Author(s):  
Devorah Matas ◽  
Lee Koren
Keyword(s):  
Multiple Roles ◽  
Simple Method ◽  
Testosterone Levels ◽  
Age Trends ◽  
And Behavior ◽  
Potential Tool

Steroids play multiple roles in the regulation of development, physiology, reproduction, and behavior. Measuring circulating steroids is especially challenging since concentrations are extremely labile, responding to stressors within minutes. Matrices that integrate long-term steroid levels are therefore valuable as biomarkers of baseline, as well as chronic steroid exposures. Here we report on a simple method to extract and measure accumulated testosterone from human fingernails using commercial EIA kits. Further, we demonstrate known human testosterone sex and age trends. Thus, this method is a potential tool for biomonitoring endogenous as well as exogenous steroid exposure.

scholarly journals A simple method for measuring long-term integrated testosterone levels in men

2016 ◽  
Author(s):  
Devorah Matas ◽  
Lee Koren
Keyword(s):  
Multiple Roles ◽  
Simple Method ◽  
Testosterone Levels ◽  
Age Trends ◽  
And Behavior ◽  
Potential Tool

Steroids play multiple roles in the regulation of development, physiology, reproduction, and behavior. Measuring circulating steroids is especially challenging since concentrations are extremely labile, responding to stressors within minutes. Matrices that integrate long-term steroid levels are therefore valuable as biomarkers of baseline, as well as chronic steroid exposures. Here we report on a simple method to extract and measure accumulated testosterone from human fingernails using commercial EIA kits. Further, we demonstrate known human testosterone sex and age trends. Thus, this method is a potential tool for biomonitoring endogenous as well as exogenous steroid exposure.

scholarly journals A simple method for measuring long-term integrated testosterone levels in men

2016 ◽  
Author(s):  
Devorah Matas ◽  
Lee Koren
Keyword(s):  
Multiple Roles ◽  
Simple Method ◽  
Testosterone Levels ◽  
Age Trends ◽  
And Behavior ◽  
Potential Tool

Steroids play multiple roles in the regulation of development, physiology, reproduction, and behavior. Measuring circulating steroids is especially challenging since concentrations are extremely labile, responding to stressors within minutes. Matrices that integrate long-term steroid levels are therefore valuable as biomarkers of baseline, as well as chronic steroid exposures. Here we report on a simple method to extract and measure accumulated testosterone from human fingernails using commercial EIA kits. Further, we demonstrate known human testosterone sex and age trends. Thus, this method is a potential tool for biomonitoring endogenous as well as exogenous steroid exposure.

scholarly journals Age-related testosterone declines can be detected in men’s fingernails

2018 ◽  
Vol 96 (1) ◽  
pp. 76-79
Author(s):  
Devorah Matas ◽  
Lee Koren
Keyword(s):  
Enzyme Immunoassay ◽  
Multiple Roles ◽  
Social Situations ◽  
Simple Method ◽  
Age Related ◽  
Age Trends ◽  
Commercial Enzyme Immunoassay ◽  
And Behavior ◽  
Potential Tool

Testosterone plays multiple roles in the regulation of development, physiology, reproduction, and behavior. Age-related testosterone declines are expected in the population. However, measuring circulating testosterone is especially challenging because concentrations are labile, responding to social situations and challenges. Matrices that integrate long-term testosterone levels are therefore valuable as biomarkers of endogenous levels as well as chronic exposures. Here, we report on a simple method to extract and measure accumulated testosterone from human fingernails using commercial enzyme immunoassay kits. Furthermore, we demonstrate known human testosterone sex and age trends. Our method is especially useful for quantifying testosterone in men’s nails, where a small amount of matrix is required. Thus, this approach is a potential tool for biomonitoring endogenous as well as exogenous testosterone exposure. We suggest considering nails as an alternative matrix for quantifying other steroids as well.

Harvest rate of sooty shearwaters (Puffinus griseus) by Rakiura Māori: a potential tool to monitor population trends?

2004 ◽  
Vol 31 (3) ◽  
pp. 319 ◽  
Author(s):  
Jane Catherine Kitson
Keyword(s):  
New Zealand ◽  
Cross Section ◽  
Large Scale ◽  
Population Change ◽  
Population Trends ◽  
Harvest Rate ◽  
General Index ◽  
Careful Screening ◽  
Potential Tool

Sooty shearwaters (tītī, muttonbird, Puffinus griseus) are highly abundant migratory seabirds, which return to breeding colonies in New Zealand. The Rakiura Māori annual chick harvest on islands adjacent to Rakiura (Stewart Island), is one of the last large-scale customary uses of native wildlife in New Zealand. This study aimed to establish whether the rate at which muttonbirders can extract chicks from their breeding burrows indicates population trends of sooty shearwaters. Harvest rates increased slightly with increasing chick densities on Putauhinu Island. Birders' harvest rates vary in their sensitivities to changing chick density. Therefore a monitoring panel requires careful screening to ensure that harvest rates of the birders selected are sensitive to chick density, and represents a cross-section of different islands. Though harvest rates can provide only a general index of population change, it can provide an inexpensive and feasible way to measure population trends. Detecting trends is the first step to assessing the long-term sustainability of the harvest.

Think twice, it’s all right: Long lasting effects of disrupted reconsolidation on brain and behavior in human long-term fear

2017 ◽  
Vol 324 ◽  
pp. 125-129 ◽  
Author(s):  
Johannes Björkstrand ◽  
Thomas Agren ◽  
Fredrik Åhs ◽  
Andreas Frick ◽  
Elna-Marie Larsson ◽  
...  
Keyword(s):  
Brain And Behavior ◽  
And Behavior
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